TY - JOUR
T1 - Update on intravenous leiomyomatosis
T2 - Report of five patients and literature review
AU - Valdés Devesa, Victoria
AU - Conley, Christopher R.
AU - Stone, William M.
AU - Collins, Joseph M.
AU - Magrina, Javier F.
PY - 2013/12
Y1 - 2013/12
N2 - The objective of this study was to review management and results of surgical therapy of intravenous leiomyomatosis (IVL). A retrospective review of five patients treated at the Mayo Clinic between 2002 and 2012 and a literature review from 1970 to the present were performed. IVL is a rare condition, often overlooked, misdiagnosed or inadequately treated. Despite its benign histological features, invasion of large vessels and cardiac extension can occur and be fatal. Appropriate diagnosis and a radical surgical approach to IVL provide optimal outcomes. Incomplete resection and/or microscopic foci of IVL can lead to recurrence. Surgery should always aim for complete tumor excision and include hysterectomy and bilateral salpingoophorectomy. Radical parametrectomy and intravenous tumor resection may be necessary.
AB - The objective of this study was to review management and results of surgical therapy of intravenous leiomyomatosis (IVL). A retrospective review of five patients treated at the Mayo Clinic between 2002 and 2012 and a literature review from 1970 to the present were performed. IVL is a rare condition, often overlooked, misdiagnosed or inadequately treated. Despite its benign histological features, invasion of large vessels and cardiac extension can occur and be fatal. Appropriate diagnosis and a radical surgical approach to IVL provide optimal outcomes. Incomplete resection and/or microscopic foci of IVL can lead to recurrence. Surgery should always aim for complete tumor excision and include hysterectomy and bilateral salpingoophorectomy. Radical parametrectomy and intravenous tumor resection may be necessary.
KW - Hysterectomy
KW - Intravenous leiomyomatosis
KW - Leiomyomatosis
KW - Smooth muscle tumors
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U2 - 10.1016/j.ejogrb.2013.09.031
DO - 10.1016/j.ejogrb.2013.09.031
M3 - Article
C2 - 24207051
AN - SCOPUS:84890431927
SN - 0301-2115
VL - 171
SP - 209
EP - 213
JO - European Journal of Obstetrics and Gynecology and Reproductive Biology
JF - European Journal of Obstetrics and Gynecology and Reproductive Biology
IS - 2
ER -