Abstract
OBJECTIVE. The tumefactive variant of cerebral amyloid angiopathy (CAA) is rare. In this article we describe imaging findings associated with this entity and evaluate the role of susceptibility MRI sequences in its diagnosis. CONCLUSION. Our findings suggest that in elderly patients, susceptibility sequences should be part of prebiopsy MRI for tumefactive lesions. Identification of characteristic diffuse microhemorrhages should prompt inclusion of CAA in the differential diagnosis, targeted biopsy of the cortex and leptomeninges, and pathologic staining for CAA.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 50-56 |
| Number of pages | 7 |
| Journal | American Journal of Roentgenology |
| Volume | 200 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2013 |
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Keywords
- Cerebral amyloid angiopathy
- CNS
- Microhemorrhage
- Neoplasm
- Superficial hemosiderosis
- Susceptibility MRI sequences
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Tumefactive cerebral amyloid angiopathy mimicking CNS neoplasm. / Kotsenas, Amy L.; Morris, Jonathan M.; Wald, John T.; Parisi, Joseph E; Campeau, Norbert G.
In: American Journal of Roentgenology, Vol. 200, No. 1, 01.2013, p. 50-56.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Tumefactive cerebral amyloid angiopathy mimicking CNS neoplasm
AU - Kotsenas, Amy L.
AU - Morris, Jonathan M.
AU - Wald, John T.
AU - Parisi, Joseph E
AU - Campeau, Norbert G
PY - 2013/1
Y1 - 2013/1
N2 - OBJECTIVE. The tumefactive variant of cerebral amyloid angiopathy (CAA) is rare. In this article we describe imaging findings associated with this entity and evaluate the role of susceptibility MRI sequences in its diagnosis. CONCLUSION. Our findings suggest that in elderly patients, susceptibility sequences should be part of prebiopsy MRI for tumefactive lesions. Identification of characteristic diffuse microhemorrhages should prompt inclusion of CAA in the differential diagnosis, targeted biopsy of the cortex and leptomeninges, and pathologic staining for CAA.
AB - OBJECTIVE. The tumefactive variant of cerebral amyloid angiopathy (CAA) is rare. In this article we describe imaging findings associated with this entity and evaluate the role of susceptibility MRI sequences in its diagnosis. CONCLUSION. Our findings suggest that in elderly patients, susceptibility sequences should be part of prebiopsy MRI for tumefactive lesions. Identification of characteristic diffuse microhemorrhages should prompt inclusion of CAA in the differential diagnosis, targeted biopsy of the cortex and leptomeninges, and pathologic staining for CAA.
KW - Cerebral amyloid angiopathy
KW - CNS
KW - Microhemorrhage
KW - Neoplasm
KW - Superficial hemosiderosis
KW - Susceptibility MRI sequences
UR - http://www.scopus.com/inward/record.url?scp=84871893148&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84871893148&partnerID=8YFLogxK
U2 - 10.2214/AJR.12.8500
DO - 10.2214/AJR.12.8500
M3 - Article
C2 - 23255741
AN - SCOPUS:84871893148
VL - 200
SP - 50
EP - 56
JO - American Journal of Roentgenology
JF - American Journal of Roentgenology
SN - 0361-803X
IS - 1
ER -