TY - JOUR
T1 - The Human Genome Project
T2 - implications for the treatment of musculoskeletal disease.
AU - Jaffurs, D.
AU - Evans, C. H.
PY - 1998
Y1 - 1998
N2 - The ultimate goal of the Human Genome Project is the determination of the molecular sequence of the entire human chromosomal complement. Realization of this goal will include characterization of all the genes that cause or predispose to disease, which will most certainly lead to the development of powerful new tools for diagnosis, prevention, and treatment in all medical fields, including orthopaedics. The authors review the fundamentals of human genetics and gene mapping, summarize the progress of the Human Genome Project thus far, and discuss the implications of this research as it relates to the treatment of musculoskeletal diseases.
AB - The ultimate goal of the Human Genome Project is the determination of the molecular sequence of the entire human chromosomal complement. Realization of this goal will include characterization of all the genes that cause or predispose to disease, which will most certainly lead to the development of powerful new tools for diagnosis, prevention, and treatment in all medical fields, including orthopaedics. The authors review the fundamentals of human genetics and gene mapping, summarize the progress of the Human Genome Project thus far, and discuss the implications of this research as it relates to the treatment of musculoskeletal diseases.
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U2 - 10.5435/00124635-199801000-00001
DO - 10.5435/00124635-199801000-00001
M3 - Review article
C2 - 9692936
AN - SCOPUS:0031607695
SN - 1067-151X
VL - 6
SP - 1
EP - 14
JO - The Journal of the American Academy of Orthopaedic Surgeons
JF - The Journal of the American Academy of Orthopaedic Surgeons
IS - 1
ER -