Stereoacuity in children with anisometropic amblyopia

David K. Wallace, Elizabeth L. Lazar, Michele Melia, Eileen E. Birch, Jonathan M Holmes, Kristine B. Hopkins, Raymond T. Kraker, Marjean T. Kulp, Yi Pang, Michael X. Repka, Susanna M. Tamkins, Katherine K. Weise

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Purpose: To determine factors associated with pretreatment and posttreatment stereoacuity in subjects with moderate anisometropic amblyopia. Methods: Data for subjects enrolled in seven studies conducted by the Pediatric Eye Disease Investigator Group were pooled. The sample included 633 subjects aged 3 to <18 years with anisometropic amblyopia, no heterotropia observed by cover test, and baseline amblyopic eye acuity of 20/100 or better. A subset included 248 subjects who were treated with patching or Bangerter filters and had stereoacuity testing at both the baseline and outcome examinations. Multivariate regression models identified factors associated with baseline stereoacuity and with outcome stereoacuity as measured by the Randot Preschool Stereoacuity test. Results: Better baseline stereoacuity was associated with better baseline amblyopic eye acuity (P < 0.001), less anisometropia (P = 0.03), and anisometropia due to astigmatism alone (P < 0.001). Better outcome stereoacuity was associated with better baseline stereoacuity (P < 0.001) and better amblyopic eye acuity at outcome (P < 0.001). Among 48 subjects whose amblyopic eye visual acuity at outcome was 20/25 or better and within one line of the fellow eye, stereoacuity was worse than that of children with normal vision of the same age. Conclusions: In children with anisometropic amblyopia of 20/40 to 20/100 inclusive, better posttreatment stereoacuity is associated with better baseline stereoacuity and better posttreatment amblyopic eye acuity. Even if their visual acuity deficit resolves, many children with anisometropic amblyopia have stereoacuity worse than that of nonamblyopic children of the same age.

Original languageEnglish (US)
Pages (from-to)455-461
Number of pages7
JournalJournal of AAPOS
Volume15
Issue number5
DOIs
StatePublished - Oct 2011

Fingerprint

Amblyopia
Anisometropia
Visual Acuity
Astigmatism
Eye Diseases
Research Personnel
Pediatrics

ASJC Scopus subject areas

  • Ophthalmology
  • Pediatrics, Perinatology, and Child Health

Cite this

Wallace, D. K., Lazar, E. L., Melia, M., Birch, E. E., Holmes, J. M., Hopkins, K. B., ... Weise, K. K. (2011). Stereoacuity in children with anisometropic amblyopia. Journal of AAPOS, 15(5), 455-461. https://doi.org/10.1016/j.jaapos.2011.06.007

Stereoacuity in children with anisometropic amblyopia. / Wallace, David K.; Lazar, Elizabeth L.; Melia, Michele; Birch, Eileen E.; Holmes, Jonathan M; Hopkins, Kristine B.; Kraker, Raymond T.; Kulp, Marjean T.; Pang, Yi; Repka, Michael X.; Tamkins, Susanna M.; Weise, Katherine K.

In: Journal of AAPOS, Vol. 15, No. 5, 10.2011, p. 455-461.

Research output: Contribution to journalArticle

Wallace, DK, Lazar, EL, Melia, M, Birch, EE, Holmes, JM, Hopkins, KB, Kraker, RT, Kulp, MT, Pang, Y, Repka, MX, Tamkins, SM & Weise, KK 2011, 'Stereoacuity in children with anisometropic amblyopia', Journal of AAPOS, vol. 15, no. 5, pp. 455-461. https://doi.org/10.1016/j.jaapos.2011.06.007
Wallace DK, Lazar EL, Melia M, Birch EE, Holmes JM, Hopkins KB et al. Stereoacuity in children with anisometropic amblyopia. Journal of AAPOS. 2011 Oct;15(5):455-461. https://doi.org/10.1016/j.jaapos.2011.06.007
Wallace, David K. ; Lazar, Elizabeth L. ; Melia, Michele ; Birch, Eileen E. ; Holmes, Jonathan M ; Hopkins, Kristine B. ; Kraker, Raymond T. ; Kulp, Marjean T. ; Pang, Yi ; Repka, Michael X. ; Tamkins, Susanna M. ; Weise, Katherine K. / Stereoacuity in children with anisometropic amblyopia. In: Journal of AAPOS. 2011 ; Vol. 15, No. 5. pp. 455-461.
@article{5530ba0047c446788e882ebbb1dddff3,
title = "Stereoacuity in children with anisometropic amblyopia",
abstract = "Purpose: To determine factors associated with pretreatment and posttreatment stereoacuity in subjects with moderate anisometropic amblyopia. Methods: Data for subjects enrolled in seven studies conducted by the Pediatric Eye Disease Investigator Group were pooled. The sample included 633 subjects aged 3 to <18 years with anisometropic amblyopia, no heterotropia observed by cover test, and baseline amblyopic eye acuity of 20/100 or better. A subset included 248 subjects who were treated with patching or Bangerter filters and had stereoacuity testing at both the baseline and outcome examinations. Multivariate regression models identified factors associated with baseline stereoacuity and with outcome stereoacuity as measured by the Randot Preschool Stereoacuity test. Results: Better baseline stereoacuity was associated with better baseline amblyopic eye acuity (P < 0.001), less anisometropia (P = 0.03), and anisometropia due to astigmatism alone (P < 0.001). Better outcome stereoacuity was associated with better baseline stereoacuity (P < 0.001) and better amblyopic eye acuity at outcome (P < 0.001). Among 48 subjects whose amblyopic eye visual acuity at outcome was 20/25 or better and within one line of the fellow eye, stereoacuity was worse than that of children with normal vision of the same age. Conclusions: In children with anisometropic amblyopia of 20/40 to 20/100 inclusive, better posttreatment stereoacuity is associated with better baseline stereoacuity and better posttreatment amblyopic eye acuity. Even if their visual acuity deficit resolves, many children with anisometropic amblyopia have stereoacuity worse than that of nonamblyopic children of the same age.",
author = "Wallace, {David K.} and Lazar, {Elizabeth L.} and Michele Melia and Birch, {Eileen E.} and Holmes, {Jonathan M} and Hopkins, {Kristine B.} and Kraker, {Raymond T.} and Kulp, {Marjean T.} and Yi Pang and Repka, {Michael X.} and Tamkins, {Susanna M.} and Weise, {Katherine K.}",
year = "2011",
month = "10",
doi = "10.1016/j.jaapos.2011.06.007",
language = "English (US)",
volume = "15",
pages = "455--461",
journal = "Journal of AAPOS",
issn = "1091-8531",
publisher = "Mosby Inc.",
number = "5",

}

TY - JOUR

T1 - Stereoacuity in children with anisometropic amblyopia

AU - Wallace, David K.

AU - Lazar, Elizabeth L.

AU - Melia, Michele

AU - Birch, Eileen E.

AU - Holmes, Jonathan M

AU - Hopkins, Kristine B.

AU - Kraker, Raymond T.

AU - Kulp, Marjean T.

AU - Pang, Yi

AU - Repka, Michael X.

AU - Tamkins, Susanna M.

AU - Weise, Katherine K.

PY - 2011/10

Y1 - 2011/10

N2 - Purpose: To determine factors associated with pretreatment and posttreatment stereoacuity in subjects with moderate anisometropic amblyopia. Methods: Data for subjects enrolled in seven studies conducted by the Pediatric Eye Disease Investigator Group were pooled. The sample included 633 subjects aged 3 to <18 years with anisometropic amblyopia, no heterotropia observed by cover test, and baseline amblyopic eye acuity of 20/100 or better. A subset included 248 subjects who were treated with patching or Bangerter filters and had stereoacuity testing at both the baseline and outcome examinations. Multivariate regression models identified factors associated with baseline stereoacuity and with outcome stereoacuity as measured by the Randot Preschool Stereoacuity test. Results: Better baseline stereoacuity was associated with better baseline amblyopic eye acuity (P < 0.001), less anisometropia (P = 0.03), and anisometropia due to astigmatism alone (P < 0.001). Better outcome stereoacuity was associated with better baseline stereoacuity (P < 0.001) and better amblyopic eye acuity at outcome (P < 0.001). Among 48 subjects whose amblyopic eye visual acuity at outcome was 20/25 or better and within one line of the fellow eye, stereoacuity was worse than that of children with normal vision of the same age. Conclusions: In children with anisometropic amblyopia of 20/40 to 20/100 inclusive, better posttreatment stereoacuity is associated with better baseline stereoacuity and better posttreatment amblyopic eye acuity. Even if their visual acuity deficit resolves, many children with anisometropic amblyopia have stereoacuity worse than that of nonamblyopic children of the same age.

AB - Purpose: To determine factors associated with pretreatment and posttreatment stereoacuity in subjects with moderate anisometropic amblyopia. Methods: Data for subjects enrolled in seven studies conducted by the Pediatric Eye Disease Investigator Group were pooled. The sample included 633 subjects aged 3 to <18 years with anisometropic amblyopia, no heterotropia observed by cover test, and baseline amblyopic eye acuity of 20/100 or better. A subset included 248 subjects who were treated with patching or Bangerter filters and had stereoacuity testing at both the baseline and outcome examinations. Multivariate regression models identified factors associated with baseline stereoacuity and with outcome stereoacuity as measured by the Randot Preschool Stereoacuity test. Results: Better baseline stereoacuity was associated with better baseline amblyopic eye acuity (P < 0.001), less anisometropia (P = 0.03), and anisometropia due to astigmatism alone (P < 0.001). Better outcome stereoacuity was associated with better baseline stereoacuity (P < 0.001) and better amblyopic eye acuity at outcome (P < 0.001). Among 48 subjects whose amblyopic eye visual acuity at outcome was 20/25 or better and within one line of the fellow eye, stereoacuity was worse than that of children with normal vision of the same age. Conclusions: In children with anisometropic amblyopia of 20/40 to 20/100 inclusive, better posttreatment stereoacuity is associated with better baseline stereoacuity and better posttreatment amblyopic eye acuity. Even if their visual acuity deficit resolves, many children with anisometropic amblyopia have stereoacuity worse than that of nonamblyopic children of the same age.

UR - http://www.scopus.com/inward/record.url?scp=81855227001&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=81855227001&partnerID=8YFLogxK

U2 - 10.1016/j.jaapos.2011.06.007

DO - 10.1016/j.jaapos.2011.06.007

M3 - Article

VL - 15

SP - 455

EP - 461

JO - Journal of AAPOS

JF - Journal of AAPOS

SN - 1091-8531

IS - 5

ER -