Vulvar Crohn's Disease: Clinical Features and Outcomes

Janice M. Cho; Edward V. Loftus; David H. Bruining; Victor G. Chedid; Francis A. Farraye; William A. Faubion; Amanda M. Johnson; Sunanda V. Kane; John B. Kisiel; Talha A. Malik; Konstantinos A. Papadakis; Darrell S. Pardi; Michael F. Picco; Laura E. Raffals; Kenneth W. Schroeder; William J. Tremaine; Nayantara Coelho-Prabhu

doi:10.14309/ajg.0000000000001502

Vulvar Crohn's Disease: Clinical Features and Outcomes

Janice M. Cho, Edward V. Loftus, David H. Bruining, Victor G. Chedid, Francis A. Farraye, William A. Faubion, Amanda M. Johnson, Sunanda V. Kane, John B. Kisiel, Talha A. Malik, Konstantinos A. Papadakis, Darrell S. Pardi, Michael F. Picco, Laura E. Raffals, Kenneth W. Schroeder, William J. Tremaine, Nayantara Coelho-Prabhu

Research output: Contribution to journal › Article › peer-review

Abstract

INTRODUCTION:Vulvar involvement is a rare complication of Crohn's disease (CD). The optimal treatment of vulvar CD is unknown.METHODS:We conducted a 25-year retrospective cohort study of vulvar CD from 3 referral centers. Clinical features and outcomes were studied.RESULTS:Fifty patients were identified. The most common vulvar symptoms were pain (74%), edema (60%), ulcerations (46%), nodules (36%), and abscess (34%). Medical management leading to symptomatic improvement varied, and 5 patients ultimately required surgery.DISCUSSION:Vulvar CD manifests with a broad spectrum of symptoms. Aggressive medical management was frequently effective, although surgery was required in 10% of cases.

Original language	English (US)
Pages (from-to)	2296-2299
Number of pages	4
Journal	American Journal of Gastroenterology
Volume	116
Issue number	11
DOIs	https://doi.org/10.14309/ajg.0000000000001502
State	Published - Nov 1 2021

ASJC Scopus subject areas

Hepatology
Gastroenterology

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Cho, J. M., Loftus, E. V., Bruining, D. H., Chedid, V. G., Farraye, F. A., Faubion, W. A., Johnson, A. M., Kane, S. V., Kisiel, J. B., Malik, T. A., Papadakis, K. A., Pardi, D. S., Picco, M. F., Raffals, L. E., Schroeder, K. W., Tremaine, W. J., & Coelho-Prabhu, N. (2021). Vulvar Crohn's Disease: Clinical Features and Outcomes. American Journal of Gastroenterology, 116(11), 2296-2299. https://doi.org/10.14309/ajg.0000000000001502

Cho, JM, Loftus, EV, Bruining, DH, Chedid, VG, Farraye, FA, Faubion, WA, Johnson, AM, Kane, SV, Kisiel, JB, Malik, TA, Papadakis, KA, Pardi, DS, Picco, MF, Raffals, LE, Schroeder, KW, Tremaine, WJ & Coelho-Prabhu, N 2021, 'Vulvar Crohn's Disease: Clinical Features and Outcomes', American Journal of Gastroenterology, vol. 116, no. 11, pp. 2296-2299. https://doi.org/10.14309/ajg.0000000000001502

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title = "Vulvar Crohn's Disease: Clinical Features and Outcomes",

abstract = "INTRODUCTION:Vulvar involvement is a rare complication of Crohn's disease (CD). The optimal treatment of vulvar CD is unknown.METHODS:We conducted a 25-year retrospective cohort study of vulvar CD from 3 referral centers. Clinical features and outcomes were studied.RESULTS:Fifty patients were identified. The most common vulvar symptoms were pain (74%), edema (60%), ulcerations (46%), nodules (36%), and abscess (34%). Medical management leading to symptomatic improvement varied, and 5 patients ultimately required surgery.DISCUSSION:Vulvar CD manifests with a broad spectrum of symptoms. Aggressive medical management was frequently effective, although surgery was required in 10% of cases.",

author = "Cho, {Janice M.} and Loftus, {Edward V.} and Bruining, {David H.} and Chedid, {Victor G.} and Farraye, {Francis A.} and Faubion, {William A.} and Johnson, {Amanda M.} and Kane, {Sunanda V.} and Kisiel, {John B.} and Malik, {Talha A.} and Papadakis, {Konstantinos A.} and Pardi, {Darrell S.} and Picco, {Michael F.} and Raffals, {Laura E.} and Schroeder, {Kenneth W.} and Tremaine, {William J.} and Nayantara Coelho-Prabhu",

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doi = "10.14309/ajg.0000000000001502",

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T1 - Vulvar Crohn's Disease

T2 - Clinical Features and Outcomes

AU - Cho, Janice M.

AU - Loftus, Edward V.

AU - Bruining, David H.

AU - Chedid, Victor G.

AU - Farraye, Francis A.

AU - Faubion, William A.

AU - Johnson, Amanda M.

AU - Kane, Sunanda V.

AU - Kisiel, John B.

AU - Malik, Talha A.

AU - Papadakis, Konstantinos A.

AU - Pardi, Darrell S.

AU - Picco, Michael F.

AU - Raffals, Laura E.

AU - Schroeder, Kenneth W.

AU - Tremaine, William J.

AU - Coelho-Prabhu, Nayantara

PY - 2021/11/1

Y1 - 2021/11/1

N2 - INTRODUCTION:Vulvar involvement is a rare complication of Crohn's disease (CD). The optimal treatment of vulvar CD is unknown.METHODS:We conducted a 25-year retrospective cohort study of vulvar CD from 3 referral centers. Clinical features and outcomes were studied.RESULTS:Fifty patients were identified. The most common vulvar symptoms were pain (74%), edema (60%), ulcerations (46%), nodules (36%), and abscess (34%). Medical management leading to symptomatic improvement varied, and 5 patients ultimately required surgery.DISCUSSION:Vulvar CD manifests with a broad spectrum of symptoms. Aggressive medical management was frequently effective, although surgery was required in 10% of cases.

AB - INTRODUCTION:Vulvar involvement is a rare complication of Crohn's disease (CD). The optimal treatment of vulvar CD is unknown.METHODS:We conducted a 25-year retrospective cohort study of vulvar CD from 3 referral centers. Clinical features and outcomes were studied.RESULTS:Fifty patients were identified. The most common vulvar symptoms were pain (74%), edema (60%), ulcerations (46%), nodules (36%), and abscess (34%). Medical management leading to symptomatic improvement varied, and 5 patients ultimately required surgery.DISCUSSION:Vulvar CD manifests with a broad spectrum of symptoms. Aggressive medical management was frequently effective, although surgery was required in 10% of cases.

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Vulvar Crohn's Disease: Clinical Features and Outcomes

Abstract

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