Tissue characterization using simultaneous estimation of backscatter coefficient and elastic shear modulus

Julien Rouyer, Gabriela Torres, Matthew W Urban, Roberto Lavarello

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Tissue characterization using quantitative ultrasound (QUS) parameters has received significant attention in recent years due to its potential to improve the detection and diagnosis of diseased states. However, the vast majority of studies in QUS tissue typing have used parameters derived from either longitudinal or shear waves in isolation, thereby discarding potentially useful complementary information these parameters may carry. In this study, the simultaneous estimation of backscatter coefficients (derived from longitudinal waves) and shear modulus (derived from shear waves) was implemented on data from a clinical scanner. Both parameters were estimated from five ex vivo porcine kidney samples and used to calculate the anisotropy ratio in the parameters when analyzing the middle and pole regions of the kidneys. For all samples, the estimated parameters were higher in the pole regions than in the middle region, with anisotropy ratios of 1.42±0.11 and 3.07±0.70 for the shear modulus and the backscatter coefficient, respectively. Therefore, these results demonstrate that QUS parameters derived from both longitudinal and shear waves can be estimated simultaneously and may be used in conjunction to track changes in tissue structure and composition.

Original languageEnglish (US)
Title of host publication2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages2881-2884
Number of pages4
Volume2016-October
ISBN (Electronic)9781457702204
DOIs
StatePublished - Oct 13 2016
Event38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 - Orlando, United States
Duration: Aug 16 2016Aug 20 2016

Other

Other38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
CountryUnited States
CityOrlando
Period8/16/168/20/16

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ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Rouyer, J., Torres, G., Urban, M. W., & Lavarello, R. (2016). Tissue characterization using simultaneous estimation of backscatter coefficient and elastic shear modulus. In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 (Vol. 2016-October, pp. 2881-2884). [7591331] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2016.7591331