The venoarteriolar reflex in diabetic and other neuropathies

S. Moy, T. L. Opfer-Gehrking, C. J. Proper, Phillip Anson Low

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Limb dependency activates the venoarteriolar reflex (VAR), resulting in reflex vasoconstriction (RV). Since others have reported the VAR to fail in diabetic neuropathy, we examined the reliability of this test in detecting sympathetic failure in diabetic and other neuropathies. We studied 40 controls, 49 diabetic subjects, and 29 patients with other neuropathies. The mean RV was greater in controls than in diabetics or other neuropathies, but there were marked overlaps among groups. We conclude that the VAR, while impaired in the neuropathies, is of little value as a clinical test and is a poorer test of autonomic function than the quantitative axon reflex test or heart rate responses to deep breathing or the Valsalva maneuver.

Original languageEnglish (US)
Pages (from-to)1490-1492
Number of pages3
JournalNeurology
Volume39
Issue number11
StatePublished - 1989

Fingerprint

Diabetic Neuropathies
Reflex
Vasoconstriction
Valsalva Maneuver
Axons
Respiration
Extremities
Heart Rate

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Moy, S., Opfer-Gehrking, T. L., Proper, C. J., & Low, P. A. (1989). The venoarteriolar reflex in diabetic and other neuropathies. Neurology, 39(11), 1490-1492.

The venoarteriolar reflex in diabetic and other neuropathies. / Moy, S.; Opfer-Gehrking, T. L.; Proper, C. J.; Low, Phillip Anson.

In: Neurology, Vol. 39, No. 11, 1989, p. 1490-1492.

Research output: Contribution to journalArticle

Moy, S, Opfer-Gehrking, TL, Proper, CJ & Low, PA 1989, 'The venoarteriolar reflex in diabetic and other neuropathies', Neurology, vol. 39, no. 11, pp. 1490-1492.
Moy S, Opfer-Gehrking TL, Proper CJ, Low PA. The venoarteriolar reflex in diabetic and other neuropathies. Neurology. 1989;39(11):1490-1492.
Moy, S. ; Opfer-Gehrking, T. L. ; Proper, C. J. ; Low, Phillip Anson. / The venoarteriolar reflex in diabetic and other neuropathies. In: Neurology. 1989 ; Vol. 39, No. 11. pp. 1490-1492.
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