Selection of cross-resistance following exposure of Pseudomonas aeruginosa clinical isolates to ciprofloxacin or cefepime

Samer A. Alyaseen, Kerryl E. Piper, Mark S. Rouse, James M. Steckelberg, Robin Patel

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Exposure of ciprofloxacin- and cefepime-susceptible Pseudomonas aeruginosa isolates to increasing concentrations of ciprofloxacin selected for ciprofloxacin resistance in 26/27 and cefepime nonsusceptibility in 7/27 isolates. Exposure of the isolates to increasing concentrations of cefepime selected for cefepime nonsusceptibility in 20/27 isolates but not for ciprofloxacin resistance.

Original languageEnglish (US)
Pages (from-to)2543-2545
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume49
Issue number6
DOIs
StatePublished - Jun 2005

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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