Ventricular-Arterial Interaction in Patients With Heart Failure and a Preserved Ejection Fraction

Yogesh N.V. Reddy, Barry A. Borlaug, Vojtech Melenovsky

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Abnormalities in vascular stiffness and their coupling with ventricular systolic and diastolic performance contribute to exercise intolerance and symptom manifestation in heart failure with preserved ejection fraction (HFpEF). In this chapter, we will discuss the physiology of normal and abnormal ventricular-vascular coupling and how it relates to HFpEF.

Original languageEnglish (US)
Title of host publicationDiastology
Subtitle of host publicationClinical Approach to Heart Failure with Preserved Ejection Fraction
PublisherElsevier
Pages71-85
Number of pages15
ISBN (Electronic)9780323640671
DOIs
StatePublished - Jan 1 2020

Keywords

  • Afterload
  • Effective arterial elastance
  • End-systolic elastance
  • Exercise capacity
  • Heart failure with preserved ejection fraction
  • Pulsatile load
  • Vascular stiffness

ASJC Scopus subject areas

  • General Medicine

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