Screening for lung cancer: For patients at ncreased risk for lung cancer, it works

James R. Jett, David Eric Midthun

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Screening for lung cancer is not currently recommended, even in persons at high risk for this condition. Most patients with lung cancer present with symptomatic disease that is usually at an incurable, advanced stage. The recently reported NLST (National Lung Screening Trial) showed a 20% decrease in deaths from lung cancer in high-risk persons undergoing screening with low-dose computed tomography of the chest compared with chest radiography. The high-risk group included in the trial comprised asymptomatic persons aged 55 to 74 years, with smoking history of at least 30 pack-years. Screening with low-dose computed tomography detected more cases of early-stage lung cancer and fewer cases of advanced-stage cancer, confirming that screening has shifted the stage of cancer at diagnosis and provides more persons with the opportunity for curative treatment. Although computed tomography screening has risks and limitations, the 20% decrease in deaths is the single most dramatic decrease ever reported for deaths from lung cancer, with the possible exception of smoking cessation. Physicians should offer computed tomography screening for lung cancer to patients who fit the high-risk profile defined in the NLST.

Original languageEnglish (US)
Pages (from-to)540-542
Number of pages3
JournalAnnals of Internal Medicine
Volume155
Issue number8
StatePublished - Oct 18 2011

Fingerprint

Lung Neoplasms
Tomography
Thorax
Lung
Smoking Cessation
Early Detection of Cancer
Radiography
Smoking
Physicians
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Screening for lung cancer : For patients at ncreased risk for lung cancer, it works. / Jett, James R.; Midthun, David Eric.

In: Annals of Internal Medicine, Vol. 155, No. 8, 18.10.2011, p. 540-542.

Research output: Contribution to journalArticle

@article{4b6814a3ed964b3d860d5259c2e1770e,
title = "Screening for lung cancer: For patients at ncreased risk for lung cancer, it works",
abstract = "Screening for lung cancer is not currently recommended, even in persons at high risk for this condition. Most patients with lung cancer present with symptomatic disease that is usually at an incurable, advanced stage. The recently reported NLST (National Lung Screening Trial) showed a 20{\%} decrease in deaths from lung cancer in high-risk persons undergoing screening with low-dose computed tomography of the chest compared with chest radiography. The high-risk group included in the trial comprised asymptomatic persons aged 55 to 74 years, with smoking history of at least 30 pack-years. Screening with low-dose computed tomography detected more cases of early-stage lung cancer and fewer cases of advanced-stage cancer, confirming that screening has shifted the stage of cancer at diagnosis and provides more persons with the opportunity for curative treatment. Although computed tomography screening has risks and limitations, the 20{\%} decrease in deaths is the single most dramatic decrease ever reported for deaths from lung cancer, with the possible exception of smoking cessation. Physicians should offer computed tomography screening for lung cancer to patients who fit the high-risk profile defined in the NLST.",
author = "Jett, {James R.} and Midthun, {David Eric}",
year = "2011",
month = "10",
day = "18",
language = "English (US)",
volume = "155",
pages = "540--542",
journal = "Annals of Internal Medicine",
issn = "0003-4819",
publisher = "American College of Physicians",
number = "8",

}

TY - JOUR

T1 - Screening for lung cancer

T2 - For patients at ncreased risk for lung cancer, it works

AU - Jett, James R.

AU - Midthun, David Eric

PY - 2011/10/18

Y1 - 2011/10/18

N2 - Screening for lung cancer is not currently recommended, even in persons at high risk for this condition. Most patients with lung cancer present with symptomatic disease that is usually at an incurable, advanced stage. The recently reported NLST (National Lung Screening Trial) showed a 20% decrease in deaths from lung cancer in high-risk persons undergoing screening with low-dose computed tomography of the chest compared with chest radiography. The high-risk group included in the trial comprised asymptomatic persons aged 55 to 74 years, with smoking history of at least 30 pack-years. Screening with low-dose computed tomography detected more cases of early-stage lung cancer and fewer cases of advanced-stage cancer, confirming that screening has shifted the stage of cancer at diagnosis and provides more persons with the opportunity for curative treatment. Although computed tomography screening has risks and limitations, the 20% decrease in deaths is the single most dramatic decrease ever reported for deaths from lung cancer, with the possible exception of smoking cessation. Physicians should offer computed tomography screening for lung cancer to patients who fit the high-risk profile defined in the NLST.

AB - Screening for lung cancer is not currently recommended, even in persons at high risk for this condition. Most patients with lung cancer present with symptomatic disease that is usually at an incurable, advanced stage. The recently reported NLST (National Lung Screening Trial) showed a 20% decrease in deaths from lung cancer in high-risk persons undergoing screening with low-dose computed tomography of the chest compared with chest radiography. The high-risk group included in the trial comprised asymptomatic persons aged 55 to 74 years, with smoking history of at least 30 pack-years. Screening with low-dose computed tomography detected more cases of early-stage lung cancer and fewer cases of advanced-stage cancer, confirming that screening has shifted the stage of cancer at diagnosis and provides more persons with the opportunity for curative treatment. Although computed tomography screening has risks and limitations, the 20% decrease in deaths is the single most dramatic decrease ever reported for deaths from lung cancer, with the possible exception of smoking cessation. Physicians should offer computed tomography screening for lung cancer to patients who fit the high-risk profile defined in the NLST.

UR - http://www.scopus.com/inward/record.url?scp=80054727277&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80054727277&partnerID=8YFLogxK

M3 - Article

C2 - 21893615

AN - SCOPUS:80054727277

VL - 155

SP - 540

EP - 542

JO - Annals of Internal Medicine

JF - Annals of Internal Medicine

SN - 0003-4819

IS - 8

ER -