TY - JOUR
T1 - Two-stage exchange arthroplasty using a functional antibiotic-loaded spacer in the treatment of the infected knee replacement
T2 - the Vancouver experience.
AU - Masri, B. A.
AU - Kendall, R. W.
AU - Duncan, C. P.
AU - Beauchamp, C. P.
AU - McGraw, R. W.
AU - Bora, B.
PY - 1994/7
Y1 - 1994/7
N2 - Two-stage exchange arthroplasty is currently the method of choice in the treatment of the infected knee replacement. The prosthesis of antibiotic-loaded acrylic cement (PROSTALAC) is a temporary, antibiotic-loaded functional prosthesis that is used as an interim spacer in two-stage exchange arthroplasty. In this prospective series, we report on the early results of the use of the PROSTALAC knee spacer in two-stage exchange arthroplasty of infected knees. A total of 24 knees were treated with this prosthesis, and were reviewed at a mean follow-up time of 2.2 years. Infection was controlled in all but 2 knees, for an infection cure rate of 91.7%. The patients' function was improved between stages, and motion was maintained in the majority of cases. The significant complications with the PROSTALAC implant in place were tibio-femoral instability, which was corrected with a design modification, and patellar instability, which continues to be a problem. These complications were transient and were not of any significance after the second stage.
AB - Two-stage exchange arthroplasty is currently the method of choice in the treatment of the infected knee replacement. The prosthesis of antibiotic-loaded acrylic cement (PROSTALAC) is a temporary, antibiotic-loaded functional prosthesis that is used as an interim spacer in two-stage exchange arthroplasty. In this prospective series, we report on the early results of the use of the PROSTALAC knee spacer in two-stage exchange arthroplasty of infected knees. A total of 24 knees were treated with this prosthesis, and were reviewed at a mean follow-up time of 2.2 years. Infection was controlled in all but 2 knees, for an infection cure rate of 91.7%. The patients' function was improved between stages, and motion was maintained in the majority of cases. The significant complications with the PROSTALAC implant in place were tibio-femoral instability, which was corrected with a design modification, and patellar instability, which continues to be a problem. These complications were transient and were not of any significance after the second stage.
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M3 - Article
C2 - 10155154
AN - SCOPUS:0028476509
SN - 1045-4527
VL - 5
SP - 122
EP - 136
JO - Seminars in arthroplasty
JF - Seminars in arthroplasty
IS - 3
ER -