Uniaxially-aligned PVDF nanofibers as a sensor and transmitter for biotelemetry

Dennis Edmondson, Soumen Jana, David Wood, Chen Fang, Miqin Zhang

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Biotelemetry has become an important part of medical research for patient care by remotely monitoring continuing biological processes and physiological functions. However, current biotelemetry systems are complex requiring multiple electronic components to function: a battery, a sensor, and a transmitter, and a receiver. Another paramount concern of biotelemetry is the coupling of its in vivo portion to external supporting equipment. Here we report a novel biotelemetry device made primarily of a coiled bundle of uniaxially-aligned biocompatible polyvinylidene fluoride (PVDF) nanofibers of ∼200 nm in diameter and with piezoelectric properties that can serve concurrently as a power source, sensor, and transmitter. We tested this device on a cantilever beam that was periodically deflected at its free end. Without a power supply the coil of a nanofiber bundle is shown to generate and transmit an electrical signal wirelessly in response to the beam deflection which was received by an external receiver. The coil of a nanofiber bundle was encapsulated in a thin biocompatible polymer shell for device integrity and moisture isolation. Our results suggest that the device can potentially serve as a mechanical sensor and biotelemeter for various in vitro and in vivo biomedical applications.

Original languageEnglish (US)
Pages (from-to)7135-7139
Number of pages5
JournalAnalyst
Volume138
Issue number23
DOIs
StatePublished - Dec 7 2013
Externally publishedYes

Fingerprint

Biotelemetry
biotelemetry
Nanofibers
fluoride
Transmitters
sensor
Equipment and Supplies
Sensors
Electric Power Supplies
Cantilever beams
Biological Phenomena
deflection
biological processes
Polymers
Moisture
polymer
moisture
shell
Biomedical Research
Patient Care

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy
  • Electrochemistry

Cite this

Uniaxially-aligned PVDF nanofibers as a sensor and transmitter for biotelemetry. / Edmondson, Dennis; Jana, Soumen; Wood, David; Fang, Chen; Zhang, Miqin.

In: Analyst, Vol. 138, No. 23, 07.12.2013, p. 7135-7139.

Research output: Contribution to journalArticle

Edmondson, D, Jana, S, Wood, D, Fang, C & Zhang, M 2013, 'Uniaxially-aligned PVDF nanofibers as a sensor and transmitter for biotelemetry', Analyst, vol. 138, no. 23, pp. 7135-7139. https://doi.org/10.1039/c3an01346d
Edmondson, Dennis ; Jana, Soumen ; Wood, David ; Fang, Chen ; Zhang, Miqin. / Uniaxially-aligned PVDF nanofibers as a sensor and transmitter for biotelemetry. In: Analyst. 2013 ; Vol. 138, No. 23. pp. 7135-7139.
@article{2e496f3509c14720b049e4cddf67b30f,
title = "Uniaxially-aligned PVDF nanofibers as a sensor and transmitter for biotelemetry",
abstract = "Biotelemetry has become an important part of medical research for patient care by remotely monitoring continuing biological processes and physiological functions. However, current biotelemetry systems are complex requiring multiple electronic components to function: a battery, a sensor, and a transmitter, and a receiver. Another paramount concern of biotelemetry is the coupling of its in vivo portion to external supporting equipment. Here we report a novel biotelemetry device made primarily of a coiled bundle of uniaxially-aligned biocompatible polyvinylidene fluoride (PVDF) nanofibers of ∼200 nm in diameter and with piezoelectric properties that can serve concurrently as a power source, sensor, and transmitter. We tested this device on a cantilever beam that was periodically deflected at its free end. Without a power supply the coil of a nanofiber bundle is shown to generate and transmit an electrical signal wirelessly in response to the beam deflection which was received by an external receiver. The coil of a nanofiber bundle was encapsulated in a thin biocompatible polymer shell for device integrity and moisture isolation. Our results suggest that the device can potentially serve as a mechanical sensor and biotelemeter for various in vitro and in vivo biomedical applications.",
author = "Dennis Edmondson and Soumen Jana and David Wood and Chen Fang and Miqin Zhang",
year = "2013",
month = "12",
day = "7",
doi = "10.1039/c3an01346d",
language = "English (US)",
volume = "138",
pages = "7135--7139",
journal = "The Analyst",
issn = "0003-2654",
publisher = "Royal Society of Chemistry",
number = "23",

}

TY - JOUR

T1 - Uniaxially-aligned PVDF nanofibers as a sensor and transmitter for biotelemetry

AU - Edmondson, Dennis

AU - Jana, Soumen

AU - Wood, David

AU - Fang, Chen

AU - Zhang, Miqin

PY - 2013/12/7

Y1 - 2013/12/7

N2 - Biotelemetry has become an important part of medical research for patient care by remotely monitoring continuing biological processes and physiological functions. However, current biotelemetry systems are complex requiring multiple electronic components to function: a battery, a sensor, and a transmitter, and a receiver. Another paramount concern of biotelemetry is the coupling of its in vivo portion to external supporting equipment. Here we report a novel biotelemetry device made primarily of a coiled bundle of uniaxially-aligned biocompatible polyvinylidene fluoride (PVDF) nanofibers of ∼200 nm in diameter and with piezoelectric properties that can serve concurrently as a power source, sensor, and transmitter. We tested this device on a cantilever beam that was periodically deflected at its free end. Without a power supply the coil of a nanofiber bundle is shown to generate and transmit an electrical signal wirelessly in response to the beam deflection which was received by an external receiver. The coil of a nanofiber bundle was encapsulated in a thin biocompatible polymer shell for device integrity and moisture isolation. Our results suggest that the device can potentially serve as a mechanical sensor and biotelemeter for various in vitro and in vivo biomedical applications.

AB - Biotelemetry has become an important part of medical research for patient care by remotely monitoring continuing biological processes and physiological functions. However, current biotelemetry systems are complex requiring multiple electronic components to function: a battery, a sensor, and a transmitter, and a receiver. Another paramount concern of biotelemetry is the coupling of its in vivo portion to external supporting equipment. Here we report a novel biotelemetry device made primarily of a coiled bundle of uniaxially-aligned biocompatible polyvinylidene fluoride (PVDF) nanofibers of ∼200 nm in diameter and with piezoelectric properties that can serve concurrently as a power source, sensor, and transmitter. We tested this device on a cantilever beam that was periodically deflected at its free end. Without a power supply the coil of a nanofiber bundle is shown to generate and transmit an electrical signal wirelessly in response to the beam deflection which was received by an external receiver. The coil of a nanofiber bundle was encapsulated in a thin biocompatible polymer shell for device integrity and moisture isolation. Our results suggest that the device can potentially serve as a mechanical sensor and biotelemeter for various in vitro and in vivo biomedical applications.

UR - http://www.scopus.com/inward/record.url?scp=84886774126&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84886774126&partnerID=8YFLogxK

U2 - 10.1039/c3an01346d

DO - 10.1039/c3an01346d

M3 - Article

C2 - 24147273

AN - SCOPUS:84886774126

VL - 138

SP - 7135

EP - 7139

JO - The Analyst

JF - The Analyst

SN - 0003-2654

IS - 23

ER -