TY - JOUR
T1 - Stress Gastric Bleeding
T2 - Prevention Of Experimental Lesions By Intravenous Hyperalimentation
AU - DEYSINE, MAXIMO
AU - KATZKA, DAVID
AU - ROSARIO, ELISEO
PY - 1977/2
Y1 - 1977/2
N2 - Rats, weighing 125‐150 gm., were restrained under a tight wire screen for one hour at 20° C and another hour at 4° C of ambient temperature. Animals receiving no infusions, or those receiving an intravenous solution of normal saline, developed 16 ± 3 S.D. bleeding areas in their gastric mucosa. In contrast, in animals exposed to the same degree of stress who received intravenous hyperalimentation, the number of gastric stress bleeding areas counted was 4 ± 2 S.D. These results demonstrate that the delivery of calories and protein in the form of intravenous hyperalimentation can significantly reduce the incidence of gastric stress bleeding in an experimental model (P < .001).
AB - Rats, weighing 125‐150 gm., were restrained under a tight wire screen for one hour at 20° C and another hour at 4° C of ambient temperature. Animals receiving no infusions, or those receiving an intravenous solution of normal saline, developed 16 ± 3 S.D. bleeding areas in their gastric mucosa. In contrast, in animals exposed to the same degree of stress who received intravenous hyperalimentation, the number of gastric stress bleeding areas counted was 4 ± 2 S.D. These results demonstrate that the delivery of calories and protein in the form of intravenous hyperalimentation can significantly reduce the incidence of gastric stress bleeding in an experimental model (P < .001).
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U2 - 10.1111/j.1572-0241.1977.tb09922.x
DO - 10.1111/j.1572-0241.1977.tb09922.x
M3 - Article
C2 - 404873
AN - SCOPUS:0017688177
SN - 0002-9270
VL - 67
SP - 152
EP - 156
JO - The American Journal of Gastroenterology
JF - The American Journal of Gastroenterology
IS - 2
ER -