Staging and imaging of sarcoma

Carola A.S. Arndt, Andrea Ferrari

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Staging of soft tissue sarcoma, Ewing sarcoma, and osteosarcoma involves MRI of the primary tumor, computed tomography of the chest, and, in the case of Ewing Sarcoma and rhabdomyosarcoma, evaluation of the bone marrow. FDG PET imaging, when available, is replacing technetium bone scanning for evaluation of metastatic disease in sarcomas and is being investigated to determine response to treatment and prognosis. Staging and risk assignment for rhabdomyosarcoma (RMS) have undergone significant evolution since the original description of the clinical group assignment and modified TNM system. The next generation of RMS studies in the Children’s Oncology Group will use fusion status instead of histologic determination for treatment assignment. For selected low-risk patients, some staging studies can be omitted. There remain some differences in risk and treatment assignment between the European Pediatric Soft Tissue Sarcoma Group and the Children’s Oncology Group.

Original languageEnglish (US)
Title of host publicationPediatric Oncology
PublisherSpringer Science and Business Media Deutschland GmbH
Pages37-46
Number of pages10
DOIs
StatePublished - 2021

Publication series

NamePediatric Oncology
ISSN (Print)1613-5318
ISSN (Electronic)2191-0812

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology

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