Research Output 1992 2019

2019
1 Citation (Scopus)

Association of Thyrotropin Suppression With Survival Outcomes in Patients With Intermediate- and High-Risk Differentiated Thyroid Cancer

Klubo-Gwiezdzinska, J., Auh, S., Gershengorn, M., Daley, B., Bikas, A., Burman, K., Wartofsky, L., Urken, M., Dewey, E., Smallridge, R. C., Chindris, A. M. & Kebebew, E., Feb 1 2019, In : JAMA network open. 2, 2, p. e187754

Research output: Contribution to journalArticle

Open Access
Thyrotropin
Thyroid Neoplasms
Survival
Disease-Free Survival
Neoplasm Metastasis

Comparison of Incident Cardiovascular Event Rates Between Generic and Brand L-Thyroxine for the Treatment of Hypothyroidism

Smallridge, R. C., Sangaralingham, L. R., Mwangi, R., Kusumoto, F., Van Houten, H. & Bernet, V., Jan 1 2019, In : Mayo Clinic proceedings.

Research output: Contribution to journalArticle

Hypothyroidism
Thyroxine
Atrial Fibrillation
Comorbidity
Hospitalization
8 Citations (Scopus)

Comprehensive genetic characterization of human thyroid cancer cell lines: A validated panel for preclinical studies

Landa, I., Pozdeyev, N., Korch, C., Marlow, L. A., Smallridge, R. C., Copland, J. A. III., Henderson, Y. C., Lai, S. Y., Clayman, G. L., Onoda, N., Tan, A. C., Garcia-Rendueles, M. E. R., Knauf, J. A., Haugen, B. R., Fagin, J. A. & Schweppe, R. E., Jan 1 2019, In : Clinical Cancer Research. 25, 10, p. 3141-3151 11 p.

Research output: Contribution to journalArticle

Medical Genetics
Thyroid Neoplasms
Cell Line
Neoplasms
Mutation
2018
60 Citations (Scopus)

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 690-705.e9

Research output: Contribution to journalArticle

Breast Neoplasms
Atlases
Long Noncoding RNA
Decision Trees
Genome

Anaplastic thyroid cancer

Smallridge, R. C., Casler, J. D. & Menefee, M. E., Sep 17 2018, Practical Management of Thyroid Cancer: A Multidisciplinary Approach. Springer International Publishing, p. 297-305 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Anaplastic Thyroid Carcinoma
117 Citations (Scopus)

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 400-416.e11

Research output: Contribution to journalArticle

Atlases
Genes
Genome
Survival
Neoplasms
30 Citations (Scopus)

A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 386-399.e12

Research output: Contribution to journalArticle

Genes
Tumors
Neoplasms
Computational methods
Chromatin
10 Citations (Scopus)

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

The Cancer Genome Atlas Research Network, Oct 24 2018, In : Cell Systems. 7, 4, p. 422-437.e7

Research output: Contribution to journalArticle

Transforming Growth Factors
Neoplasms
Sequence Deletion
Genes
Gastrointestinal Neoplasms
148 Citations (Scopus)

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

The Cancer Genome Atlas Network, Apr 5 2018, In : Cell. 173, 2, p. 291-304.e6

Research output: Contribution to journalArticle

Tumors
Tissue
Histology
Methylation
Oncology
45 Citations (Scopus)

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 721-735.e8

Research output: Contribution to journalArticle

Adenocarcinoma
Neoplasms
Genome
Chromosomal Instability
Rectum
50 Citations (Scopus)

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

The Cancer Genome Atlas Research Network, Aug 13 2018, In : Cancer Cell. 34, 2, p. 211-224.e6

Research output: Contribution to journalArticle

Alternative Splicing
Neoplasms
Exons
Exome
Peptides
177 Citations (Scopus)

Comprehensive Characterization of Cancer Driver Genes and Mutations

The MC3 Working Group & The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 371-385.e18

Research output: Contribution to journalArticle

Neoplasm Genes
Tumors
Genes
Mutation
Neoplasms
12 Citations (Scopus)

Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

The Cancer Genome Atlas Research Network, Oct 30 2018, In : Cell Reports. 25, 5, p. 1304-1317.e5

Research output: Contribution to journalArticle

Genes
Neoplasms
Squamous Cell Neoplasms
Tumors
Atlases
2 Citations (Scopus)

Cytokeratin-8 in anaplastic thyroid carcinoma: More than a simple structural cytoskeletal protein

Guo, D., Xu, Q., Pabla, S., Koomen, J., Biddinger, P., Sharma, A., Pabla, S., Pacholczyk, R., Chang, C. C., Friedrich, K., Mohammed, K., Smallridge, R. C., Copland, J. A. III., She, J. X. & Weinberger, P. M., Feb 14 2018, In : International Journal of Molecular Sciences. 19, 2, 577.

Research output: Contribution to journalArticle

Keratin-8
keratins
Keratin
Cytoskeletal Proteins
cancer
51 Citations (Scopus)

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

The Fusion Analysis Working Group & The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 227-238.e3

Research output: Contribution to journalArticle

Human Development
Phosphotransferases
Genes
Gene expression
Tumors
13 Citations (Scopus)

Erratum: The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma (Cell Reports (2018) 23(1) (313–326.e5) (S2211124718304364) (10.1016/j.celrep.2018.03.075))

The Cancer Genome Atlas Research Network & The Cancer Genome Atlas Research Network, Jun 19 2018, In : Cell Reports. 23, 12, 1 p.

Research output: Contribution to journalComment/debate

Atlases
Renal Cell Carcinoma
Names
Emotions
Genes
32 Citations (Scopus)

Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

The MC3 Working Group & The Cancer Genome Atlas Research Network, Aug 9 2018, In : Cell. 174, 4, p. 1034-1035 2 p.

Research output: Contribution to journalComment/debate

Neoplasm Genes
Adenocarcinoma
Genes
Mutation
ethyl-2-methylthio-4-methyl-5-pyrimidine carboxylate
35 Citations (Scopus)

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 194-212.e6

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
MicroRNAs
Mutation
Epithelial Cells
Squamous Cell Neoplasms
55 Citations (Scopus)

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 676-689.e3

Research output: Contribution to journalArticle

Aneuploidy
Chromosomes
Neoplasms
Genome
Mutation Rate
83 Citations (Scopus)

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 239-254.e6

Research output: Contribution to journalArticle

DNA Repair-Deficiency Disorders
Atlases
DNA Damage
Repair
Genes
13 Citations (Scopus)

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 213-226.e3

Research output: Contribution to journalArticle

Ubiquitin
Genes
Neoplasms
Tumors
Amplification
90 Citations (Scopus)

lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 706-720.e9

Research output: Contribution to journalArticle

Long Noncoding RNA
Epigenomics
Cell Cycle
Genes
Neoplasms
19 Citations (Scopus)

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 172-180.e3

Research output: Contribution to journalArticle

Atlases
Learning systems
Tumors
Genes
Chemical activation
85 Citations (Scopus)

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 338-354.e15

Research output: Contribution to journalArticle

Learning systems
Tumors
Neoplasms
Stem cells
Logistics
5 Citations (Scopus)

Methodology, Criteria, and Characterization of Patient-Matched Thyroid Cell Lines and Patient-Derived Tumor Xenografts

Marlow, L. A., Rohl, S. D., Miller, J. L., Knauf, J. A., Fagin, J. A., Ryder, M., Milosevic, D., Netzel, B. C., Grebe, S. K., Reddi, H. V., Smallridge, R. C. & Copland, J. A. III., Sep 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 9, p. 3169-3182 14 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Heterografts
Tumors
Thyroid Gland
Cells
20 Citations (Scopus)

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 255-269.e4

Research output: Contribution to journalArticle

Tumors
Carbohydrates
Oncology
Metabolism
Vitamins
189 Citations (Scopus)

Oncogenic Signaling Pathways in The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 321-337.e10

Research output: Contribution to journalArticle

Atlases
Tumors
Genes
Genome
Neoplasms
3 Citations (Scopus)

Over-the-Counter “Adrenal Support” Supplements Contain Thyroid and Steroid-Based Adrenal Hormones

Akturk, H. K., Chindris, A. M., Hines, J. M., Singh, R. J. & Bernet, V. J., Mar 1 2018, In : Mayo Clinic Proceedings. 93, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

Tablets
Thyroid Gland
Steroids
Budesonide
Pregnenolone
33 Citations (Scopus)

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

The Cancer Genome Atlas Network, Mar 28 2018, In : Cell Systems. 6, 3, p. 282-300.e2

Research output: Contribution to journalArticle

Atlases
Oncogenes
Genome
Neoplasms
Neoplasm Genes
56 Citations (Scopus)

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 297-312.e12

Research output: Contribution to journalArticle

Long Noncoding RNA
Neoplasm Genes
Tumors
Genes
Neoplasms
84 Citations (Scopus)

Pathogenic Germline Variants in 10,389 Adult Cancers

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 355-370.e14

Research output: Contribution to journalArticle

Gene expression
Automatic teller machines
Tumors
Neoplasms
Genes
42 Citations (Scopus)

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 305-320.e10

Research output: Contribution to journalArticle

Genomics
Tumors
Genes
Neoplasms
Atlases
57 Citations (Scopus)

Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

MC3 Working Group & The Cancer Genome Atlas Research Network, Mar 28 2018, In : Cell Systems. 6, 3, p. 271-281.e7

Research output: Contribution to journalArticle

Exome
Mutation
Atlases
Neoplasms
Genomics
41 Citations (Scopus)

Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 282-296.e4

Research output: Contribution to journalArticle

Genes
Mutation
Neoplasms
Tumors
RNA
59 Citations (Scopus)

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 181-193.e7

Research output: Contribution to journalArticle

Tumor-Infiltrating Lymphocytes
Lymphocytes
Pathology
Tumors
Learning
28 Citations (Scopus)

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 270-281.e3

Research output: Contribution to journalArticle

Tumors
Mutation
Neoplasms
Bioelectric potentials
Bioinformatics
61 Citations (Scopus)

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 313-326.e5

Research output: Contribution to journalArticle

Atlases
Renal Cell Carcinoma
Genes
Cells
Genome
268 Citations (Scopus)

The Immune Landscape of Cancer

The Cancer Genome Atlas Research Network, Apr 17 2018, In : Immunity. 48, 4, p. 812-830.e14

Research output: Contribution to journalArticle

Neoplasms
Genetic Epigenesis
Lymphocytes
Th2 Cells
Th1 Cells
9 Citations (Scopus)

Thyroid carcinoma, version 2.2018 featured updates to the NCCN guidelines

Haddad, R. I., Nasr, C., Bischoff, L., Busaidy, N. L., Byrd, D., Callender, G., Dickson, P., Duh, Q. Y., Ehya, H., Goldner, W., Haymart, M., Hoh, C., Hunt, J. P., Iagaru, A., Kandeel, F., Kopp, P., Lamonica, D. M., McIver, B., Raeburn, C. D., Ridge, J. A. & 12 others, Ringel, M. D., Scheri, R. P., Shah, J. P., Sippel, R., Smallridge, R. C., Sturgeon, C., Wang, T. N., Wirth, L. J., Wong, R. J., Johnson-Chilla, A., Hoffmann, K. G. & Gurski, L. A., Dec 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 12, p. 1429-1440 12 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Guidelines
Carcinoma, Papillary, Follicular
Medullary Carcinoma
Carcinoma
4 Citations (Scopus)

Thyroseq®V2.0 Molecular testing: A cost-effective approach for the evaluation of indeterminate thyroid nodules

Rivas, A. M., Nassar, A., Zhang, J., Casler, J. D., Chindris, A. M., Smallridge, R. C. & Bernet, V., Sep 1 2018, In : Endocrine Practice. 24, 9, p. 780-788 9 p.

Research output: Contribution to journalArticle

Thyroid Nodule
Costs and Cost Analysis
Thyroidectomy
Thyroid Gland
Thyroid Neoplasms
2017
11 Citations (Scopus)

Cell Cycle M-Phase Genes Are Highly Upregulated in Anaplastic Thyroid Carcinoma

Weinberger, P., Ponny, S. R., Xu, H., Bai, S., Smallridge, R. C., Copland, J. A. III. & Sharma, A., Feb 1 2017, In : Thyroid. 27, 2, p. 236-252 17 p.

Research output: Contribution to journalArticle

Cell Division
Cell Cycle
Genes
Gene Expression
Anaplastic Thyroid Carcinoma
1 Citation (Scopus)

Comprehensive genomic profiling of a rare thyroid follicular dendritic cell sarcoma

Davila, J. I., Starr, J. S., Attia, S., Wang, C., Knudson, R. A., Necela, B. M., Sarangi, V., Sun, Z. D., Ren, Y., Casler, J. D., Menke, D. M., Oliver, G. R., Joseph, R. W., Copland, J. A. III., Parker, A., Kocher, J-P., Thompson, E. A., Smallridge, R. C. & Asmann, Y., Sep 15 2017, In : Rare Tumors. 9, 2, p. 50-53 4 p., 6834.

Research output: Contribution to journalArticle

Follicular Dendritic Cell Sarcoma
Missense Mutation
Mutation
Gene Fusion
Neoplasms

Rapidly enlarging thyroid mass in a patient with history of multiple cancers

Akturk, H. K., Smallridge, R. C. & Casler, J., Jun 1 2017, In : JAMA oncology. 3, 6, p. 853-854 2 p.

Research output: Contribution to journalComment/debate

Thyroid Gland
Neoplasms
19 Citations (Scopus)

Survival in Response to Multimodal Therapy in Anaplastic Thyroid Cancer

Prasongsook, N., Kumar, A., Chintakuntlawar, A., Foote, R. L., Kasperbauer, J., Molina, J. R., Garces, Y. I., Ma, D., Wittich, M. A. N., Rubin, J., Richardson, R., Morris, J., Hay, I. D., Fatourechi, V., McIver, B., Ryder, M., Thompson, G., Grant, C., Richards, M., Sebo, T. J. & 5 others, Rivera, M., Suman, V. J., Jenkins, S. M., Smallridge, R. C. & Bible, K. C., Dec 1 2017, In : The Journal of clinical endocrinology and metabolism. 102, 12, p. 4506-4514 9 p.

Research output: Contribution to journalArticle

Hazards
Survival
Palliative Care
Confidence Intervals
Therapeutics
2016

A case of multifocal papillary thyroid microcarcinoma

Bernet, V. J. & Chindris, A. M., Jan 1 2016, Thyroid Cancer: A Case-Based Approach. Springer International Publishing, p. 51-59 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Papillary Thyroid Microcarcinoma

A Century of Hyperthyroidism at Mayo Clinic

Smallridge, R. C. & Morris, J. C., Jan 1 2016, In : Mayo Clinic Proceedings. 91, 1, p. e7-e12

Research output: Contribution to journalArticle

21st Century History
19th Century History
20th Century History
Hyperthyroidism
Disease Management
25 Citations (Scopus)

Active surveillance for papillary thyroid microcarcinoma: New challenges and opportunities for the health care system

Haser, G. C., Tuttle, R. M., Su, H. K., Alon, E. E., Bergman, D., Bernet, V., Brett, E., Cobin, R., Dewey, E. H., Doherty, G., Dos Reis, L. L., Harris, J., Klopper, J., Lee, S. L., Levine, R. A., Lepore, S. J., Likhterov, I., Lupo, M. A., Machac, J., Mechanick, J. I. & 12 others, Mehra, S., Milas, M., Orloff, L. A., Randolph, G., Revenson, T. A., Roberts, K. J., Ross, D. S., Rowe, M. E., Smallridge, R. C., Terris, D., Tufano, R. P. & Urken, M. L., 2016, In : Endocrine Practice. 22, 5, p. 62-611 550 p.

Research output: Contribution to journalReview article

Delivery of Health Care
Thyroid Gland
Quality of Life
Psychology
Papillary Thyroid Microcarcinoma

Anaplastic thyroid cancer: Surgery or not in locally advanced disease

Smallridge, R. C. & Bible, K. C., Jan 1 2016, Thyroid Cancer: A Case-Based Approach. Springer International Publishing, p. 413-420 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Anaplastic Thyroid Carcinoma
7 Citations (Scopus)

Improving the adoption of thyroid cancer clinical practice guidelines

Likhterov, I., Tuttle, R. M., Haser, G. C., Su, H. K., Bergman, D., Alon, E. E., Bernet, V., Brett, E., Cobin, R., Dewey, E. H., Doherty, G., Dos Reis, L. L., Klopper, J., Lee, S. L., Lupo, M. A., Machac, J., Mechanick, J. I., Milas, M., Orloff, L., Randolph, G. & 6 others, Ross, D. S., Rowe, M. E., Smallridge, R. C., Terris, D., Tufano, R. P. & Urken, M. L., 2016, (Accepted/In press) In : Laryngoscope.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Practice Guidelines
Point-of-Care Systems
Patient Care Management
Guideline Adherence
2 Citations (Scopus)

Symptomatic ovarian steroid cell tumor not otherwise specified in a post-menopausal woman

Sood, N., Desai, K., Chindris, A. M., Lewis, J. & Dinh, T. A., Jun 29 2016, In : Rare Tumors. 8, 2, p. 69-72 4 p., 6200.

Research output: Contribution to journalArticle

Testosterone
Steroids
Ovary
Neoplasms
Sex Cord-Gonadal Stromal Tumors