Ultrasound-guided hydrodissection decreases gliding resistance of the median nerve within the carpal tunnel

Stefanie Evers, Andrew R. Thoreson, Jay Smith, Chunfeng D Zhao, Jennifer R. Geske, Peter C Amadio

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Introduction: The aim of this study was to assess alterations in median nerve (MN) biomechanics within the carpal tunnel resulting from ultrasound-guided hydrodissection in a cadaveric model. Methods: Twelve fresh frozen human cadaver hands were used. MN gliding resistance was measured at baseline and posthydrodissection, by pulling the nerve proximally and then returning it to the origin. Six specimens were treated with hydrodissection, and 6 were used as controls. Results: In the hydrodissection group there was a significant reduction in mean peak gliding resistance of 92.9 ± 34.8 mN between baseline and immediately posthydrodissection (21.4% ± 10.5%; P = 0.001). No significant reduction between baseline and the second cycle occurred in the control group: 9.6 ± 29.8 mN (0.4% ± 5.3%; P = 0.467). Conclusions: Hydrodissection can decrease the gliding resistance of the MN within the carpal tunnel, at least in wrists unaffected by carpal tunnel syndrome. A clinical trial of hydrodissection seems justified.

Original languageEnglish (US)
JournalMuscle and Nerve
DOIs
StateAccepted/In press - 2017

Fingerprint

Median Nerve
Wrist
Carpal Tunnel Syndrome
Cadaver
Biomechanical Phenomena
Hand
Clinical Trials
Control Groups

Keywords

  • Carpal tunnel
  • Gliding resistance
  • Hydrodissection
  • Injection
  • Nerve
  • Ultrasound

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)

Cite this

Ultrasound-guided hydrodissection decreases gliding resistance of the median nerve within the carpal tunnel. / Evers, Stefanie; Thoreson, Andrew R.; Smith, Jay; Zhao, Chunfeng D; Geske, Jennifer R.; Amadio, Peter C.

In: Muscle and Nerve, 2017.

Research output: Contribution to journalArticle

@article{f644c045f6e3476a84d0e73bb6f75781,
title = "Ultrasound-guided hydrodissection decreases gliding resistance of the median nerve within the carpal tunnel",
abstract = "Introduction: The aim of this study was to assess alterations in median nerve (MN) biomechanics within the carpal tunnel resulting from ultrasound-guided hydrodissection in a cadaveric model. Methods: Twelve fresh frozen human cadaver hands were used. MN gliding resistance was measured at baseline and posthydrodissection, by pulling the nerve proximally and then returning it to the origin. Six specimens were treated with hydrodissection, and 6 were used as controls. Results: In the hydrodissection group there was a significant reduction in mean peak gliding resistance of 92.9 ± 34.8 mN between baseline and immediately posthydrodissection (21.4{\%} ± 10.5{\%}; P = 0.001). No significant reduction between baseline and the second cycle occurred in the control group: 9.6 ± 29.8 mN (0.4{\%} ± 5.3{\%}; P = 0.467). Conclusions: Hydrodissection can decrease the gliding resistance of the MN within the carpal tunnel, at least in wrists unaffected by carpal tunnel syndrome. A clinical trial of hydrodissection seems justified.",
keywords = "Carpal tunnel, Gliding resistance, Hydrodissection, Injection, Nerve, Ultrasound",
author = "Stefanie Evers and Thoreson, {Andrew R.} and Jay Smith and Zhao, {Chunfeng D} and Geske, {Jennifer R.} and Amadio, {Peter C}",
year = "2017",
doi = "10.1002/mus.25723",
language = "English (US)",
journal = "Muscle and Nerve",
issn = "0148-639X",
publisher = "John Wiley and Sons Inc.",

}

TY - JOUR

T1 - Ultrasound-guided hydrodissection decreases gliding resistance of the median nerve within the carpal tunnel

AU - Evers, Stefanie

AU - Thoreson, Andrew R.

AU - Smith, Jay

AU - Zhao, Chunfeng D

AU - Geske, Jennifer R.

AU - Amadio, Peter C

PY - 2017

Y1 - 2017

N2 - Introduction: The aim of this study was to assess alterations in median nerve (MN) biomechanics within the carpal tunnel resulting from ultrasound-guided hydrodissection in a cadaveric model. Methods: Twelve fresh frozen human cadaver hands were used. MN gliding resistance was measured at baseline and posthydrodissection, by pulling the nerve proximally and then returning it to the origin. Six specimens were treated with hydrodissection, and 6 were used as controls. Results: In the hydrodissection group there was a significant reduction in mean peak gliding resistance of 92.9 ± 34.8 mN between baseline and immediately posthydrodissection (21.4% ± 10.5%; P = 0.001). No significant reduction between baseline and the second cycle occurred in the control group: 9.6 ± 29.8 mN (0.4% ± 5.3%; P = 0.467). Conclusions: Hydrodissection can decrease the gliding resistance of the MN within the carpal tunnel, at least in wrists unaffected by carpal tunnel syndrome. A clinical trial of hydrodissection seems justified.

AB - Introduction: The aim of this study was to assess alterations in median nerve (MN) biomechanics within the carpal tunnel resulting from ultrasound-guided hydrodissection in a cadaveric model. Methods: Twelve fresh frozen human cadaver hands were used. MN gliding resistance was measured at baseline and posthydrodissection, by pulling the nerve proximally and then returning it to the origin. Six specimens were treated with hydrodissection, and 6 were used as controls. Results: In the hydrodissection group there was a significant reduction in mean peak gliding resistance of 92.9 ± 34.8 mN between baseline and immediately posthydrodissection (21.4% ± 10.5%; P = 0.001). No significant reduction between baseline and the second cycle occurred in the control group: 9.6 ± 29.8 mN (0.4% ± 5.3%; P = 0.467). Conclusions: Hydrodissection can decrease the gliding resistance of the MN within the carpal tunnel, at least in wrists unaffected by carpal tunnel syndrome. A clinical trial of hydrodissection seems justified.

KW - Carpal tunnel

KW - Gliding resistance

KW - Hydrodissection

KW - Injection

KW - Nerve

KW - Ultrasound

UR - http://www.scopus.com/inward/record.url?scp=85021817648&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85021817648&partnerID=8YFLogxK

U2 - 10.1002/mus.25723

DO - 10.1002/mus.25723

M3 - Article

JO - Muscle and Nerve

JF - Muscle and Nerve

SN - 0148-639X

ER -