Use of gene markers to guide antihypertensive therapy

Stephen T. Turner; Gary L. Schwartz; Arlene B. Chapman; Eric Boerwinkle

doi:10.1007/s11906-001-0059-x

Use of gene markers to guide antihypertensive therapy

Stephen T. Turner, Gary L. Schwartz, Arlene B. Chapman, Eric Boerwinkle

Nephrology and Hypertension

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Sequencing of the human genome has elevated the potential for genetic information to aid in the prevention, diagnosis, and treatment of common chronic diseases. One beneficial application of genetic information is the identification of variants that influence response to pharmaceutical agents used to lower blood pressure and prevent target organ complications of hypertension. Knowledge of genetic variants that influence blood pressure response to antihypertensive drugs may allow more individualized tailoring of antihypertensive drug therapy, and provide greater insight into the molecular mechanisms regulating blood pressure levels and causing hypertension.

Original language	English (US)
Pages (from-to)	410-415
Number of pages	6
Journal	Current Hypertension Reports
Volume	3
Issue number	5
DOIs	https://doi.org/10.1007/s11906-001-0059-x
State	Published - 2001

ASJC Scopus subject areas

Internal Medicine

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10.1007/s11906-001-0059-x

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title = "Use of gene markers to guide antihypertensive therapy",

abstract = "Sequencing of the human genome has elevated the potential for genetic information to aid in the prevention, diagnosis, and treatment of common chronic diseases. One beneficial application of genetic information is the identification of variants that influence response to pharmaceutical agents used to lower blood pressure and prevent target organ complications of hypertension. Knowledge of genetic variants that influence blood pressure response to antihypertensive drugs may allow more individualized tailoring of antihypertensive drug therapy, and provide greater insight into the molecular mechanisms regulating blood pressure levels and causing hypertension.",

author = "Turner, {Stephen T.} and Schwartz, {Gary L.} and Chapman, {Arlene B.} and Eric Boerwinkle",

note = "Funding Information: This work was supported by US Public Health Service grants R01 HL53330, U10 HL54464, and funds from the Mayo Foundation.",

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AU - Turner, Stephen T.

AU - Schwartz, Gary L.

AU - Chapman, Arlene B.

AU - Boerwinkle, Eric

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PY - 2001

Y1 - 2001

N2 - Sequencing of the human genome has elevated the potential for genetic information to aid in the prevention, diagnosis, and treatment of common chronic diseases. One beneficial application of genetic information is the identification of variants that influence response to pharmaceutical agents used to lower blood pressure and prevent target organ complications of hypertension. Knowledge of genetic variants that influence blood pressure response to antihypertensive drugs may allow more individualized tailoring of antihypertensive drug therapy, and provide greater insight into the molecular mechanisms regulating blood pressure levels and causing hypertension.

AB - Sequencing of the human genome has elevated the potential for genetic information to aid in the prevention, diagnosis, and treatment of common chronic diseases. One beneficial application of genetic information is the identification of variants that influence response to pharmaceutical agents used to lower blood pressure and prevent target organ complications of hypertension. Knowledge of genetic variants that influence blood pressure response to antihypertensive drugs may allow more individualized tailoring of antihypertensive drug therapy, and provide greater insight into the molecular mechanisms regulating blood pressure levels and causing hypertension.

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JO - Current Hypertension Reports

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ER -

Use of gene markers to guide antihypertensive therapy

Abstract

ASJC Scopus subject areas

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