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2019

Association of Thyrotropin Suppression With Survival Outcomes in Patients With Intermediate- and High-Risk Differentiated Thyroid Cancer

Klubo-Gwiezdzinska, J., Auh, S., Gershengorn, M., Daley, B., Bikas, A., Burman, K., Wartofsky, L., Urken, M., Dewey, E., Smallridge, R. C., Chindris, A. M. & Kebebew, E., Feb 1 2019, In : JAMA network open. 2, 2, p. e187754

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Comparison of Incident Cardiovascular Event Rates Between Generic and Brand L-Thyroxine for the Treatment of Hypothyroidism

Smallridge, R. C., Sangaralingham, L. R., Mwangi, R., Kusumoto, F., Van Houten, H. & Bernet, V., Jan 1 2019, In : Mayo Clinic proceedings.

Research output: Contribution to journalArticle

Comprehensive genetic characterization of human thyroid cancer cell lines: A validated panel for preclinical studies

Landa, I., Pozdeyev, N., Korch, C., Marlow, L. A., Smallridge, R. C., Copland, J. A. III., Henderson, Y. C., Lai, S. Y., Clayman, G. L., Onoda, N., Tan, A. C., Garcia-Rendueles, M. E. R., Knauf, J. A., Haugen, B. R., Fagin, J. A. & Schweppe, R. E., Jan 1 2019, In : Clinical Cancer Research. 25, 10, p. 3141-3151 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Ethanol ablation of neck metastases from differentiated thyroid carcinoma

Paz-Fumagalli, R., Li, X. & Smallridge, R. C., Jan 1 2019, In : Seminars in Interventional Radiology. 36, 5, p. 381-385 5 p.

Research output: Contribution to journalArticle

2018

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 690-705.e9

Research output: Contribution to journalArticle

77 Scopus citations

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 400-416.e11

Research output: Contribution to journalArticle

192 Scopus citations

A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 386-399.e12

Research output: Contribution to journalArticle

40 Scopus citations

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

The Cancer Genome Atlas Research Network, Oct 24 2018, In : Cell Systems. 7, 4, p. 422-437.e7

Research output: Contribution to journalArticle

20 Scopus citations

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

The Cancer Genome Atlas Network, Apr 5 2018, In : Cell. 173, 2, p. 291-304.e6

Research output: Contribution to journalArticle

215 Scopus citations

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 721-735.e8

Research output: Contribution to journalArticle

57 Scopus citations

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

The Cancer Genome Atlas Research Network, Aug 13 2018, In : Cancer Cell. 34, 2, p. 211-224.e6

Research output: Contribution to journalArticle

83 Scopus citations

Comprehensive Characterization of Cancer Driver Genes and Mutations

The MC3 Working Group & The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 371-385.e18

Research output: Contribution to journalArticle

235 Scopus citations

Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

The Cancer Genome Atlas Research Network, Oct 30 2018, In : Cell Reports. 25, 5, p. 1304-1317.e5

Research output: Contribution to journalArticle

24 Scopus citations

Cytokeratin-8 in anaplastic thyroid carcinoma: More than a simple structural cytoskeletal protein

Guo, D., Xu, Q., Pabla, S., Koomen, J., Biddinger, P., Sharma, A., Pabla, S., Pacholczyk, R., Chang, C. C., Friedrich, K., Mohammed, K., Smallridge, R. C., Copland, J. A. III., She, J. X. & Weinberger, P. M., Feb 14 2018, In : International Journal of Molecular Sciences. 19, 2, 577.

Research output: Contribution to journalArticle

2 Scopus citations

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

The Fusion Analysis Working Group & The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 227-238.e3

Research output: Contribution to journalArticle

70 Scopus citations

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 194-212.e6

Research output: Contribution to journalArticle

44 Scopus citations

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 676-689.e3

Research output: Contribution to journalArticle

76 Scopus citations

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 239-254.e6

Research output: Contribution to journalArticle

111 Scopus citations

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 213-226.e3

Research output: Contribution to journalArticle

17 Scopus citations

lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 706-720.e9

Research output: Contribution to journalArticle

110 Scopus citations

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 172-180.e3

Research output: Contribution to journalArticle

23 Scopus citations

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 338-354.e15

Research output: Contribution to journalArticle

111 Scopus citations

Methodology, Criteria, and Characterization of Patient-Matched Thyroid Cell Lines and Patient-Derived Tumor Xenografts

Marlow, L. A., Rohl, S. D., Miller, J. L., Knauf, J. A., Fagin, J. A., Ryder, M., Milosevic, D., Netzel, B. C., Grebe, S. K., Reddi, H. V., Smallridge, R. C. & Copland, J. A. III., Sep 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 9, p. 3169-3182 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 255-269.e4

Research output: Contribution to journalArticle

23 Scopus citations

Oncogenic Signaling Pathways in The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 321-337.e10

Research output: Contribution to journalArticle

264 Scopus citations

Over-the-Counter “Adrenal Support” Supplements Contain Thyroid and Steroid-Based Adrenal Hormones

Akturk, H. K., Chindris, A. M., Hines, J. M., Singh, R. J. & Bernet, V. J., Mar 1 2018, In : Mayo Clinic Proceedings. 93, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

The Cancer Genome Atlas Network, Mar 28 2018, In : Cell Systems. 6, 3, p. 282-300.e2

Research output: Contribution to journalArticle

42 Scopus citations

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 297-312.e12

Research output: Contribution to journalArticle

73 Scopus citations

Pathogenic Germline Variants in 10,389 Adult Cancers

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 355-370.e14

Research output: Contribution to journalArticle

106 Scopus citations

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 305-320.e10

Research output: Contribution to journalArticle

58 Scopus citations

Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

MC3 Working Group & The Cancer Genome Atlas Research Network, Mar 28 2018, In : Cell Systems. 6, 3, p. 271-281.e7

Research output: Contribution to journalArticle

83 Scopus citations

Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 282-296.e4

Research output: Contribution to journalArticle

57 Scopus citations

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 181-193.e7

Research output: Contribution to journalArticle

85 Scopus citations

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 270-281.e3

Research output: Contribution to journalArticle

36 Scopus citations

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 313-326.e5

Research output: Contribution to journalArticle

85 Scopus citations

The Immune Landscape of Cancer

The Cancer Genome Atlas Research Network, Apr 17 2018, In : Immunity. 48, 4, p. 812-830.e14

Research output: Contribution to journalArticle

370 Scopus citations

Thyroid carcinoma, version 2.2018 featured updates to the NCCN guidelines

Haddad, R. I., Nasr, C., Bischoff, L., Busaidy, N. L., Byrd, D., Callender, G., Dickson, P., Duh, Q. Y., Ehya, H., Goldner, W., Haymart, M., Hoh, C., Hunt, J. P., Iagaru, A., Kandeel, F., Kopp, P., Lamonica, D. M., McIver, B., Raeburn, C. D., Ridge, J. A. & 12 others, Ringel, M. D., Scheri, R. P., Shah, J. P., Sippel, R., Smallridge, R. C., Sturgeon, C., Wang, T. N., Wirth, L. J., Wong, R. J., Johnson-Chilla, A., Hoffmann, K. G. & Gurski, L. A., Dec 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 12, p. 1429-1440 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Thyroseq®V2.0 Molecular testing: A cost-effective approach for the evaluation of indeterminate thyroid nodules

Rivas, A. M., Nassar, A., Zhang, J., Casler, J. D., Chindris, A. M., Smallridge, R. C. & Bernet, V., Sep 1 2018, In : Endocrine Practice. 24, 9, p. 780-788 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
2017

Cell Cycle M-Phase Genes Are Highly Upregulated in Anaplastic Thyroid Carcinoma

Weinberger, P., Ponny, S. R., Xu, H., Bai, S., Smallridge, R. C., Copland, J. A. III. & Sharma, A., Feb 1 2017, In : Thyroid. 27, 2, p. 236-252 17 p.

Research output: Contribution to journalArticle

17 Scopus citations

Comprehensive genomic profiling of a rare thyroid follicular dendritic cell sarcoma

Davila, J. I., Starr, J. S., Attia, S., Wang, C., Knudson, R. A., Necela, B. M., Sarangi, V., Sun, Z. D., Ren, Y., Casler, J. D., Menke, D. M., Oliver, G. R., Joseph, R. W., Copland, J. A. III., Parker, A., Kocher, J-P., Thompson, E. A., Smallridge, R. C. & Asmann, Y., Sep 15 2017, In : Rare Tumors. 9, 2, p. 50-53 4 p., 6834.

Research output: Contribution to journalArticle

1 Scopus citations

Survival in Response to Multimodal Therapy in Anaplastic Thyroid Cancer

Prasongsook, N., Kumar, A., Chintakuntlawar, A., Foote, R. L., Kasperbauer, J., Molina, J. R., Garces, Y. I., Ma, D., Wittich, M. A. N., Rubin, J., Richardson, R., Morris, J., Hay, I. D., Fatourechi, V., McIver, B., Ryder, M., Thompson, G., Grant, C., Richards, M., Sebo, T. J. & 5 others, Rivera, M., Suman, V. J., Jenkins, S. M., Smallridge, R. C. & Bible, K. C., Dec 1 2017, In : The Journal of clinical endocrinology and metabolism. 102, 12, p. 4506-4514 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
2016

A Century of Hyperthyroidism at Mayo Clinic

Smallridge, R. C. & Morris, J. C., Jan 1 2016, In : Mayo Clinic Proceedings. 91, 1, p. e7-e12

Research output: Contribution to journalArticle

Improving the adoption of thyroid cancer clinical practice guidelines

Likhterov, I., Tuttle, R. M., Haser, G. C., Su, H. K., Bergman, D., Alon, E. E., Bernet, V., Brett, E., Cobin, R., Dewey, E. H., Doherty, G., Dos Reis, L. L., Klopper, J., Lee, S. L., Lupo, M. A., Machac, J., Mechanick, J. I., Milas, M., Orloff, L., Randolph, G. & 6 others, Ross, D. S., Rowe, M. E., Smallridge, R. C., Terris, D., Tufano, R. P. & Urken, M. L., 2016, (Accepted/In press) In : Laryngoscope.

Research output: Contribution to journalArticle

7 Scopus citations

Symptomatic ovarian steroid cell tumor not otherwise specified in a post-menopausal woman

Sood, N., Desai, K., Chindris, A. M., Lewis, J. & Dinh, T. A., Jun 29 2016, In : Rare Tumors. 8, 2, p. 69-72 4 p., 6200.

Research output: Contribution to journalArticle

2 Scopus citations
2015

Aberrant lipid metabolism in anaplastic thyroid carcinoma reveals stearoyl CoA desaturase 1 as a novel therapeutic target

Von Roemeling, C. A., Marlow, L. A., Pinkerton, A. B., Crist, A., Miller, J., Tun, H. W., Smallridge, R. C. & Copland, J. A. III., May 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 5, p. E697-E709

Research output: Contribution to journalArticle

39 Scopus citations

Anaplastic thyroid carcinoma, version 2.2015

Haddad, R. I., Lydiatt, W. M., Ball, D. W., Busaidy, N. L., Byrd, D., Callender, G., Dickson, P., Duh, Q. Y., Ehya, H., Haymart, M., Hoh, C., Hunt, J. P., Iagaru, A., Kandeel, F., Kopp, P., Lamonica, D. M., McCaffrey, J. C., Moley, J. F., Parks, L., Raeburn, C. D. & 10 others, Ridge, J. A., Ringel, M. D., Scheri, R. P., Shah, J. P., Smallridge, R. C., Sturgeon, C., Wang, T. N., Wirth, L. J., Hoffmann, K. G. & Hughes, M., Sep 1 2015, In : JNCCN Journal of the National Comprehensive Cancer Network. 13, 9, p. 1140-1150 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

Clinical and molecular features of hürthle cell carcinoma of the thyroid

Chindris, A. M., Casler, J. D., Bernet, V. J., Rivera, M., Thomas, C., Kachergus, J. M., Necela, B. M., Hay, I. D., Westphal, S. A., Grant, C. S., Thompson, G. B., Schlinkert, R. T., Thompson, E. A. & Smallridge, R. C., Jan 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 1, p. 55-62 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Database and registry research in thyroid cancer: Striving for a new and improved national thyroid cancer database

Mehra, S., Tuttle, R. M., Milas, M., Orloff, L., Bergman, D., Bernet, V., Brett, E., Cobin, R., Doherty, G., Judson, B. L., Klopper, J., Lee, S., Lupo, M., Machac, J., Mechanick, J. I., Randolph, G., Ross, D. S., Smallridge, R. C., Terris, D., Tufano, R. & 5 others, Alon, E., Clain, J., Dosreis, L., Scherl, S. & Urken, M. L., Feb 1 2015, In : Thyroid. 25, 2, p. 157-168 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Dual inhibition of HDAC and EGFR signaling with CUDC-101 induces potent suppression of tumor growth and metastasis in anaplastic thyroid cancer

Zhang, L., Zhang, Y., Mehta, A., Boufraqech, M., Davis, S., Wang, J., Tian, Z., Yu, Z., Boxer, M. B., Kiefer, J. A., Copland, J. A. III., Smallridge, R. C., Li, Z., Shen, M. & Kebebew, E., 2015, In : Oncotarget. 6, 11, p. 9073-9085 13 p.

Research output: Contribution to journalArticle

32 Scopus citations

Follicular dendritic cell sarcoma presenting as a thyroid mass

Starr, J. S., Attia, S., Joseph, R. W., Menke, D., Casler, J. & Smallridge, R. C., Jun 10 2015, In : Journal of Clinical Oncology. 33, 17, p. e74-e76

Research output: Contribution to journalArticle

9 Scopus citations