Varicella-zoster virus detection by polymerase chain reaction using bronchoalveolar lavage specimens

Clayton T. Cowl, Udaya B.S. Prakash, P. Shawn Mitchell, Michael R. Migden

Research output: Contribution to journalReview article

14 Scopus citations

Abstract

We report the use of polymerase chain reaction (PCR) techniques from a bronchoalveolar lavage (BAL) specimen for the successful early diagnosis in a case of atypical but severe varicella-zoster virus (VZV) pneumonitis. Atypical presentations of disseminated VZV frequently prolong the time required for accurate diagnosis, resulting in increased morbidity, or mortality. Although further investigation is necessary to determine the sensitivity and positive predictive value of this test, PCR analysis of bronchoscopic specimens may expedite the diagnosis of disseminated VZV.

Original languageEnglish (US)
Pages (from-to)753-754
Number of pages2
JournalAmerican journal of respiratory and critical care medicine
Volume162
Issue number2 I
DOIs
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

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