The activity of dopamine beta hydroxylase and methionine activating enzyme in blood of schizophrenic patients

D. L. Dunner, C. K. Cohn, R. M. Weinshilboum, R. J. Wyatt

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

The activities of dopamine beta hydroxylase (DBH) in plasma and methionine activating enzyme (MAE) in red blood cells were determined in chronic schizophrenic patients on phenothiazine medication and a control population. The mean activities of DBH and MAE were not statistically different in the schizophrenic patients; subdivision of these patients into catatonic, paranoid and undifferentiated types also failed to produce differences in the activities of these enzymes. These findings are discussed in relation to current hypotheses regarding biologic factors in the etiology of schizophrenia.

Original languageEnglish (US)
Pages (from-to)215-220
Number of pages6
JournalBiological psychiatry
Volume6
Issue number3
StatePublished - Dec 1 1973

ASJC Scopus subject areas

  • Biological Psychiatry

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