Time reversal principles for wave optimization in multiple driver magnetic resonance elastography

Yogesh K. Mariappan, Armando Manduca, Richard Lorne Ehman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Magnetic Resonance Elastography (MRE) quantitatively maps the stiffness of tissues by imaging propagating shear waves induced by mechanical transducers. It has been shown that by using multiple drivers, certain limitations of conventional single driver MRE can be reduced, and that by suitably adjusting the waveforms applied to these drivers, any arbitrary region of interest can be optimally illuminated (wave optimization). Typically these adjustments were derived from wave response data collected for each transducer individually, which increases the total scan time. To address this issue, we investigated the use of time reversal principles to calculate the appropriate waveforms and their potential advantages in MRE exams. A phased array acoustic driver system with four independent 'daughter' transducers was used. An additional shear 'parent' transducer was used to create shear waves at the ROI, and wave propagation data was collected with MRE both in continuous and transient wave mode. From these single source wave data, the appropriate phase and time offset relationships between the daughter transducers were derived. Separate experiments were then carried out driving the daughter transducers with these calculated motions, and wave optimization was achieved in both continuous and transient wave MRE. We conclude that time reversal principles could be used for wave optimization with multiple drivers and could potentially reduce the total scan time.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6511
EditionPART 1
DOIs
StatePublished - 2007
EventMedical Imaging 2007: Physiology, Function, and Structure from Medical Images - San Diego, CA, United States
Duration: Feb 18 2007Feb 20 2007

Other

OtherMedical Imaging 2007: Physiology, Function, and Structure from Medical Images
CountryUnited States
CitySan Diego, CA
Period2/18/072/20/07

Fingerprint

Magnetic resonance
Transducers
Shear waves
Wave propagation
Acoustics
Stiffness
Tissue
Imaging techniques
Experiments

Keywords

  • Elasticity
  • Elastography
  • Magnetic resonance elastography
  • Shear modulus
  • Time reversal

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Mariappan, Y. K., Manduca, A., & Ehman, R. L. (2007). Time reversal principles for wave optimization in multiple driver magnetic resonance elastography. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (PART 1 ed., Vol. 6511). [651119] https://doi.org/10.1117/12.710717

Time reversal principles for wave optimization in multiple driver magnetic resonance elastography. / Mariappan, Yogesh K.; Manduca, Armando; Ehman, Richard Lorne.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6511 PART 1. ed. 2007. 651119.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mariappan, YK, Manduca, A & Ehman, RL 2007, Time reversal principles for wave optimization in multiple driver magnetic resonance elastography. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. PART 1 edn, vol. 6511, 651119, Medical Imaging 2007: Physiology, Function, and Structure from Medical Images, San Diego, CA, United States, 2/18/07. https://doi.org/10.1117/12.710717
Mariappan YK, Manduca A, Ehman RL. Time reversal principles for wave optimization in multiple driver magnetic resonance elastography. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. PART 1 ed. Vol. 6511. 2007. 651119 https://doi.org/10.1117/12.710717
Mariappan, Yogesh K. ; Manduca, Armando ; Ehman, Richard Lorne. / Time reversal principles for wave optimization in multiple driver magnetic resonance elastography. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6511 PART 1. ed. 2007.
@inproceedings{6c01334e17d14b6496feaa2a313e0353,
title = "Time reversal principles for wave optimization in multiple driver magnetic resonance elastography",
abstract = "Magnetic Resonance Elastography (MRE) quantitatively maps the stiffness of tissues by imaging propagating shear waves induced by mechanical transducers. It has been shown that by using multiple drivers, certain limitations of conventional single driver MRE can be reduced, and that by suitably adjusting the waveforms applied to these drivers, any arbitrary region of interest can be optimally illuminated (wave optimization). Typically these adjustments were derived from wave response data collected for each transducer individually, which increases the total scan time. To address this issue, we investigated the use of time reversal principles to calculate the appropriate waveforms and their potential advantages in MRE exams. A phased array acoustic driver system with four independent 'daughter' transducers was used. An additional shear 'parent' transducer was used to create shear waves at the ROI, and wave propagation data was collected with MRE both in continuous and transient wave mode. From these single source wave data, the appropriate phase and time offset relationships between the daughter transducers were derived. Separate experiments were then carried out driving the daughter transducers with these calculated motions, and wave optimization was achieved in both continuous and transient wave MRE. We conclude that time reversal principles could be used for wave optimization with multiple drivers and could potentially reduce the total scan time.",
keywords = "Elasticity, Elastography, Magnetic resonance elastography, Shear modulus, Time reversal",
author = "Mariappan, {Yogesh K.} and Armando Manduca and Ehman, {Richard Lorne}",
year = "2007",
doi = "10.1117/12.710717",
language = "English (US)",
isbn = "0819466298",
volume = "6511",
booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
edition = "PART 1",

}

TY - GEN

T1 - Time reversal principles for wave optimization in multiple driver magnetic resonance elastography

AU - Mariappan, Yogesh K.

AU - Manduca, Armando

AU - Ehman, Richard Lorne

PY - 2007

Y1 - 2007

N2 - Magnetic Resonance Elastography (MRE) quantitatively maps the stiffness of tissues by imaging propagating shear waves induced by mechanical transducers. It has been shown that by using multiple drivers, certain limitations of conventional single driver MRE can be reduced, and that by suitably adjusting the waveforms applied to these drivers, any arbitrary region of interest can be optimally illuminated (wave optimization). Typically these adjustments were derived from wave response data collected for each transducer individually, which increases the total scan time. To address this issue, we investigated the use of time reversal principles to calculate the appropriate waveforms and their potential advantages in MRE exams. A phased array acoustic driver system with four independent 'daughter' transducers was used. An additional shear 'parent' transducer was used to create shear waves at the ROI, and wave propagation data was collected with MRE both in continuous and transient wave mode. From these single source wave data, the appropriate phase and time offset relationships between the daughter transducers were derived. Separate experiments were then carried out driving the daughter transducers with these calculated motions, and wave optimization was achieved in both continuous and transient wave MRE. We conclude that time reversal principles could be used for wave optimization with multiple drivers and could potentially reduce the total scan time.

AB - Magnetic Resonance Elastography (MRE) quantitatively maps the stiffness of tissues by imaging propagating shear waves induced by mechanical transducers. It has been shown that by using multiple drivers, certain limitations of conventional single driver MRE can be reduced, and that by suitably adjusting the waveforms applied to these drivers, any arbitrary region of interest can be optimally illuminated (wave optimization). Typically these adjustments were derived from wave response data collected for each transducer individually, which increases the total scan time. To address this issue, we investigated the use of time reversal principles to calculate the appropriate waveforms and their potential advantages in MRE exams. A phased array acoustic driver system with four independent 'daughter' transducers was used. An additional shear 'parent' transducer was used to create shear waves at the ROI, and wave propagation data was collected with MRE both in continuous and transient wave mode. From these single source wave data, the appropriate phase and time offset relationships between the daughter transducers were derived. Separate experiments were then carried out driving the daughter transducers with these calculated motions, and wave optimization was achieved in both continuous and transient wave MRE. We conclude that time reversal principles could be used for wave optimization with multiple drivers and could potentially reduce the total scan time.

KW - Elasticity

KW - Elastography

KW - Magnetic resonance elastography

KW - Shear modulus

KW - Time reversal

UR - http://www.scopus.com/inward/record.url?scp=35148816661&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35148816661&partnerID=8YFLogxK

U2 - 10.1117/12.710717

DO - 10.1117/12.710717

M3 - Conference contribution

AN - SCOPUS:35148816661

SN - 0819466298

SN - 9780819466297

VL - 6511

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

ER -