Research Output

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Review article
2013

Retromer-mediated endosomal protein sorting: All WASHed up!

Seaman, M. N. J., Gautreau, A. & Billadeau, D. D., Nov 2013, In : Trends in Cell Biology. 23, 11, p. 522-528 7 p.

Research output: Contribution to journalReview article

124 Scopus citations

The elephant and the blind men: Making sense of PARP inhibitors in homologous recombination deficient tumor cells

De Lorenzo, S. B., Patel, A. G., Hurley, R. M. & Kaufmann, S. H., 2013, In : Frontiers in Oncology. 3 SEP, Article 228.

Research output: Contribution to journalReview article

75 Scopus citations
2012

Hormone response in ovarian cancer: Time to reconsider as a clinical target?

Modugno, F., Laskey, R., Smith, A. L., Andersen, C. L., Haluska, P. & Oesterreich, S., Dec 2012, In : Endocrine-Related Cancer. 19, 6, p. R255-R279

Research output: Contribution to journalReview article

68 Scopus citations

The Insulin-Like Growth Factor System in Cancer

Weroha, S. J. & Haluska, P., Jun 2012, In : Endocrinology and Metabolism Clinics of North America. 41, 2, p. 335-350 16 p.

Research output: Contribution to journalReview article

107 Scopus citations
2011

Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors

Comba, A., Lin, Y. H., Eynard, A. R., Valentich, M. A., Fernandez-Zapico, M. E. & Pasqualini, M. E., Dec 2011, In : Cancer and Metastasis Reviews. 30, 3-4, p. 325-342 18 p.

Research output: Contribution to journalReview article

32 Scopus citations

Maintain focus and aim high

Fernández-Zapico, M. E., Mar 2011, In : Pancreatology. 10, 6, p. 657-659 3 p.

Research output: Contribution to journalReview article

The role of FKBP5 in cancer aetiology and chemoresistance

Li, L., Lou, Z. & Wang, L., Jan 4 2011, In : British journal of cancer. 104, 1, p. 19-23 5 p.

Research output: Contribution to journalReview article

56 Scopus citations
2010

Development of PARP inhibitors: An unfinished story

Patel, A. & Kaufmann, S. H., Jan 2010, In : Oncology. 24, 1

Research output: Contribution to journalReview article

11 Scopus citations

Fungal infections in leukemia patients: How do we prevent and treat them?

Leventakos, K., Lewis, R. E. & Kontoyiannis, D. P., Feb 1 2010, In : Clinical Infectious Diseases. 50, 3, p. 405-415 11 p.

Research output: Contribution to journalReview article

Open Access
108 Scopus citations

Prospects for the use of ATR inhibitors to treat cancer

Wagner, J. M. & Kaufmann, S. H., 2010, In : Pharmaceuticals. 3, 5, p. 1311-1334 24 p.

Research output: Contribution to journalReview article

41 Scopus citations

T cell activation at the immunological synapse: Vesicles emerge for later signaling

Billadeau, D. D., May 11 2010, In : Science Signaling. 3, 121, p. pe16

Research output: Contribution to journalReview article

14 Scopus citations
2009

Cixutumumab

McKian, K. P. & Haluska, P., Jul 2009, In : Expert Opinion on Investigational Drugs. 18, 7, p. 1025-1033 9 p.

Research output: Contribution to journalReview article

46 Scopus citations

Immunomodulating effects of antifungal therapy

Leventakos, K., Ben-Ami, R., Lewis, R. E. & Kontoyiannis, D. P., Dec 1 2009, In : Current Fungal Infection Reports. 3, 4, p. 243-250 8 p.

Research output: Contribution to journalReview article

3 Scopus citations

Metastatic malignant melanoma

Markovic, S. N., Erickson, L. A., Flotte, T. J., Kottschade, L. A., Mcwilliams, R. R., Jakub, J. W., Farley, D. R., Tran, N. V., Schild, S. E., Olivier, K. R., Vuk-Pavlovic, S., Sekulic, A., Weenig, R. H., Pulido, J. S., Quevedo, J. F., Vile, R. G., Wiseman, G. A., Stoian, I. & Pittelkow, M. R., Jan 1 2009, In : Giornale Italiano di Dermatologia e Venereologia. 144, 1, p. 1-26 26 p.

Research output: Contribution to journalReview article

7 Scopus citations

p30 DBC is a potential regulator of tumorigenesis

Kim, J. E., Chen, J. & Lou, Z., Sep 15 2009, In : Cell Cycle. 8, 18, p. 2933-2936 4 p.

Research output: Contribution to journalReview article

Open Access
31 Scopus citations

Resistance pathways relevant to insulin-like growth factor-1 receptor-targeted therapy

Hendrickson, A. W. & Haluska, P., Oct 1 2009, In : Current Opinion in Investigational Drugs. 10, 10, p. 1032-1040 9 p.

Research output: Contribution to journalReview article

37 Scopus citations
2008

IGF-1 receptor inhibitors in clinical trials - Early lessons

Weroha, S. J. & Haluska, P., 2008, In : Journal of mammary gland biology and neoplasia. 13, 4, p. 471-483 13 p.

Research output: Contribution to journalReview article

138 Scopus citations

Melanoma-induced brain metastases

McWilliams, R. R., Rao, R. D., Buckner, J. C., Link, M. J., Markovic, S. & Brown, P. D., Aug 28 2008, In : Expert review of anticancer therapy. 8, 5, p. 743-755 13 p.

Research output: Contribution to journalReview article

20 Scopus citations

New therapeutic agents for diabetic kidney disease

Agrawal, V., Kizilbash, S. H. & McCullough, P. A., Aug 13 2008, In : Therapy. 5, 4, p. 553-575 23 p.

Research output: Contribution to journalReview article

4 Scopus citations
2007

Cdc37 regulation of the kinome: when to hold 'em and when to fold 'em.

Karnitz, L. M. & Felts, S. J., May 26 2007, In : Science's STKE : signal transduction knowledge environment. 2007, 385, p. pe22

Research output: Contribution to journalReview article

34 Scopus citations

'Do research with seriousness and perseverance': An interview with Prof. Lucio Gullo

Fernandez-Zapico, M. E., Sep 2007, In : Pancreatology. 7, 4, p. 311-313 3 p.

Research output: Contribution to journalReview article

'Look for the right mentor': An interview with Prof. Manfred V. Singer

Fernandez-Zapico, M. E., May 2007, In : Pancreatology. 7, 1, p. 3-6 4 p.

Research output: Contribution to journalReview article

1 Scopus citations

Regulation of T-cell activation by the cytoskeleton

Billadeau, D. D., Nolz, J. C. & Gomez, T. S., Feb 1 2007, In : Nature Reviews Immunology. 7, 2, p. 131-143 13 p.

Research output: Contribution to journalReview article

244 Scopus citations

'The success of the mentee is the mentor's ultimate reward': An interview with Dr. Michael L. Steer

Fernandez-Zapico, M. E., Mar 2007, In : Pancreatology. 6, 6, p. 507-509 3 p.

Research output: Contribution to journalReview article

'You're heading in the right direction': An interview with Dr. Fred Gorelick

Fernandez-Zapico, M. E., Jul 2007, In : Pancreatology. 7, 2-3, p. 93-95 3 p.

Research output: Contribution to journalReview article

2006

Apoptosis in the treatment of cancer: a promise kept?

Meng, X. W., Lee, S. H. & Kaufmann, S. H., Dec 1 2006, In : Current Opinion in Cell Biology. 18, 6, p. 668-676 9 p.

Research output: Contribution to journalReview article

60 Scopus citations

Cellular senescence and DNA repair

Lou, Z. & Chen, J., Aug 15 2006, In : Experimental Cell Research. 312, 14, p. 2641-2646 6 p.

Research output: Contribution to journalReview article

54 Scopus citations

Genetic analysis of apoptotic execution.

Ruchand, S., Samejima, K., Hudson, D., Kaufmann, S. H. & Earnshaw, W. C., 2006, In : Sub-cellular biochemistry. 40, p. 75-90 16 p.

Research output: Contribution to journalReview article

1 Scopus citations
83 Scopus citations

Key role of Krüppel-like factor proteins in pancreatic cancer and other gastrointestinal neoplasias

Buttar, N. S., Fernandez-Zapico, M. E. & Urrutia, R., Sep 2006, In : Current Opinion in Gastroenterology. 22, 5, p. 505-511 7 p.

Research output: Contribution to journalReview article

11 Scopus citations

Regulation of cytoskeletal dynamics at the immune synapse: New stars join the actin troupe

Billadeau, D. D. & Burkhardt, J. K., Nov 2006, In : Traffic. 7, 11, p. 1451-1460 10 p.

Research output: Contribution to journalReview article

55 Scopus citations

Targeting GSK-3: A promising approach for cancer therapy?

Ougolkov, A. V. & Billadeau, D. D., Feb 1 2006, In : Future Oncology. 2, 1, p. 91-100 10 p.

Research output: Contribution to journalReview article

94 Scopus citations

To understand what happens to the foods that you and i eat: An interview with Dr. Vay Liang Go

Fernandez-Zapico, M. E., Aug 2006, In : Pancreatology. 6, 4, p. 263-265 3 p.

Research output: Contribution to journalReview article

2005

'Good mentorship is invaluable' - An interview with Dr. Eugene P. DiMagno

Fernandez-Zapico, M. E., Jan 1 2005, In : Pancreatology. 5, 1, p. 5-7 3 p.

Research output: Contribution to journalReview article

3 Scopus citations

Novel therapeutics in colorectal cancer

McWilliams, R. R. & Erlichman, C., Aug 1 2005, In : Diseases of the colon and rectum. 48, 8, p. 1632-1650 19 p.

Research output: Contribution to journalReview article

20 Scopus citations

Right place, right time, and only once: Replication initiation in metazoans

Machida, Y. J., Hamlin, J. L. & Dutta, A., Oct 7 2005, In : Cell. 123, 1, p. 13-24 12 p.

Research output: Contribution to journalReview article

227 Scopus citations

Treatment options for brain metastases from melanoma

McWilliams, R. R., Rao, R. D., Brown, P. D., Link, M. J. & Buckner, J. C., Oct 1 2005, In : Expert review of anticancer therapy. 5, 5, p. 809-820 12 p.

Research output: Contribution to journalReview article

11 Scopus citations

When developmental signaling pathways go wrong and their impact on pancreatic cancer development

Lomberk, G., Fernandez-Zapico, M. E. & Urrutia, R., Sep 1 2005, In : Current Opinion in Gastroenterology. 21, 5, p. 555-560 6 p.

Research output: Contribution to journalReview article

6 Scopus citations
2004

Dial 9-1-1 for DNA damage: The Rad9-Hus1-Rad1 (9-1-1) clamp complex

Parrilla-Castellar, E. R., Arlander, S. J. H. & Karnitz, L., Aug 1 2004, In : DNA Repair. 3, 8-9, p. 1009-1014 6 p.

Research output: Contribution to journalReview article

218 Scopus citations

Molecular pathways of pancreatic carcinogenesis

Fernandez-Zapico, M. E. & Urrutia, R., Nov 2004, In : Drug Discovery Today: Disease Mechanisms. 1, 2, p. 247-252 6 p.

Research output: Contribution to journalReview article

6 Scopus citations
2003

Alterations in the apoptotic machinery and their potential role in anticancer drug resistance

Kaufmann, S. H. & Vaux, D. L., Oct 20 2003, In : Oncogene. 22, 47 REV. ISS. 6, p. 7414-7430 17 p.

Research output: Contribution to journalReview article

243 Scopus citations

BRCA proteins and DNA damage checkpoints

Lou, Z. & Chen, J., Jan 1 2003, In : Frontiers in Bioscience. 8, SUPPL., p. s718-s721

Research output: Contribution to journalReview article

9 Scopus citations

Expression profiling in pancreatic cancer research: The initial steps and the road ahead

Fernandez-Zapico, M. E., Callahan, G., Delgado, S. & Urrutia, R., Sep 1 2003, In : Current Opinion in Gastroenterology. 19, 5, p. 467-472 6 p.

Research output: Contribution to journalReview article

Treatment of Brain Metastases from Melanoma

McWilliams, R. R., Brown, P. D., Buckner, J. C., Link, M. J. & Markovic, S. N., Dec 2003, In : Mayo Clinic proceedings. 78, 12, p. 1529-1536 8 p.

Research output: Contribution to journalReview article

Open Access
42 Scopus citations
2002
9 Scopus citations

ITAMs versus ITIMs: Striking a balance during cell regulation

Billadeau, D. D. & Leibson, P. J., 2002, In : Journal of Clinical Investigation. 109, 2, p. 161-168 8 p.

Research output: Contribution to journalReview article

Open Access
141 Scopus citations

Pancreatic cancer research: Challenges, opportunities, and recent developments

Fernandez-Zapico, M. E., Kaczynski, J. A. & Urrutia, R., Sep 1 2002, In : Current Opinion in Gastroenterology. 18, 5, p. 563-567 5 p.

Research output: Contribution to journalReview article

6 Scopus citations

VAV proteins as signal integrators for multi-subunit immune-recognition receptors

Turner, M. & Billadeau, D. D., Jul 1 2002, In : Nature Reviews Immunology. 2, 7, p. 476-486 11 p.

Research output: Contribution to journalReview article

244 Scopus citations
2001

Apoptosis and the response to anticancer therapy

Mow, B. M. F., Blajeski, A. L., Chandra, J. & Kaufmann, S. H., Nov 13 2001, In : Current Opinion in Oncology. 13, 6, p. 453-462 10 p.

Research output: Contribution to journalReview article

80 Scopus citations

Current status of clinical trials of farnesyltransferase inhibitors

Karp, J. E., Kaufmann, S. H., Adjei, A. A., Lancet, J. E., Wright, J. J. & End, D. W., Nov 13 2001, In : Current Opinion in Oncology. 13, 6, p. 470-476 7 p.

Research output: Contribution to journalReview article

119 Scopus citations