The safety of electroconvulsive therapy and lithium in combination: A case series and review of the literature

Tamara J. Dolenc, Keith G. Rasmussen

Research output: Contribution to journalArticle

47 Scopus citations


Early reports cautioned against the combination of lithium and electroconvulsive therapy (ECT), citing risk of excessive cognitive disturbance, prolonged apnea, and spontaneous seizures. However, recent case series with larger numbers of patients indicate that the combination may be used safely and with optimal efficacy in certain clinical circumstances. In this report, we describe 12 patients in whom the combination of lithium and ECT was deemed safe. We also provide a comprehensive review of published literature and provide detailed recommendations for clinical practice.

Original languageEnglish (US)
Pages (from-to)165-170
Number of pages6
JournalJournal of ECT
Issue number3
StatePublished - 2005



  • Electroconvulsive therapy
  • Lithium

ASJC Scopus subject areas

  • Psychiatry and Mental health

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