Stopping randomized trials early for benefit and estimation of treatment effects: Systematic review and meta-regression analysis

Dirk Bassler, Matthias Briel, Victor M. Montori, Melanie Lane, Paul Glasziou, Qi Zhou, Diane Heels-Ansdell, Stephen D. Walter, Gordon H. Guyatt, David N. Flynn, Mohamed B. Elamin, Mohammad Hassan Murad, Nisrin O. Abu Elnour, Julianna F. Lampropulos, Amit Sood, Rebecca J. Mullan, Patricia J. Erwin, Clare R. Bankhead, Rafael Perera, Carolina Ruiz CulebroJohn J. You, Sohail M. Mulla, Jagdeep Kaur, Kara A. Nerenberg, Holger Schünemann, Deborah J. Cook, Kristina Lutz, Christine M. Ribic, Noah Vale, German Malaga, Elie A. Akl, Ignacio Ferreira-Gonzalez, Pablo Alonso-Coello, Gerard Urrutia, Regina Kunz, Heiner C. Bucher, Alain J. Nordmann, Heike Raatz, Suzana Alves Da Silva, Fabio Tuche, Brigitte Strahm, Benjamin Djulbegovic, Neill K.J. Adhikari, Edward J. Mills, Femida Gwadry-Sridhar, Haresh Kirpalani, Heloisa P. Soares, Paul J. Karanicolas, Karen E.A. Burns, Per Olav Vandvik, Fernando Coto-Yglesias, Pedro Paulo M. Chrispim, Tim Ramsay

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