The impact of dual energy CT on pseudoenhancement of kidney lesions

Jan Müller, Terri J Vrtiska, Bernhard Schmidt, Ben Howe, Cynthia H McCollough, Thorsten M. Buzug, Martin Petersilka, Christian Eusemann

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Renal lesion detection and characterization using Computed Tomography is an important application in genitourinary radiology. Although in general the detection of renal lesions has been shown to be exceedingly accurate, the detection of benign renal cysts is still problematic. Under certain circumstances, the attenuation values inside a cyst increase incorrectly with an increase in the iodine concentration in the surrounding soft tissue. This so called pseudoenhancement complicates the classification of cysts and creates severe difficulties to distinguish a benign nonenhancing lesion from an enhancing mass. In the present study, the standard procedure based on a single energy 120 kV mode is compared to three dual energy modes available on the Siemens Somatom Definition Flash scanner. In order to simulate the kidney and the lesions, several plastic rods were placed inside a small container filled with different iodine concentrations. This phantom is then positioned inside water tanks of different sizes. The rods simulating the lesions are made out of a special plastic with constant HU value throughout the relevant X-ray energy range. During the project, three important aspects have been discovered: 1) for normal situations, a 100/140 Sn kV mode on the Siemens Flash scanner is similar to the traditional single energy 120 kV mode. 2) For small patient sizes, all dual energy modes show a reduction of pseudoenhancement. 3) For larger patients, only the 100/140 Sn kV mode results in a reduction of pseudoenhancement. Both the 80/140 kV and the 80/140 Sn kV mode show a worse performance than the 120 kV single energy mode in a very large phantom size.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7622
EditionPART 2
DOIs
StatePublished - 2010
EventMedical Imaging 2010: Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 15 2010Feb 18 2010

Other

OtherMedical Imaging 2010: Physics of Medical Imaging
CountryUnited States
CitySan Diego, CA
Period2/15/102/18/10

Fingerprint

kidneys
Iodine
lesions
Plastics
Kidney
Cysts
Water tanks
Radiology
cysts
Tomography
Containers
Tissue
X rays
energy
scanners
iodine
flash
rods
plastics
X-Rays

Keywords

  • Computed tomography
  • Kidney lesion
  • Pseudoenhancement

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Müller, J., Vrtiska, T. J., Schmidt, B., Howe, B., McCollough, C. H., Buzug, T. M., ... Eusemann, C. (2010). The impact of dual energy CT on pseudoenhancement of kidney lesions. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (PART 2 ed., Vol. 7622). [76223I] https://doi.org/10.1117/12.844232

The impact of dual energy CT on pseudoenhancement of kidney lesions. / Müller, Jan; Vrtiska, Terri J; Schmidt, Bernhard; Howe, Ben; McCollough, Cynthia H; Buzug, Thorsten M.; Petersilka, Martin; Eusemann, Christian.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7622 PART 2. ed. 2010. 76223I.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Müller, J, Vrtiska, TJ, Schmidt, B, Howe, B, McCollough, CH, Buzug, TM, Petersilka, M & Eusemann, C 2010, The impact of dual energy CT on pseudoenhancement of kidney lesions. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. PART 2 edn, vol. 7622, 76223I, Medical Imaging 2010: Physics of Medical Imaging, San Diego, CA, United States, 2/15/10. https://doi.org/10.1117/12.844232
Müller J, Vrtiska TJ, Schmidt B, Howe B, McCollough CH, Buzug TM et al. The impact of dual energy CT on pseudoenhancement of kidney lesions. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. PART 2 ed. Vol. 7622. 2010. 76223I https://doi.org/10.1117/12.844232
Müller, Jan ; Vrtiska, Terri J ; Schmidt, Bernhard ; Howe, Ben ; McCollough, Cynthia H ; Buzug, Thorsten M. ; Petersilka, Martin ; Eusemann, Christian. / The impact of dual energy CT on pseudoenhancement of kidney lesions. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7622 PART 2. ed. 2010.
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