Glutaraldehyde fixation of rat peroneal nerves after killing the animal (simulated autopsy) was associated with a statistically significant decrease of density (number per unit area) of microtubules (MT) in comparison with controls (simulated biopsy). The density of MT decreased progressively with prolongation of time elapsed prior to glutaraldehyde fixation (1, 6, and 12 hr). Such a time effect was not demonstrated for density of neurofilaments.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of Neuropathology and Experimental Neurology|
|State||Published - 1976|
ASJC Scopus subject areas
- Pathology and Forensic Medicine