The effect of galvanic vestibular stimulation on distortion product otoacoustic emissions

Michael J. Cevette; Daniela Cocco; Gaurav N. Pradhan; Anna M. Galea; Linsey S. Wagner; Sarah R. Oakley; Benn E. Smith; David A. Zapala; Kenneth H. Brookler; Jan Stepanek

doi:10.3233/VES-2012-0444

The effect of galvanic vestibular stimulation on distortion product otoacoustic emissions

Michael J. Cevette, Daniela Cocco, Gaurav N. Pradhan, Anna M. Galea, Linsey S. Wagner, Sarah R. Oakley, Benn E. Smith, David A. Zapala, Kenneth H. Brookler, Jan Stepanek

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Galvanic stimulation has long been used as a nonmechanical means of activating the vestibular apparatus through direct action on the vestibular nerve endings. This stimulation has been reported to be safe, but no studies have examined the potential changes in the corresponding cochlear receptors. The aim of the present study was to evaluate the effect of galvanic vestibular stimulation (GVS) on distortion product otoacoustic emissions (DPOAEs). Fourteen subjects underwent DPOAEs during several conditions of GVS. The DPOAEs ranged from ∼ 1 kHz to ∼ 8 kHz at 65/55 dB for f1/f2 and with an f2/f1 ratio of 1.2. The subjects were evaluated at 10 stimulation conditions that ranged from -2.0 mA to +2.0 mA for each frequency. Statistical analysis showed no significant differences in DPOAE amplitudes for all conditions with and without GVS. Results also showed no significant differences between DPOAE amplitudes before and after GVS. Multivariate analysis found subject variability in DPOAE amplitude, which was not thought to be GVS related. Results indicated that GVS produced neither temporary nor permanent changes in DPOAEs.

Original language	English (US)
Pages (from-to)	17-25
Number of pages	9
Journal	Journal of Vestibular Research: Equilibrium and Orientation
Volume	22
Issue number	1
DOIs	https://doi.org/10.3233/VES-2012-0444
State	Published - 2012

Keywords

Distortion product otoacoustic emissions
Galvanic vestibular stimulation
Outer hair cells
Vestibular pathways

ASJC Scopus subject areas

General Neuroscience
Otorhinolaryngology
Sensory Systems
Clinical Neurology

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10.3233/VES-2012-0444

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title = "The effect of galvanic vestibular stimulation on distortion product otoacoustic emissions",

abstract = "Galvanic stimulation has long been used as a nonmechanical means of activating the vestibular apparatus through direct action on the vestibular nerve endings. This stimulation has been reported to be safe, but no studies have examined the potential changes in the corresponding cochlear receptors. The aim of the present study was to evaluate the effect of galvanic vestibular stimulation (GVS) on distortion product otoacoustic emissions (DPOAEs). Fourteen subjects underwent DPOAEs during several conditions of GVS. The DPOAEs ranged from ∼ 1 kHz to ∼ 8 kHz at 65/55 dB for f1/f2 and with an f2/f1 ratio of 1.2. The subjects were evaluated at 10 stimulation conditions that ranged from -2.0 mA to +2.0 mA for each frequency. Statistical analysis showed no significant differences in DPOAE amplitudes for all conditions with and without GVS. Results also showed no significant differences between DPOAE amplitudes before and after GVS. Multivariate analysis found subject variability in DPOAE amplitude, which was not thought to be GVS related. Results indicated that GVS produced neither temporary nor permanent changes in DPOAEs.",

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AU - Wagner, Linsey S.

AU - Oakley, Sarah R.

AU - Smith, Benn E.

AU - Zapala, David A.

AU - Brookler, Kenneth H.

AU - Stepanek, Jan

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The effect of galvanic vestibular stimulation on distortion product otoacoustic emissions

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