Abstract
Objective: The aim of this study was to quantify the impact of age on the potential benefits of screening for colorectal cancer. Method: Life-table analysis of the risks of dying from colorectal cancer or from all other causes was performed. The impact of prematurely stopping screening was compared to the maximal potential benefit expected from lifelong screening. Results: The relative proportion of deaths from colorectal cancer compared to all other causes was greatest at the age of 62 and diminished thereafter. A total of 80% of the maximal benefit from screening was achieved by screening till the age of 82. The impact of prematurely stopping screening varied with gender and race. Discussion: The maximal societal benefit will be achieved by screening at younger ages because of competing causes of mortality among older people. Gender and ethnicity should be considered in individual decisions to stop screening at a given age.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 126-139 |
| Number of pages | 14 |
| Journal | Journal of Aging and Health |
| Volume | 20 |
| Issue number | 1 |
| DOIs | |
| State | Published - Feb 2008 |
| Externally published | Yes |
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Keywords
- Actuarial analysis
- Age
- Life expectancy
- Life-table analysis
ASJC Scopus subject areas
- Geriatrics and Gerontology
- Aging
- Health(social science)
- Health Professions(all)
Cite this
Screening for colorectal cancer in elderly persons : Who should we screen and when can we stop? / Maheshwari, Shail; Patel, Tushar C; Patel, Parita.
In: Journal of Aging and Health, Vol. 20, No. 1, 02.2008, p. 126-139.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Screening for colorectal cancer in elderly persons
T2 - Who should we screen and when can we stop?
AU - Maheshwari, Shail
AU - Patel, Tushar C
AU - Patel, Parita
PY - 2008/2
Y1 - 2008/2
N2 - Objective: The aim of this study was to quantify the impact of age on the potential benefits of screening for colorectal cancer. Method: Life-table analysis of the risks of dying from colorectal cancer or from all other causes was performed. The impact of prematurely stopping screening was compared to the maximal potential benefit expected from lifelong screening. Results: The relative proportion of deaths from colorectal cancer compared to all other causes was greatest at the age of 62 and diminished thereafter. A total of 80% of the maximal benefit from screening was achieved by screening till the age of 82. The impact of prematurely stopping screening varied with gender and race. Discussion: The maximal societal benefit will be achieved by screening at younger ages because of competing causes of mortality among older people. Gender and ethnicity should be considered in individual decisions to stop screening at a given age.
AB - Objective: The aim of this study was to quantify the impact of age on the potential benefits of screening for colorectal cancer. Method: Life-table analysis of the risks of dying from colorectal cancer or from all other causes was performed. The impact of prematurely stopping screening was compared to the maximal potential benefit expected from lifelong screening. Results: The relative proportion of deaths from colorectal cancer compared to all other causes was greatest at the age of 62 and diminished thereafter. A total of 80% of the maximal benefit from screening was achieved by screening till the age of 82. The impact of prematurely stopping screening varied with gender and race. Discussion: The maximal societal benefit will be achieved by screening at younger ages because of competing causes of mortality among older people. Gender and ethnicity should be considered in individual decisions to stop screening at a given age.
KW - Actuarial analysis
KW - Age
KW - Life expectancy
KW - Life-table analysis
UR - http://www.scopus.com/inward/record.url?scp=37849048057&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=37849048057&partnerID=8YFLogxK
U2 - 10.1177/0898264307309939
DO - 10.1177/0898264307309939
M3 - Article
C2 - 18089764
AN - SCOPUS:37849048057
VL - 20
SP - 126
EP - 139
JO - Journal of Aging and Health
JF - Journal of Aging and Health
SN - 0898-2643
IS - 1
ER -