Abstract
Multiple cutaneous manifestations of amyloidosis have been described, and include periorbital purpura, plaques, nodules, and papules. Blue skin tint is not a previously described feature of cutaneous amyloidosis. We report the clinical case of a patient with known multiple myeloma and amyloidosis of the gastrointestinal tract who presented with progressive "blueness" of the skin. Dermatopathological examination and mass spectrometry of a skin biopsy specimen revealed the presence of subcutaneous amyloid light chain (AL) deposition. We believe this to be the first reported case of blue skin resulting from systemic amyloidosis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 156-159 |
| Number of pages | 4 |
| Journal | Amyloid |
| Volume | 18 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 2011 |
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Keywords
- Blue skin discoloration
- Cutaneous amyloidosis
- Organ-limited cutaneous amyloidosis
ASJC Scopus subject areas
- Internal Medicine
Cite this
The blue man : A novel cutaneous manifestation of systemic amyloidosis. / Campbell, Mark; Rosenthal, Allison; Kundranda, Madappa; Pickert, Amanda; Dicaudo, David; Dogan, Ahmet; Mikhael, Joseph R.
In: Amyloid, Vol. 18, No. 3, 09.2011, p. 156-159.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The blue man
T2 - A novel cutaneous manifestation of systemic amyloidosis
AU - Campbell, Mark
AU - Rosenthal, Allison
AU - Kundranda, Madappa
AU - Pickert, Amanda
AU - Dicaudo, David
AU - Dogan, Ahmet
AU - Mikhael, Joseph R
PY - 2011/9
Y1 - 2011/9
N2 - Multiple cutaneous manifestations of amyloidosis have been described, and include periorbital purpura, plaques, nodules, and papules. Blue skin tint is not a previously described feature of cutaneous amyloidosis. We report the clinical case of a patient with known multiple myeloma and amyloidosis of the gastrointestinal tract who presented with progressive "blueness" of the skin. Dermatopathological examination and mass spectrometry of a skin biopsy specimen revealed the presence of subcutaneous amyloid light chain (AL) deposition. We believe this to be the first reported case of blue skin resulting from systemic amyloidosis.
AB - Multiple cutaneous manifestations of amyloidosis have been described, and include periorbital purpura, plaques, nodules, and papules. Blue skin tint is not a previously described feature of cutaneous amyloidosis. We report the clinical case of a patient with known multiple myeloma and amyloidosis of the gastrointestinal tract who presented with progressive "blueness" of the skin. Dermatopathological examination and mass spectrometry of a skin biopsy specimen revealed the presence of subcutaneous amyloid light chain (AL) deposition. We believe this to be the first reported case of blue skin resulting from systemic amyloidosis.
KW - Blue skin discoloration
KW - Cutaneous amyloidosis
KW - Organ-limited cutaneous amyloidosis
UR - http://www.scopus.com/inward/record.url?scp=80052250764&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052250764&partnerID=8YFLogxK
U2 - 10.3109/13506129.2011.571318
DO - 10.3109/13506129.2011.571318
M3 - Article
VL - 18
SP - 156
EP - 159
JO - Amyloid
JF - Amyloid
SN - 1350-6129
IS - 3
ER -