TY - JOUR
T1 - The role of novel anticoagulants in the management of venous thromboembolic disease
AU - Kitslaar, Dalene Bott
AU - Wysokinski, Waldemar E.
AU - McBane, Robert D.
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2014/8
Y1 - 2014/8
N2 - The introduction of oral direct coagulation factor inhibitors is dramatically changing the landscape of anticoagulation delivery in patients experiencing or at risk for a thrombotic event. These novel anticoagulants can be particularly attractive for health care providers, as they deliver therapeutic anticoagulation at a fixed dose, require no routine coagulation monitoring, and have few drug interactions and no food restrictions. Herein, we will review the role of these novel anticoagulants for acute venous thromboembolism treatment, primary and secondary venous thromboembolism prevention, and management during the periprocedural period.
AB - The introduction of oral direct coagulation factor inhibitors is dramatically changing the landscape of anticoagulation delivery in patients experiencing or at risk for a thrombotic event. These novel anticoagulants can be particularly attractive for health care providers, as they deliver therapeutic anticoagulation at a fixed dose, require no routine coagulation monitoring, and have few drug interactions and no food restrictions. Herein, we will review the role of these novel anticoagulants for acute venous thromboembolism treatment, primary and secondary venous thromboembolism prevention, and management during the periprocedural period.
KW - Apixaban
KW - Dabigatran
KW - Edoxaban
KW - Novel anticoagulants
KW - Rivaroxaban
KW - Venous thromboembolism treatment (VTE)
UR - http://www.scopus.com/inward/record.url?scp=84901889311&partnerID=8YFLogxK
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U2 - 10.1007/s11936-014-0326-1
DO - 10.1007/s11936-014-0326-1
M3 - Article
AN - SCOPUS:84901889311
SN - 1092-8464
VL - 16
JO - Current Treatment Options in Cardiovascular Medicine
JF - Current Treatment Options in Cardiovascular Medicine
IS - 8
M1 - 326
ER -