The Human Genome Project: implications for the treatment of musculoskeletal disease.

D. Jaffurs, C. H. Evans

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

The ultimate goal of the Human Genome Project is the determination of the molecular sequence of the entire human chromosomal complement. Realization of this goal will include characterization of all the genes that cause or predispose to disease, which will most certainly lead to the development of powerful new tools for diagnosis, prevention, and treatment in all medical fields, including orthopaedics. The authors review the fundamentals of human genetics and gene mapping, summarize the progress of the Human Genome Project thus far, and discuss the implications of this research as it relates to the treatment of musculoskeletal diseases.

Original languageEnglish (US)
Pages (from-to)1-14
Number of pages14
JournalThe Journal of the American Academy of Orthopaedic Surgeons
Volume6
Issue number1
DOIs
StatePublished - Jan 1 1998

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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