The sympathetic nervous system in alcoholic neuropathy: a clinical and pathological study

Phillip Anson Low, J. C. Walsh, C. Y. Huang, J. G. McLeod

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Tests of autonomic function were performed on 12 subjects with alcoholic neuropathy. Abnormal sweat patterns occurred in 8/8 (100%) and an abnormal Valsalva ratio in 2/9 (22%). Postural hypotension and denervation hypersensitivity were absent in all patients examined. A quantitative assessment of baroreceptor function was made. The resting heart period, heart period range and mean gain of alcoholics were within the control range. Quantitative histological studies were performed on the greater splanchnic nerves removed at autopsy in 4 alcoholic subjects. The myelinated fiber density fell within the control range. The absence of significant disturbance of blood pressure control correlates well with the absence of pathology in the greater splanchnic nerve.

Original languageEnglish (US)
Pages (from-to)357-364
Number of pages8
JournalBrain
Volume98
Issue number3
StatePublished - 1975
Externally publishedYes

Fingerprint

Alcoholic Neuropathy
Sympathetic Nervous System
Splanchnic Nerves
sympathetic nervous system
peripheral nervous system diseases
Neurology
Alcoholics
alcohol abuse
Nerve
Orthostatic Hypotension
Pressoreceptors
Pressure control
Sweat
Blood pressure
nerve tissue
Denervation
Pathology
heart
Range of data
sweat

ASJC Scopus subject areas

  • Neuroscience(all)
  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Mathematics(all)
  • Statistics and Probability
  • Agricultural and Biological Sciences (miscellaneous)
  • Clinical Neurology

Cite this

Low, P. A., Walsh, J. C., Huang, C. Y., & McLeod, J. G. (1975). The sympathetic nervous system in alcoholic neuropathy: a clinical and pathological study. Brain, 98(3), 357-364.

The sympathetic nervous system in alcoholic neuropathy : a clinical and pathological study. / Low, Phillip Anson; Walsh, J. C.; Huang, C. Y.; McLeod, J. G.

In: Brain, Vol. 98, No. 3, 1975, p. 357-364.

Research output: Contribution to journalArticle

Low, PA, Walsh, JC, Huang, CY & McLeod, JG 1975, 'The sympathetic nervous system in alcoholic neuropathy: a clinical and pathological study', Brain, vol. 98, no. 3, pp. 357-364.
Low, Phillip Anson ; Walsh, J. C. ; Huang, C. Y. ; McLeod, J. G. / The sympathetic nervous system in alcoholic neuropathy : a clinical and pathological study. In: Brain. 1975 ; Vol. 98, No. 3. pp. 357-364.
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