Research Output 1971 2019

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2019
docetaxel
Estrogen Receptors
Single Nucleotide Polymorphism
Estrogens
Breast Neoplasms
1 Citation (Scopus)

Alpha-1 Antitrypsin Deficiency Liver Disease, Mutational Homogeneity Modulated by Epigenetic Heterogeneity With Links to Obesity

Wang, L., Marek, G. W., Hlady, R. A., Wagner, R. T., Zhao, X., Clark, V. C., Fan, A. X., Liu, C., Brantly, M. & Robertson, K. D., Jan 1 2019, In : Hepatology.

Research output: Contribution to journalArticle

alpha 1-Antitrypsin Deficiency
Deficiency Diseases
Epigenomics
5-Methylcytosine
Liver Diseases
2 Citations (Scopus)

Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons

Vadodaria, K. C., Ji, Y., Skime, M., Paquola, A. C., Nelson, T. J., Hall-Flavin, D., Heard, K. J., Fredlender, C., Deng, Y., Elkins, J., Dani, K., Le, A. T., Marchetto, M. C., Weinshilboum, R. M. & Gage, F. H., Jan 1 2019, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Major Depressive Disorder
Serotonin Uptake Inhibitors
Serotonergic Neurons
Neurons
Induced Pluripotent Stem Cells

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. M. & 1 others, Weinshilboum, R. M., Jan 1 2019, In : Clinical pharmacology and therapeutics.

Research output: Contribution to journalArticle

Open Access
Aromatase Inhibitors
Genome-Wide Association Study
Single Nucleotide Polymorphism
Pharmaceutical Preparations
Breast Neoplasms

A novel UCHL 3 inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homologous recombination-mediated DNA double strand break repair

Song, Z., Tu, X., Zhou, Q., Huang, J., Chen, Y., Liu, J., Lee, S. B., Kim, W., Nowsheen, S., Luo, K., Yuan, J. & Lou, Z., Jun 1 2019, In : Cell Death and Disease. 10, 6, 398.

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
Double-Stranded DNA Breaks
Homologous Recombination
DNA Damage
Ubiquitination

A pilot clinical trial testing topical resiquimod and a xenopeptide as immune adjuvants for a melanoma vaccine targeting MART-1

Block, M. S., Nevala, W. K., Pang, Y. P., Allred, J. B., Strand, C. & Markovic, S. N., Aug 1 2019, In : Melanoma research. 29, 4, p. 420-427 8 p.

Research output: Contribution to journalArticle

resiquimod
Melanoma
Vaccines
Clinical Trials
Appointments and Schedules

Bis(propyl)-cognitin potentiates rehabilitation of treadmill exercise after a transient focal cerebral ischemia, possibly via inhibiting NMDA receptor and regulating VEGF expression

Ke, Z., Hu, S., Cui, W., Sun, J., Zhang, S., Mak, S., Wang, J., Tang, J., Pang, Y-P., Han, Y. & Tong, K., Sep 1 2019, In : Neurochemistry International. 128, p. 143-153 11 p.

Research output: Contribution to journalArticle

Exercise Therapy
Transient Ischemic Attack
N-Methyl-D-Aspartate Receptors
Vascular Endothelial Growth Factor A
Pharmaceutical Preparations
1 Citation (Scopus)

Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice

Aziz, K., Limzerwala, J. F., Sturmlechner, I., Hurley, E., Zhang, C., Jeganathan, K. B., Nelson, G., Bronk, S., Fierro Velasco, R. O., van Deursen, E. J., O'Brien, D. R., Kocher, J-P., Youssef, S. A., van Ree, J. H., de Bruin, A., van den Bos, H., Spierings, D. C. J., Foijer, F., van de Sluis, B., Roberts, L. R. & 3 others, Gores, G. J., Li, H. & Van Deursen, J., Jul 1 2019, In : Gastroenterology. 157, 1, p. 210-226.e12

Research output: Contribution to journalArticle

Chromosomal Instability
Cyclins
Liver
Neoplasms
Chromosomes

Cell-level somatic mutation detection from single-cell RNA sequencing

Vu, T. N., Nguyen, H. N., Calza, S., Kalari, K. R., Wang, L. & Pawitan, Y., Nov 1 2019, In : Bioinformatics (Oxford, England). 35, 22, p. 4679-4687 9 p.

Research output: Contribution to journalArticle

Open Access
RNA Sequence Analysis
RNA
Sequencing
Mutation
Cell

Chronic caffeine exposure in adolescence promotes diurnal, biphasic mood-cycling and enhanced motivation for reward in adult mice

Hinton, D. J., Andres-Beck, L. G., Nett, K. E., Oliveros, A., Choi, S., Veldic, M. D. & Choi, D. S., Sep 16 2019, In : Behavioural Brain Research. 370, 111943.

Research output: Contribution to journalArticle

Caffeine
Reward
Motivation
Photoperiod
Locomotion
Lactic Acid
Brain
Homeostasis
Ethanol
Glucose
3 Citations (Scopus)

Clopidogrel Pharmacogenetics

Pereira, N. L., Rihal, C., So, D. Y. F., Rosenberg, Y., Lennon, R. J., Mathew, V., Goodman, S. G., Weinshilboum, R. M., Wang, L. M., Baudhuin, L. M., Lerman, A., Hasan, A., Iturriaga, E., Fu, Y. P., Geller, N., Bailey, K. R. & Farkouh, M. E., Apr 1 2019, In : Circulation. Cardiovascular interventions. 12, 4, p. e007811

Research output: Contribution to journalArticle

clopidogrel
Pharmacogenetics
Percutaneous Coronary Intervention
Alleles
Drug Labeling
1 Citation (Scopus)
Technetium Tc 99m Sestamibi
Molecular Imaging
Breast
Breast Neoplasms
Drug Therapy

DDX17 promotes hepatocellular carcinoma progression via inhibiting Klf4 transcriptional activity

Xue, Y., Jia, X., Li, C., Zhang, K., Li, L., Wu, J., Yuan, J. & Li, Q., Nov 1 2019, In : Cell Death and Disease. 10, 11, 814.

Research output: Contribution to journalArticle

Open Access
Hepatocellular Carcinoma
DEAD-box RNA Helicases
Gene Expression
Atlases
Zinc Fingers

Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer

Ingle, J. N., Kalari, K. R., Momozawa, Y., Kubo, M., Furukawa, Y., Shepherd, L. E., Ellis, M. J., Goss, P. E., Barman, P., Carlson, E. E., Sinnwell, J. P., Tang, X., Goetz, M. P., Chen, B. E., Cairns, J., Weinshilboum, R. M. & Wang, L. M., Oct 1 2019, In : Pharmacogenetics and genomics. 29, 8, p. 183-191 9 p.

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
Aromatase Inhibitors
Genome-Wide Association Study
Single Nucleotide Polymorphism
Breast Neoplasms

DNA methylation of individual repetitive elements in hepatitis C virus infection-induced hepatocellular carcinoma

Zheng, Y., Hlady, R. A., Joyce, B. T., Robertson, K. D., He, C., Nannini, D. R., Kibbe, W. A., Achenbach, C. J., Murphy, R. L., Roberts, L. R. & Hou, L., Oct 21 2019, In : Clinical Epigenetics. 11, 1, 145.

Research output: Contribution to journalArticle

Open Access
Virus Diseases
DNA Methylation
Hepacivirus
Hepatocellular Carcinoma
Methylation

Enhanced and controlled chromatin extraction from FFPE tissues and the application to ChIP-seq

Zhong, J., Ye, Z., Clark, C. R., Lenz, S. W., Nguyen, J. H., Yan, H. D., Robertson, K. D., Farrugia, G., Zhang, Z., Ordog, T. & Lee, J. H., Mar 29 2019, In : BMC genomics. 20, 1, 249.

Research output: Contribution to journalArticle

Paraffin
Formaldehyde
Chromatin
Epigenomics
Temperature

Erratum to: ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors (Nature Cell Biology, (2017), 19, 9, (1037-1048), 10.1038/ncb3598)

Skamagki, M., Correia, C., Yeung, P., Baslan, T., Beck, S., Zhang, C., Ross, C. A., Dang, L., Liu, Z., Giunta, S., Chang, T. P., Wang, J., Ananthanarayanan, A., Bohndorf, M., Bosbach, B., Adjaye, J., Funabiki, H., Kim, J., Lowe, S., Collins, J. J. & 4 others, Lu, C. W., Li, H., Zhao, R. & Kim, K., Jan 1 2019, (Accepted/In press) In : Nature Cell Biology.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Genomic Instability
Cell Biology
Manuscripts
Information Storage and Retrieval

Genetic predictors of chemotherapy-related amenorrhea in women with breast cancer

Ruddy, K. J., Schaid, D. J., Partridge, A. H., Larson, N. B., Batzler, A., Häberle, L., Dittrich, R., Widschwendter, P., Fink, V., Bauer, E., Schwitulla, J., Rübner, M., Ekici, A. B., Aivazova-Fuchs, V., Stewart, E. A., Beckmann, M. W., Ginsburg, E., Wang, L., Weinshilboum, R. M., Couch, F. J. & 4 others, Janni, W., Rack, B., Vachon, C. & Fasching, P. A., Jan 1 2019, (Accepted/In press) In : Fertility and Sterility.

Research output: Contribution to journalArticle

Amenorrhea
Breast Neoplasms
Drug Therapy
Menstruation
Phosphopantothenoyl-cysteine decarboxylase
2 Citations (Scopus)

Genetic variant in SLC1A2 is associated with elevated anterior cingulate cortex glutamate and lifetime history of rapid cycling

Veldic, M. D., Millischer, V., Port, J. D., Ho, A. M. C., Jia, Y. F., Geske, J. R., Biernacka, J. M., Backlund, L., McElroy, S. L., Bond, D. J., Villaescusa, J. C., Skime, M., Choi, D. S., Lavebratt, C., Schalling, M. & Frye, M. A., Dec 1 2019, In : Translational psychiatry. 9, 1, 149.

Research output: Contribution to journalArticle

Open Access
Gyrus Cinguli
Glutamic Acid
Alleles
Single Nucleotide Polymorphism
Mood Disorders

Genome-wide discovery and validation of diagnostic DNA methylation-based biomarkers for hepatocellular cancer detection in circulating cell free DNA

Hlady, R. A., Zhao, X., Pan, X., Dong Yang, J., Ahmed, F., Antwi, S. O., Giama, N. H., Patel, T., Roberts, L. R., Liu, C. & Robertson, K. D., Jan 1 2019, In : Theranostics. 9, 24, p. 7239-7250 12 p.

Research output: Contribution to journalArticle

Open Access
DNA Methylation
Liver Neoplasms
Hepatocellular Carcinoma
Biomarkers
Genome

Genome-wide DNA methylomic differences between dorsolateral prefrontal and temporal pole cortices of bipolar disorder

Ho, A. M. C., Winham, S. J., Armasu, S. M., Blacker, C. J., Millischer, V., Lavebratt, C., Overholser, J. C., Jurjus, G. J., Dieter, L., Mahajan, G., Rajkowska, G., Vallender, E. J., Stockmeier, C. A., Robertson, K. D., Frye, M. A., Choi, D. S. & Veldic, M., Oct 1 2019, In : Journal of Psychiatric Research. 117, p. 45-54 10 p.

Research output: Contribution to journalArticle

Open Access
Temporal Lobe
Bipolar Disorder
Genome
DNA
Brain
1 Citation (Scopus)
Reward
Ethanol
Neurons
Purinergic P1 Receptors
Optogenetics

In silico DNA methylation analysis identifies potential prognostic biomarkers in type 2 papillary renal cell carcinoma

Yang, M., Hlady, R. A., Zhou, D., Ho, T. H. & Robertson, K. D., Sep 1 2019, In : Cancer medicine. 8, 12, p. 5760-5768 9 p.

Research output: Contribution to journalArticle

Open Access
DNA Methylation
Renal Cell Carcinoma
Computer Simulation
Biomarkers
Methylation
8 Citations (Scopus)

Integrating the Epigenome to Identify Drivers of Hepatocellular Carcinoma

Hlady, R. A., Sathyanarayan, A., Thompson, J. J., Zhou, D., Wu, Q., Pham, K., Lee, J. H., Liu, C. & Robertson, K. D., Jan 1 2019, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Epigenomics
Hepatocellular Carcinoma
Histone Code
dimethylaniline monooxygenase (N-oxide forming)
Liver
Amyloid Plaques
Acetylcholinesterase
Conformations
Alzheimer Disease
Amyloid

Large Chromosomal Rearrangements Yield Biomarkers to Distinguish Low-Risk From Intermediate- and High-Risk Prostate Cancer

Vasmatzis, G., Kosari, F., Murphy, S. J., Terra, S., Kovtun, I. V., Harris, F. R., Zarei, S., Smadbeck, J., Johnson, S. H., Gaitatzes, A. G., Therneau, T. M., Rangel, L. J., Knudson, R. A., Greipp, P. T., Sukov, W. R., Knutson, D. L., Kloft-Nelson, S. M., Karnes, R. J. & Cheville, J., Jan 1 2019, In : Mayo Clinic Proceedings. 94, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Biomarkers
Area Under Curve
Neoplasm Grading
Needle Biopsy
2 Citations (Scopus)

Loss of SETD2 Induces a Metabolic Switch in Renal Cell Carcinoma Cell Lines toward Enhanced Oxidative Phosphorylation

Liu, J., Hanavan, P. D., Kras, K., Ruiz, Y. W., Castle, E. P., Lake, D. F., Chen, X., O'Brien, D., Luo, H., Robertson, K. D., Gu, H. & Ho, T. H., Jan 4 2019, In : Journal of Proteome Research. 18, 1, p. 331-340 10 p.

Research output: Contribution to journalArticle

Oxidative Phosphorylation
Renal Cell Carcinoma
Cells
Switches
Cell Line
1 Citation (Scopus)

Metabolomic signature of exposure and response to citalopram/escitalopram in depressed outpatients

Bhattacharyya, S., Ahmed, A. T., Arnold, M., Liu, D., Luo, C., Zhu, H., Mahmoudiandehkordi, S., Neavin, D., Louie, G., Dunlop, B. W., Frye, M. A., Wang, L., Weinshilboum, R. M., Krishnan, R. R., Rush, A. J. & Kaddurah-Daouk, R., Dec 1 2019, In : Translational psychiatry. 9, 1, 173.

Research output: Contribution to journalArticle

Open Access
Citalopram
Metabolomics
Outpatients
Depression
Pharmaceutical Preparations
1 Citation (Scopus)

Microbial Metabolism Modulates Antibiotic Susceptibility within the Murine Gut Microbiome

Cabral, D. J., Penumutchu, S., Reinhart, E. M., Zhang, C., Korry, B. J., Wurster, J. I., Nilson, R., Guang, A., Sano, W. H., Rowan-Nash, A. D., Li, H. & Belenky, P., Oct 1 2019, In : Cell Metabolism. 30, 4, p. 800-823.e7

Research output: Contribution to journalArticle

Microbiota
Amoxicillin
Anti-Bacterial Agents
proctolin
Polysaccharides

Novel adenosine analog, N6-(4-hydroxybenzyl)-adenosine, dampens alcohol drinking and seeking behaviors

Hong, S. I., Peyton, L., Chern, Y. & Choi, D. S., Jan 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 371, 2, p. 260-267 8 p.

Research output: Contribution to journalArticle

Open Access
Drinking Behavior
Alcohol Drinking
Adenosine
Ethanol
Equilibrative Nucleoside Transporter 1
1 Citation (Scopus)

Optimal Lymph Node Examination and Adjuvant Chemotherapy for Stage I Lung Cancer

Dai, J., Liu, M., Yang, Y., Li, Q., Song, N., Rocco, G., Sihoe, A. D. L., Gonzalez-Rivas, D., Suen, H. C., He, W., Duan, L., Fan, J., Zhao, D., Wang, H., Zhu, Y., Chen, C., Diasio, R. B., Jiang, G., Yang, P. & Zhang, P., Jan 1 2019, In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Lung Neoplasms
Lymph Nodes
Survival
Confidence Intervals
3 Citations (Scopus)

PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy

Tu, X., Qin, B., Zhang, Y., Zhang, C., Kahila, M., Nowsheen, S., Yin, P., Yuan, J., Pei, H., Li, H., Yu, J., Song, Z., Zhou, Q., Zhao, F., Liu, J., Zhang, C., Dong, H. M., Mutter, R. & Lou, Z., Jun 20 2019, In : Molecular Cell. 74, 6, p. 1215-1226.e4

Research output: Contribution to journalArticle

Exosome Multienzyme Ribonuclease Complex
DNA Damage
Radiation
Drug Therapy
Genetic Therapy
2 Citations (Scopus)

Pharmacogenomic next-generation DNA sequencing: Lessons from the identification and functional characterization of variants of unknown significance in CYP2C9 and CYP2C19

Devarajan, S., Moon, I., Ho, M. F., Larson, N., Neavin, D. R., Moyer, A., Black, J. L., Bielinski, S. J., Scherer, S. E., Wang, L. M., Weinshilboum, R. M. & Reid, J. M., Apr 1 2019, In : Drug Metabolism and Disposition. 47, 4, p. 425-435 11 p.

Research output: Contribution to journalArticle

Pharmacogenetics
DNA Sequence Analysis
Cytochrome P-450 Enzyme System
Oxidoreductases
Proteins
5 Citations (Scopus)

Pharmacogenomics-Driven Prediction of Antidepressant Treatment Outcomes: A Machine-Learning Approach With Multi-trial Replication

Athreya, A. P., Neavin, D., Carrillo-Roa, T., Skime, M., Biernacka, J., Frye, M. A., Rush, A. J., Wang, L., Binder, E. B., Iyer, R. K., Weinshilboum, R. M. & Bobo, W. V., Jan 1 2019, In : Clinical pharmacology and therapeutics.

Research output: Contribution to journalArticle

Pharmacogenetics
Serotonin Uptake Inhibitors
Antidepressive Agents
Major Depressive Disorder
Citalopram
3 Citations (Scopus)
Citalopram
Major Depressive Disorder
Cytochrome P-450 CYP2D6
Treatment Failure
Pharmacokinetics

Pilot Study of Metabolomic Clusters as State Markers of Major Depression and Outcomes to CBT Treatment

Bhattacharyya, S., Dunlop, B. W., Mahmoudiandehkordi, S., Ahmed, A. T., Louie, G., Frye, M. A., Weinshilboum, R. M., Krishnan, R. R., Rush, A. J., Mayberg, H. S., Craighead, W. E. & Kaddurah-Daouk, R., Sep 12 2019, In : Frontiers in Neuroscience. 13, 926.

Research output: Contribution to journalArticle

Open Access
Metabolomics
Cognitive Therapy
Major Depressive Disorder
Depression
Therapeutics

Proteomic Profile of a Chronic Binge Ethanol Exposure Model

Starski, P., Peyton, L., Oliveros, A., Heppelmann, C. J., Dasari, S. & Choi, D. S., Sep 6 2019, In : Journal of Proteome Research. 18, 9, p. 3492-3502 11 p.

Research output: Contribution to journalArticle

Impulsive Behavior
Proteomics
Ethanol
Sirolimus
Gyrus Cinguli

Regulostat Inferelator: a novel network biology platform to uncover molecular devices that predetermine cellular response phenotypes

Ung, C. Y., Ghanat Bari, M., Zhang, C., Liang, J., Correia, C. & Li, H., Aug 22 2019, In : Nucleic acids research. 47, 14, p. e82

Research output: Contribution to journalArticle

Open Access
Bioengineering
Phenotype
Equipment and Supplies
Pharmaceutical Preparations
Synthetic Biology

Remote activation of a latent epitope in an autoantigen decoded with simulated b-factors

Pang, Y. P., Moura, M. C., Thompson, G. E., Nelson, D. R., Hummel, A. M., Jenne, D. E., Emerling, D., Volkmuth, W., Robinson, W. H. & Specks, U., Jan 1 2019, In : Frontiers in immunology. 10, OCT, 2467.

Research output: Contribution to journalArticle

Open Access
Autoantigens
Myeloblastin
Granulomatosis with Polyangiitis
Epitopes
Mutation
3 Citations (Scopus)

Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons

Vadodaria, K. C., Ji, Y., Skime, M., Paquola, A., Nelson, T. J., Hall-Flavin, D., Fredlender, C., Heard, K. J., Deng, Y., Le, A. T., Dave, S., Fung, L., Li, X., Marchetto, M. C., Weinshilboum, R. M. & Gage, F. H., Jan 1 2019, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Major Depressive Disorder
Serotonin Uptake Inhibitors
Serotonin
Neurons
Synaptic Transmission
1 Citation (Scopus)

Sex-specific association of depressive disorder and transient emotional states with alcohol consumption in male and female alcoholics

Karpyak, V. M., Geske, J. R., Hall-Flavin, D. K., Loukianova, L. L., Schneekloth, T. D., Skime, M. K., Seppala, M., Dawson, G., Frye, M. A., Choi, D. S. & Biernacka, J. M., Mar 1 2019, In : Drug and Alcohol Dependence. 196, p. 31-39 9 p.

Research output: Contribution to journalArticle

Alcoholics
Depressive Disorder
Alcohol Drinking
Alcohols
Major Depressive Disorder
Open Access
Aryl Hydrocarbon Receptors
Quantitative Trait Loci
Single Nucleotide Polymorphism
Binding Sites
Ligands

T4 extension alone is more predictive of better survival than a tumour size >7 cm for resected T4N0-1M0 non-small-cell lung cancer

Li, Q., Zhang, P., Wang, Y., Liu, D., Luo, L., Diasio, R. B., Yang, P. & Jiang, G., Apr 1 2019, In : European Journal of Cardio-Thoracic Surgery. 55, 4, p. 682-690 9 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Survival
Neoplasms
Comorbidity
Confidence Intervals
1 Citation (Scopus)

Targeted Treatment of Individuals With Psychosis Carrying a Copy Number Variant Containing a Genomic Triplication of the Glycine Decarboxylase Gene

Bodkin, J. A., Coleman, M. J., Godfrey, L. J., Carvalho, C. M. B., Morgan, C. J., Suckow, R. F., Anderson, T., Öngür, D., Kaufman, M. J., Lewandowski, K. E., Siegel, A. J., Waldstreicher, E., Grochowski, C. M., Javitt, D. C., Rujescu, D., Hebbring, S., Weinshilboum, R., Rodriguez, S. B., Kirchhoff, C., Visscher, T. & 11 others, Vuckovic, A., Fialkowski, A., McCarthy, S., Malhotra, D., Sebat, J., Goff, D. C., Hudson, J. I., Lupski, J. R., Coyle, J. T., Rudolph, U. & Levy, D. L., Oct 1 2019, In : Biological psychiatry. 86, 7, p. 523-535 13 p.

Research output: Contribution to journalArticle

Glycine Dehydrogenase (Decarboxylating)
N-Methyl-D-Aspartate Receptors
Psychotic Disorders
Glycine
Cycloserine
2 Citations (Scopus)

The association of obesity and coronary artery disease genes with response to SSRIs treatment in major depression

Amare, A. T., Schubert, K. O., Tekola-Ayele, F., Hsu, Y. H., Sangkuhl, K., Jenkins, G., Whaley, R. M., Barman, P., Batzler, A., Altman, R. B., Arolt, V., Brockmöller, J., Chen, C. H., Domschke, K., Hall-Flavin, D. K., Hong, C. J., Illi, A., Ji, Y., Kampman, O., Kinoshita, T. & 17 others, Leinonen, E., Liou, Y. J., Mushiroda, T., Nonen, S., Skime, M. K., Wang, L. M., Kato, M., Liu, Y. L., Praphanphoj, V., Stingl, J. C., Bobo, W. V., Tsai, S. J., Kubo, M., Klein, T. E., Weinshilboum, R. M., Biernacka, J. M. & Baune, B. T., Jan 1 2019, (Accepted/In press) In : Journal of Neural Transmission.

Research output: Contribution to journalArticle

Serotonin Uptake Inhibitors
Coronary Artery Disease
Obesity
Depression
Genes

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1

Cairns, J., Ingle, J. N., Kalari, K. R., Shepherd, L. E., Kubo, M., Goetz, M. P., Weinshilboum, R. M. & Wang, L. M., Apr 3 2019, In : Breast Cancer Research. 21, 1, 47.

Research output: Contribution to journalArticle

Open Access
Early Growth Response Protein 1
Lemur
Long Noncoding RNA
Aromatase Inhibitors
Protein-Tyrosine Kinases

Type 1 equilibrative nucleoside transporter (ENT1) regulates sex-specific ethanol drinking during disruption of circadian rhythms

Jia, Y. F., Vadnie, C. A., Ho, A. M. C., Peyton, L., Veldic, M. D., Wininger, K., Matveyenko, A. V. & Choi, D. S., Jan 1 2019, In : Addiction Biology. e12801.

Research output: Contribution to journalArticle

Equilibrative Nucleoside Transporter 1
Circadian Rhythm
Drinking
Ethanol
Knockout Mice
6 Citations (Scopus)

UFL1 promotes histone H4 ufmylation and ATM activation

Qin, B., Yu, J., Nowsheen, S., Wang, M., Tu, X., Liu, T., Li, H., Wang, L. M. & Lou, Z., Dec 1 2019, In : Nature communications. 10, 1, 1242.

Research output: Contribution to journalArticle

Open Access
ataxia
Ataxia Telangiectasia
Ligases
Histones
Chemical activation

Waiting impulsivity during reward seeking increases adult hippocampal neurogenesis in mice

Peyton, L., Oliveros, A., Cho, C. H., Starski, P., Lindberg, D., Jang, M-H. D. & Choi, D. S., Jul 27 2019, In : Neuroscience Letters. 706, p. 169-175 7 p.

Research output: Contribution to journalArticle

Impulsive Behavior
Neurogenesis
Reward
Addictive Behavior
Bromodeoxyuridine