Secondary Sclerosing Cholangitis. Pathogenesis, Diagnosis, and Management.

Mohamad H. Imam, Jayant A. Talwalkar, Keith D. Lindor

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Secondary sclerosing cholangitis (SSC) is an aggressive and rare disease with intricate pathogenesis and multiple causes. Understanding the specific cause underlying each case of SSC is crucial in the clinical management of the disease. Radiologic imaging can help diagnose SSC and hence institute management in a timely manner. Management may encompass simple interventions, such as supportive therapy, antibiotics, and monitoring, or more serious measures, such as surgery, endoscopic intervention, or liver transplantation. Patients with AIDS cholangiopathy have limited therapeutic options and worsened survival. The disease should always be highly suspected in patients with primary sclerosing cholangitis with questionable diagnosis.

Original languageEnglish (US)
Pages (from-to)269-277
Number of pages9
JournalClinics in Liver Disease
Volume17
Issue number2
DOIs
StatePublished - May 2013

Fingerprint

Sclerosing Cholangitis
Disease Management
Rare Diseases
Liver Transplantation
Acquired Immunodeficiency Syndrome
Anti-Bacterial Agents
Survival
Therapeutics

Keywords

  • Cholangiopathy
  • Clinical management
  • Complications
  • Liver transplantation
  • Outcomes

ASJC Scopus subject areas

  • Hepatology

Cite this

Secondary Sclerosing Cholangitis. Pathogenesis, Diagnosis, and Management. / Imam, Mohamad H.; Talwalkar, Jayant A.; Lindor, Keith D.

In: Clinics in Liver Disease, Vol. 17, No. 2, 05.2013, p. 269-277.

Research output: Contribution to journalArticle

Imam, Mohamad H. ; Talwalkar, Jayant A. ; Lindor, Keith D. / Secondary Sclerosing Cholangitis. Pathogenesis, Diagnosis, and Management. In: Clinics in Liver Disease. 2013 ; Vol. 17, No. 2. pp. 269-277.
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