Trends in right and left-sided colon cancer

Robert W. Beart, L. Joseph Melton, Morito Maruta, Malcolm B. Dockerty, Harry B. Frydenberg, W. Michael O'Fallon

Research output: Contribution to journalArticle

149 Citations (Scopus)

Abstract

The increasing ratio of proximal to distal colorectal carcinomas was confirmed in this population-based study of 668 new cases diagnosed among Rochester, Minnesota residents between 1940 and 1979. The change was due to a rise in the incidence of proximal lesions (from 15.1 per 100,000 person-years in 1940-59 to 17.3 per 100,000 in 1960-79) and a simultaneous fall in the incidence of distal lesions (from 35.5 to 28.2 per 100,000 person-years). Changes in definitions or referral patterns played no role in these observations, although improved diagnostic capabilities may have had an impact on the incidence of proximal lesions. These discrepant changes in incidence strongly suggest that proximal and distal colonic cancers are different diseases or have a different pathogenesis. The changing incidence rates were not associated with consistent differences in clinical characteristics at the time of initial diagnosis.

Original languageEnglish (US)
Pages (from-to)393-398
Number of pages6
JournalDiseases of the Colon & Rectum
Volume26
Issue number6
DOIs
StatePublished - Jun 1983

Fingerprint

Colonic Neoplasms
Incidence
Colorectal Neoplasms
Referral and Consultation
Population

Keywords

  • Carcinoma, colorectal
  • Epidemiology
  • Population-based study

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Beart, R. W., Melton, L. J., Maruta, M., Dockerty, M. B., Frydenberg, H. B., & O'Fallon, W. M. (1983). Trends in right and left-sided colon cancer. Diseases of the Colon & Rectum, 26(6), 393-398. https://doi.org/10.1007/BF02553382

Trends in right and left-sided colon cancer. / Beart, Robert W.; Melton, L. Joseph; Maruta, Morito; Dockerty, Malcolm B.; Frydenberg, Harry B.; O'Fallon, W. Michael.

In: Diseases of the Colon & Rectum, Vol. 26, No. 6, 06.1983, p. 393-398.

Research output: Contribution to journalArticle

Beart, RW, Melton, LJ, Maruta, M, Dockerty, MB, Frydenberg, HB & O'Fallon, WM 1983, 'Trends in right and left-sided colon cancer', Diseases of the Colon & Rectum, vol. 26, no. 6, pp. 393-398. https://doi.org/10.1007/BF02553382
Beart RW, Melton LJ, Maruta M, Dockerty MB, Frydenberg HB, O'Fallon WM. Trends in right and left-sided colon cancer. Diseases of the Colon & Rectum. 1983 Jun;26(6):393-398. https://doi.org/10.1007/BF02553382
Beart, Robert W. ; Melton, L. Joseph ; Maruta, Morito ; Dockerty, Malcolm B. ; Frydenberg, Harry B. ; O'Fallon, W. Michael. / Trends in right and left-sided colon cancer. In: Diseases of the Colon & Rectum. 1983 ; Vol. 26, No. 6. pp. 393-398.
@article{a311d339a5f743c8ba44590af333daef,
title = "Trends in right and left-sided colon cancer",
abstract = "The increasing ratio of proximal to distal colorectal carcinomas was confirmed in this population-based study of 668 new cases diagnosed among Rochester, Minnesota residents between 1940 and 1979. The change was due to a rise in the incidence of proximal lesions (from 15.1 per 100,000 person-years in 1940-59 to 17.3 per 100,000 in 1960-79) and a simultaneous fall in the incidence of distal lesions (from 35.5 to 28.2 per 100,000 person-years). Changes in definitions or referral patterns played no role in these observations, although improved diagnostic capabilities may have had an impact on the incidence of proximal lesions. These discrepant changes in incidence strongly suggest that proximal and distal colonic cancers are different diseases or have a different pathogenesis. The changing incidence rates were not associated with consistent differences in clinical characteristics at the time of initial diagnosis.",
keywords = "Carcinoma, colorectal, Epidemiology, Population-based study",
author = "Beart, {Robert W.} and Melton, {L. Joseph} and Morito Maruta and Dockerty, {Malcolm B.} and Frydenberg, {Harry B.} and O'Fallon, {W. Michael}",
year = "1983",
month = "6",
doi = "10.1007/BF02553382",
language = "English (US)",
volume = "26",
pages = "393--398",
journal = "Diseases of the Colon and Rectum",
issn = "0012-3706",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Trends in right and left-sided colon cancer

AU - Beart, Robert W.

AU - Melton, L. Joseph

AU - Maruta, Morito

AU - Dockerty, Malcolm B.

AU - Frydenberg, Harry B.

AU - O'Fallon, W. Michael

PY - 1983/6

Y1 - 1983/6

N2 - The increasing ratio of proximal to distal colorectal carcinomas was confirmed in this population-based study of 668 new cases diagnosed among Rochester, Minnesota residents between 1940 and 1979. The change was due to a rise in the incidence of proximal lesions (from 15.1 per 100,000 person-years in 1940-59 to 17.3 per 100,000 in 1960-79) and a simultaneous fall in the incidence of distal lesions (from 35.5 to 28.2 per 100,000 person-years). Changes in definitions or referral patterns played no role in these observations, although improved diagnostic capabilities may have had an impact on the incidence of proximal lesions. These discrepant changes in incidence strongly suggest that proximal and distal colonic cancers are different diseases or have a different pathogenesis. The changing incidence rates were not associated with consistent differences in clinical characteristics at the time of initial diagnosis.

AB - The increasing ratio of proximal to distal colorectal carcinomas was confirmed in this population-based study of 668 new cases diagnosed among Rochester, Minnesota residents between 1940 and 1979. The change was due to a rise in the incidence of proximal lesions (from 15.1 per 100,000 person-years in 1940-59 to 17.3 per 100,000 in 1960-79) and a simultaneous fall in the incidence of distal lesions (from 35.5 to 28.2 per 100,000 person-years). Changes in definitions or referral patterns played no role in these observations, although improved diagnostic capabilities may have had an impact on the incidence of proximal lesions. These discrepant changes in incidence strongly suggest that proximal and distal colonic cancers are different diseases or have a different pathogenesis. The changing incidence rates were not associated with consistent differences in clinical characteristics at the time of initial diagnosis.

KW - Carcinoma, colorectal

KW - Epidemiology

KW - Population-based study

UR - http://www.scopus.com/inward/record.url?scp=0020628011&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020628011&partnerID=8YFLogxK

U2 - 10.1007/BF02553382

DO - 10.1007/BF02553382

M3 - Article

C2 - 6851801

AN - SCOPUS:0020628011

VL - 26

SP - 393

EP - 398

JO - Diseases of the Colon and Rectum

JF - Diseases of the Colon and Rectum

SN - 0012-3706

IS - 6

ER -