Translation of pharmacogenetics into clinically relevant testing modalities

L. M. Baudhuin; L. J. Langman; D. J. O'Kane

doi:10.1038/sj.clpt.6100350

Translation of pharmacogenetics into clinically relevant testing modalities

L. M. Baudhuin, L. J. Langman, D. J. O'Kane

Laboratory Medicine and Pathology

Research output: Contribution to journal › Short survey › peer-review

14 Scopus citations

Abstract

Pharmacogenetics (PGx) relies on the genetic makeup of an individual to predict drug response and efficacy, as well as potential adverse drug events. Significant advances in PGx research have been made since inherited differences in response to such drugs as isoniazid and succinylcholine were explored in the 1950s,^1,2 and the clinical utility and application of PGx are especially apparent in some subspecialty areas of chemotherapeutic, psychotropic drug, and anticoagulant therapies.

Original language	English (US)
Pages (from-to)	373-376
Number of pages	4
Journal	Clinical pharmacology and therapeutics
Volume	82
Issue number	4
DOIs	https://doi.org/10.1038/sj.clpt.6100350
State	Published - Oct 2007

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)

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AU - Langman, L. J.

AU - O'Kane, D. J.

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AB - Pharmacogenetics (PGx) relies on the genetic makeup of an individual to predict drug response and efficacy, as well as potential adverse drug events. Significant advances in PGx research have been made since inherited differences in response to such drugs as isoniazid and succinylcholine were explored in the 1950s,1,2 and the clinical utility and application of PGx are especially apparent in some subspecialty areas of chemotherapeutic, psychotropic drug, and anticoagulant therapies.

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Translation of pharmacogenetics into clinically relevant testing modalities

Abstract

ASJC Scopus subject areas

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