Three-dimensional volumetric computed tomographic scoring as an objective outcome measure for chronic rhinosinusitis: Clinical correlations and comparison to Lund-Mackay scoring

John F. Pallanch, Lifeng Yu, David Delone, Rich Robb, David R. Holmes, Jon Camp, Phil Edwards, Cynthia H. Mccollough, Jens Ponikau, Amy C. Dearking, John Lane, Andrew Primak, Aaron Shinkle, John Hagan, Evangelo Frigas, Joseph J. Ocel, Nicole Tombers, Rizwan Siwani, Nicholas M. Orme, Kurtis B. ReedNivedita Jerath, Robinder Dhillon, Hirohito Kita

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Background: We aimed to test the hypothesis that three-dimensional (3D) volume-based scoring of computed tomography (CT) images of the paranasal sinuses was superior to Lund-Mackay CT scoring of disease severity in chronic rhinosinusitis (CRS). We determined correlation between changes in CT scores (using each scoring system) with changes in other measures of disease severity (symptoms, endoscopic scoring, and quality of life) in patients with CRS treated with triamcinolone. Methods: The study group comprised 48 adult subjects with CRS. Baseline symptoms and quality of life were assessed. Endoscopy and CT scans were performed. Patients received a single systemic dose of intramuscular triamcinolone and were reevaluated 1 month later. Strengths of the correlations between changes in CT scores and changes in CRS signs and symptoms and quality of life were determined. Results: We observed some variability in degree of improvement for the different symptom, endoscopic, and quality-of-life parameters after treatment. Improvement of parameters was significantly correlated with improvement in CT disease score using both CT scoring methods. However, volumetric CT scoring had greater correlation with these parameters than Lund-Mackay scoring. Conclusion: Volumetric scoring exhibited higher degree of correlation than Lund-Mackay scoring when comparing improvement in CT score with improvement in score for symptoms, endoscopic exam, and quality of life in this group of patients who received beneficial medical treatment for CRS.

Original languageEnglish (US)
Pages (from-to)963-972
Number of pages10
JournalInternational Forum of Allergy and Rhinology
Volume3
Issue number12
DOIs
StatePublished - Dec 2013

Keywords

  • Computed tomography
  • Computer-assisted image analysis
  • Endoscopy
  • Lund-Mackay
  • Quality of life

ASJC Scopus subject areas

  • Immunology and Allergy
  • Otorhinolaryngology

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    Pallanch, J. F., Yu, L., Delone, D., Robb, R., Holmes, D. R., Camp, J., Edwards, P., Mccollough, C. H., Ponikau, J., Dearking, A. C., Lane, J., Primak, A., Shinkle, A., Hagan, J., Frigas, E., Ocel, J. J., Tombers, N., Siwani, R., Orme, N. M., ... Kita, H. (2013). Three-dimensional volumetric computed tomographic scoring as an objective outcome measure for chronic rhinosinusitis: Clinical correlations and comparison to Lund-Mackay scoring. International Forum of Allergy and Rhinology, 3(12), 963-972. https://doi.org/10.1002/alr.21219