Tendon and ligament tissue engineering

Spencer P. Lake; Qian Liu; Malcolm Xing; Leanne E. Iannucci; Zhanwen Wang; Chunfeng Zhao

doi:10.1016/B978-0-12-818422-6.00056-3

Tendon and ligament tissue engineering

Spencer P. Lake, Qian Liu, Malcolm Xing, Leanne E. Iannucci, Zhanwen Wang, Chunfeng Zhao

Orthopedic Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Tendon and ligament are the major stabilizers in musculoskeletal system. Tendon/ligament injuries are common, especially in young generation. Loss of tendon/ligament support leads to tremendous functional disability. Thus restoration of tendon/ligament function after injury becomes crucial. However, the self-repair or regenerative capability of tendon/ligament is low due to their hypocellular and hypovascular nature. Therefore tissue engineering approaches to enhance tendon/ligament repair and regeneration or replace a nonrepairable tendon/ligament has indeed shed light on the future in this field. In this chapter the typical tissue-engineered tendon/ligament approaches with the basic elements and cutting edge technologies are discussed.

Original language	English (US)
Title of host publication	Principles of Tissue Engineering
Publisher	Elsevier
Pages	989-1005
Number of pages	17
ISBN (Electronic)	9780128184226
DOIs	https://doi.org/10.1016/B978-0-12-818422-6.00056-3
State	Published - Jan 1 2020

Keywords

3D bioprinting
Growth factor
Ligament
Scaffold
Stem cell
Tendon
Tissue engineering

ASJC Scopus subject areas

Economics, Econometrics and Finance(all)
Business, Management and Accounting(all)

Access to Document

10.1016/B978-0-12-818422-6.00056-3

Cite this

@inbook{265eabfb20024fbe8f6d31c6221cd469,

title = "Tendon and ligament tissue engineering",

abstract = "Tendon and ligament are the major stabilizers in musculoskeletal system. Tendon/ligament injuries are common, especially in young generation. Loss of tendon/ligament support leads to tremendous functional disability. Thus restoration of tendon/ligament function after injury becomes crucial. However, the self-repair or regenerative capability of tendon/ligament is low due to their hypocellular and hypovascular nature. Therefore tissue engineering approaches to enhance tendon/ligament repair and regeneration or replace a nonrepairable tendon/ligament has indeed shed light on the future in this field. In this chapter the typical tissue-engineered tendon/ligament approaches with the basic elements and cutting edge technologies are discussed.",

keywords = "3D bioprinting, Growth factor, Ligament, Scaffold, Stem cell, Tendon, Tissue engineering",

author = "Lake, {Spencer P.} and Qian Liu and Malcolm Xing and Iannucci, {Leanne E.} and Zhanwen Wang and Chunfeng Zhao",

year = "2020",

month = jan,

day = "1",

doi = "10.1016/B978-0-12-818422-6.00056-3",

language = "English (US)",

pages = "989--1005",

booktitle = "Principles of Tissue Engineering",

publisher = "Elsevier",

}

TY - CHAP

T1 - Tendon and ligament tissue engineering

AU - Lake, Spencer P.

AU - Liu, Qian

AU - Xing, Malcolm

AU - Iannucci, Leanne E.

AU - Wang, Zhanwen

AU - Zhao, Chunfeng

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Tendon and ligament are the major stabilizers in musculoskeletal system. Tendon/ligament injuries are common, especially in young generation. Loss of tendon/ligament support leads to tremendous functional disability. Thus restoration of tendon/ligament function after injury becomes crucial. However, the self-repair or regenerative capability of tendon/ligament is low due to their hypocellular and hypovascular nature. Therefore tissue engineering approaches to enhance tendon/ligament repair and regeneration or replace a nonrepairable tendon/ligament has indeed shed light on the future in this field. In this chapter the typical tissue-engineered tendon/ligament approaches with the basic elements and cutting edge technologies are discussed.

AB - Tendon and ligament are the major stabilizers in musculoskeletal system. Tendon/ligament injuries are common, especially in young generation. Loss of tendon/ligament support leads to tremendous functional disability. Thus restoration of tendon/ligament function after injury becomes crucial. However, the self-repair or regenerative capability of tendon/ligament is low due to their hypocellular and hypovascular nature. Therefore tissue engineering approaches to enhance tendon/ligament repair and regeneration or replace a nonrepairable tendon/ligament has indeed shed light on the future in this field. In this chapter the typical tissue-engineered tendon/ligament approaches with the basic elements and cutting edge technologies are discussed.

KW - 3D bioprinting

KW - Growth factor

KW - Ligament

KW - Scaffold

KW - Stem cell

KW - Tendon

KW - Tissue engineering

UR - http://www.scopus.com/inward/record.url?scp=85106032263&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85106032263&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-818422-6.00056-3

DO - 10.1016/B978-0-12-818422-6.00056-3

M3 - Chapter

AN - SCOPUS:85106032263

SP - 989

EP - 1005

BT - Principles of Tissue Engineering

PB - Elsevier

ER -

Tendon and ligament tissue engineering

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this