Virus-associated hemophagocytic syndrome following bone marrow transplantation

David A. Reardon; Rudolph Roskos; Curtis A. Hanson; Valerie Castle

doi:10.1097/00043426-199123000-00010

Virus-associated hemophagocytic syndrome following bone marrow transplantation

David A. Reardon, Rudolph Roskos, Curtis A. Hanson, Valerie Castle

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Multiple-organ infiltration by mature, benign erythrophagocytic histiocytes is the pathologic hallmark of the virus-associated hemophagocytic syndrome (VAHS). Although VAHS has been described in a number of clinical settings, it has been reported following bone marrow transplantation (BMT) only once previously. Our report identifies the clinical and laboratory features associated with VAHS and compares the immune defects described in VAHS with those known to occur following BMT.

Original language	English (US)
Pages (from-to)	305-309
Number of pages	5
Journal	Journal of Pediatric Hematology/Oncology
Volume	13
Issue number	3
DOIs	https://doi.org/10.1097/00043426-199123000-00010
State	Published - 1991

Keywords

Bone marrow transplantation
Graft-versus-host disease
Immunodeficiency
Natural killer cells
Virus-associated hemophagocytic syndrome

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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10.1097/00043426-199123000-00010

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title = "Virus-associated hemophagocytic syndrome following bone marrow transplantation",

abstract = "Multiple-organ infiltration by mature, benign erythrophagocytic histiocytes is the pathologic hallmark of the virus-associated hemophagocytic syndrome (VAHS). Although VAHS has been described in a number of clinical settings, it has been reported following bone marrow transplantation (BMT) only once previously. Our report identifies the clinical and laboratory features associated with VAHS and compares the immune defects described in VAHS with those known to occur following BMT.",

keywords = "Bone marrow transplantation, Graft-versus-host disease, Immunodeficiency, Natural killer cells, Virus-associated hemophagocytic syndrome",

author = "Reardon, {David A.} and Rudolph Roskos and Hanson, {Curtis A.} and Valerie Castle",

year = "1991",

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volume = "13",

pages = "305--309",

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T1 - Virus-associated hemophagocytic syndrome following bone marrow transplantation

AU - Reardon, David A.

AU - Roskos, Rudolph

AU - Hanson, Curtis A.

AU - Castle, Valerie

PY - 1991

Y1 - 1991

N2 - Multiple-organ infiltration by mature, benign erythrophagocytic histiocytes is the pathologic hallmark of the virus-associated hemophagocytic syndrome (VAHS). Although VAHS has been described in a number of clinical settings, it has been reported following bone marrow transplantation (BMT) only once previously. Our report identifies the clinical and laboratory features associated with VAHS and compares the immune defects described in VAHS with those known to occur following BMT.

AB - Multiple-organ infiltration by mature, benign erythrophagocytic histiocytes is the pathologic hallmark of the virus-associated hemophagocytic syndrome (VAHS). Although VAHS has been described in a number of clinical settings, it has been reported following bone marrow transplantation (BMT) only once previously. Our report identifies the clinical and laboratory features associated with VAHS and compares the immune defects described in VAHS with those known to occur following BMT.

KW - Bone marrow transplantation

KW - Graft-versus-host disease

KW - Immunodeficiency

KW - Natural killer cells

KW - Virus-associated hemophagocytic syndrome

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Virus-associated hemophagocytic syndrome following bone marrow transplantation

Abstract

Keywords

ASJC Scopus subject areas

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