Solitary Fibrous Tumor of the Cerebellopontine Angle with Salivary Gland Heterotopia: A Unique Presentation

Fausto Rodriguez, Bernd W. Scheithauer, Daniel M. Ockner, Caterina Giannini

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

We report the unique association of a solitary fibrous tumor of the cerebellopontine angle with ectopic salivary gland tissue in a 53-year-old woman. The patient, diagnosed 21 years earlier with a right cerebellopontine angle fibrous meningioma, presented with a recurrent mass, which, upon surgical removal, showed features of a solitary fibrous tumor. Strong and diffuse immunoreactivity to CD34 and BCL-2 and a negative epithelial membrane antigen immunostain confirmed the diagnosis. Admixed with the spindle cell neoplasm, a bland glandular element composed of small glands and variably dilated tubules was noted. The vague tubuloacinar arrangement of the glands and the presence of acinar cells with a granular, periodic acid-Schiff-positive, basophilic cytoplasm, resembling serous type acini, were features of benign, although ectopic, salivary gland tissue. The presence of a myoepithelial cell layer, surrounding some of the acini and highlighted by the smooth muscle actin immunostain, strengthened this interpretation.

Original languageEnglish (US)
Pages (from-to)139-142
Number of pages4
JournalAmerican Journal of Surgical Pathology
Volume28
Issue number1
DOIs
StatePublished - Jan 1 2004

Keywords

  • Cerebellopontine angle
  • Ectopia
  • Heterotopia
  • Salivary gland
  • Solitary fibrous tumor

ASJC Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine

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