Vascular versus myocardial dysfunction in acute coronary syndrome: Are the adhesion molecules as powerful as NT-proBNP for long-term risk stratification?

Peter A. Kavsak, Dennis T. Ko, Alice M. Newman, Viliam Lustig, Glenn E. Palomaki, Andrew R. MacRae, Allan S Jaffe

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objectives: To determine if elevations of adhesion molecules in acute coronary syndrome (ACS) are useful for risk stratification. Design and methods: A cell adhesion array (Randox Ltd.) and NT-proBNP were measured in 216 ACS patients. Results: Kaplan-Meier and Cox models indicate early elevations of NT-proBNP but not the adhesion molecules are predictive of future death/myocardial infarction. Discussion: Elevations of adhesion molecules early after pain onset in ACS are not useful for long-term risk stratification.

Original languageEnglish (US)
Pages (from-to)436-439
Number of pages4
JournalClinical Biochemistry
Volume41
Issue number6
DOIs
StatePublished - Apr 2008

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Acute Coronary Syndrome
Blood Vessels
Adhesion
Molecules
Cell adhesion
Proportional Hazards Models
Cell Adhesion
Myocardial Infarction
Pain
pro-brain natriuretic peptide (1-76)

Keywords

  • ACS
  • Cell adhesion
  • Death
  • MI
  • NT-proBNP

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Vascular versus myocardial dysfunction in acute coronary syndrome : Are the adhesion molecules as powerful as NT-proBNP for long-term risk stratification? / Kavsak, Peter A.; Ko, Dennis T.; Newman, Alice M.; Lustig, Viliam; Palomaki, Glenn E.; MacRae, Andrew R.; Jaffe, Allan S.

In: Clinical Biochemistry, Vol. 41, No. 6, 04.2008, p. 436-439.

Research output: Contribution to journalArticle

Kavsak, Peter A. ; Ko, Dennis T. ; Newman, Alice M. ; Lustig, Viliam ; Palomaki, Glenn E. ; MacRae, Andrew R. ; Jaffe, Allan S. / Vascular versus myocardial dysfunction in acute coronary syndrome : Are the adhesion molecules as powerful as NT-proBNP for long-term risk stratification?. In: Clinical Biochemistry. 2008 ; Vol. 41, No. 6. pp. 436-439.
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