Waldenstrom macroglobulinemia cells devoid of BTK C481S or CXCR4 WHIM-like mutations acquire resistance to ibrutinib through upregulation of Bcl-2 and AKT resulting in vulnerability towards venetoclax or MK2206 treatment

A. Paulus, S. Akhtar, H. Yousaf, A. Manna, S. M. Paulus, Y. Bashir, T. R. Caulfield, M. Kuranz-Blake, K. Chitta, X. Wang, Y. Asmann, R. Hudec, W. Springer, S. Ailawadhi, A. Chanan-Khan

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