The blue man

A novel cutaneous manifestation of systemic amyloidosis

Mark Campbell, Allison Rosenthal, Madappa Kundranda, Amanda Pickert, David Dicaudo, Ahmet Dogan, Joseph R Mikhael

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Multiple cutaneous manifestations of amyloidosis have been described, and include periorbital purpura, plaques, nodules, and papules. Blue skin tint is not a previously described feature of cutaneous amyloidosis. We report the clinical case of a patient with known multiple myeloma and amyloidosis of the gastrointestinal tract who presented with progressive "blueness" of the skin. Dermatopathological examination and mass spectrometry of a skin biopsy specimen revealed the presence of subcutaneous amyloid light chain (AL) deposition. We believe this to be the first reported case of blue skin resulting from systemic amyloidosis.

Original languageEnglish (US)
Pages (from-to)156-159
Number of pages4
JournalAmyloid
Volume18
Issue number3
DOIs
StatePublished - Sep 2011

Fingerprint

Skin Manifestations
Amyloidosis
Skin
Purpura
Multiple Myeloma
Amyloid
Gastrointestinal Tract
Mass Spectrometry
Biopsy
Light

Keywords

  • Blue skin discoloration
  • Cutaneous amyloidosis
  • Organ-limited cutaneous amyloidosis

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Campbell, M., Rosenthal, A., Kundranda, M., Pickert, A., Dicaudo, D., Dogan, A., & Mikhael, J. R. (2011). The blue man: A novel cutaneous manifestation of systemic amyloidosis. Amyloid, 18(3), 156-159. https://doi.org/10.3109/13506129.2011.571318

The blue man : A novel cutaneous manifestation of systemic amyloidosis. / Campbell, Mark; Rosenthal, Allison; Kundranda, Madappa; Pickert, Amanda; Dicaudo, David; Dogan, Ahmet; Mikhael, Joseph R.

In: Amyloid, Vol. 18, No. 3, 09.2011, p. 156-159.

Research output: Contribution to journalArticle

Campbell, M, Rosenthal, A, Kundranda, M, Pickert, A, Dicaudo, D, Dogan, A & Mikhael, JR 2011, 'The blue man: A novel cutaneous manifestation of systemic amyloidosis', Amyloid, vol. 18, no. 3, pp. 156-159. https://doi.org/10.3109/13506129.2011.571318
Campbell M, Rosenthal A, Kundranda M, Pickert A, Dicaudo D, Dogan A et al. The blue man: A novel cutaneous manifestation of systemic amyloidosis. Amyloid. 2011 Sep;18(3):156-159. https://doi.org/10.3109/13506129.2011.571318
Campbell, Mark ; Rosenthal, Allison ; Kundranda, Madappa ; Pickert, Amanda ; Dicaudo, David ; Dogan, Ahmet ; Mikhael, Joseph R. / The blue man : A novel cutaneous manifestation of systemic amyloidosis. In: Amyloid. 2011 ; Vol. 18, No. 3. pp. 156-159.
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