The treatable dementia of sjögren's syndrome

Richard J. Caselli, Bernd W. Scheithauer, Carolyn A. Bowles, Max R. Trenerry, Fredric B. Meyer, Jeffrey S. Smigielski, Moses Rodriguez

Research output: Contribution to journalArticle

71 Scopus citations


Progressive dementia developed during a 15‐month period in a 56‐year‐old woman with serologically and clinically documented primary Sjögren's syndrome. Findings from magnetic resonance imaging and angiography were normal, but a brain biopsy disclosed perivascular lymphocytic inflammation in leptomeningeal and parenchymal vessels. Treatment with high‐dose corticosteroids produced rapid and nearly complete resolution of the dementia.

Original languageEnglish (US)
Pages (from-to)98-101
Number of pages4
JournalAnnals of neurology
Issue number1
StatePublished - Jul 1991


ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Caselli, R. J., Scheithauer, B. W., Bowles, C. A., Trenerry, M. R., Meyer, F. B., Smigielski, J. S., & Rodriguez, M. (1991). The treatable dementia of sjögren's syndrome. Annals of neurology, 30(1), 98-101.