Update on intravenous leiomyomatosis: Report of five patients and literature review

Victoria Valdés Devesa, Christopher R. Conley, William M. Stone, Joseph M. Collins, Javier F. Magrina

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The objective of this study was to review management and results of surgical therapy of intravenous leiomyomatosis (IVL). A retrospective review of five patients treated at the Mayo Clinic between 2002 and 2012 and a literature review from 1970 to the present were performed. IVL is a rare condition, often overlooked, misdiagnosed or inadequately treated. Despite its benign histological features, invasion of large vessels and cardiac extension can occur and be fatal. Appropriate diagnosis and a radical surgical approach to IVL provide optimal outcomes. Incomplete resection and/or microscopic foci of IVL can lead to recurrence. Surgery should always aim for complete tumor excision and include hysterectomy and bilateral salpingoophorectomy. Radical parametrectomy and intravenous tumor resection may be necessary.

Original languageEnglish (US)
Pages (from-to)209-213
Number of pages5
JournalEuropean Journal of Obstetrics Gynecology and Reproductive Biology
Volume171
Issue number2
DOIs
StatePublished - Dec 2013

Fingerprint

Leiomyomatosis
Diagnostic Errors
Hysterectomy
Neoplasms
Recurrence

Keywords

  • Hysterectomy
  • Intravenous leiomyomatosis
  • Leiomyomatosis
  • Smooth muscle tumors

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Update on intravenous leiomyomatosis : Report of five patients and literature review. / Valdés Devesa, Victoria; Conley, Christopher R.; Stone, William M.; Collins, Joseph M.; Magrina, Javier F.

In: European Journal of Obstetrics Gynecology and Reproductive Biology, Vol. 171, No. 2, 12.2013, p. 209-213.

Research output: Contribution to journalArticle

Valdés Devesa, Victoria ; Conley, Christopher R. ; Stone, William M. ; Collins, Joseph M. ; Magrina, Javier F. / Update on intravenous leiomyomatosis : Report of five patients and literature review. In: European Journal of Obstetrics Gynecology and Reproductive Biology. 2013 ; Vol. 171, No. 2. pp. 209-213.
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