The hierarchy of evidence: From unsystematic clinical observations to systematic reviews

Mohamed B. Elamin, Victor M. Montori

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Scopus citations

Abstract

A key principle of evidence-based medicine is the recognition that not all evidence is similarly protected against error, and that decisions that rely on evidence would be more confident when the evidence is more protected against bias by virtue of the methods used. Thus, a fundamental principle of evidence-based medicine is the recognition of a hierarchy of evidence. A review of the different approaches the scientific method has evolved to protect evidence from bias is presented as well as the evolution of how methodologists have built hierarchies of evidence and note the limitations and merits of these approaches.

Original languageEnglish (US)
Title of host publicationNeurology
Subtitle of host publicationAn Evidence-Based Approach
PublisherSpringer New York
Pages11-24
Number of pages14
ISBN (Electronic)9780387885551
ISBN (Print)9780387885544
DOIs
StatePublished - Jan 1 2012

Keywords

  • Evidence-based medicine
  • Hierarchy of evidence
  • Study design

ASJC Scopus subject areas

  • Medicine(all)

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