Therapeutic radiation and hyperparathyroidism. A case-control study in Rochester, Minn

C. M. Beard, H. Heath, W. M. O'Fallon, J. A. Anderson, J. D. Earle, L. J. Melton

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

A case-control study was conducted among residents of Rochester, Minn, to assess the influence of prior therapeutic radiation on the risk of primary hyperparathyrodism. Fifty-one cases of surgically proven primary hyperparathyroidism diagnosed from 1975 through 1983 were each matched by age and gender to two control subjects, with radiation exposure documented through preexisting medical records. The overall odds ratio for any prior therapeutic radiation therapy was 1.9 (95% confidence interval, 0.9 to 4.4) and it was 2.3 (95% confidence interval, 0.9 to 5.7) when limited to those with prior head and neck radiation. Among women, the figures were 2.9 (95% confidence interval, 1.1 to 7.5) for any prior therapeutic radiation and 3.4 (95% confidence interval, 1.2 to 10.2) for head and neck exposure. This study confirms the association between primary hyperparathyroidism and prior therapeutic radiation exposure, at least for women in this population.

Original languageEnglish (US)
Pages (from-to)1887-1890
Number of pages4
JournalArchives of Internal Medicine
Volume149
Issue number8
StatePublished - 1989

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Hyperparathyroidism
Case-Control Studies
Confidence Intervals
Radiation
Primary Hyperparathyroidism
Neck
Head
Therapeutics
Medical Records
Radiotherapy
Odds Ratio
Population
Radiation Exposure

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Beard, C. M., Heath, H., O'Fallon, W. M., Anderson, J. A., Earle, J. D., & Melton, L. J. (1989). Therapeutic radiation and hyperparathyroidism. A case-control study in Rochester, Minn. Archives of Internal Medicine, 149(8), 1887-1890.

Therapeutic radiation and hyperparathyroidism. A case-control study in Rochester, Minn. / Beard, C. M.; Heath, H.; O'Fallon, W. M.; Anderson, J. A.; Earle, J. D.; Melton, L. J.

In: Archives of Internal Medicine, Vol. 149, No. 8, 1989, p. 1887-1890.

Research output: Contribution to journalArticle

Beard, CM, Heath, H, O'Fallon, WM, Anderson, JA, Earle, JD & Melton, LJ 1989, 'Therapeutic radiation and hyperparathyroidism. A case-control study in Rochester, Minn', Archives of Internal Medicine, vol. 149, no. 8, pp. 1887-1890.
Beard CM, Heath H, O'Fallon WM, Anderson JA, Earle JD, Melton LJ. Therapeutic radiation and hyperparathyroidism. A case-control study in Rochester, Minn. Archives of Internal Medicine. 1989;149(8):1887-1890.
Beard, C. M. ; Heath, H. ; O'Fallon, W. M. ; Anderson, J. A. ; Earle, J. D. ; Melton, L. J. / Therapeutic radiation and hyperparathyroidism. A case-control study in Rochester, Minn. In: Archives of Internal Medicine. 1989 ; Vol. 149, No. 8. pp. 1887-1890.
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