Scleritis Due to Histoplasmosis

Lauren A. Dalvin; Steven B. Thom; Joaquín J. García; Hind J. Fadel; Keith H. Baratz

doi:10.1097/ICO.0000000000000733

Scleritis Due to Histoplasmosis

Lauren A. Dalvin, Steven B. Thom, Joaquín J. García, Hind J. Fadel, Keith H. Baratz

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: To describe the first-documented case of histoplasma scleritis in an immunocompetent patient. Methods: Medical and pathological records of the patient described were reviewed. Results: A 77-year-old immunocompetent man presented with necrotizing scleritis. Biopsy was consistent with histoplasma species, and culture results confirmed a causative agent of Histoplasma capsulatum. The patient required a long course of treatment, which included topical voriconazole and amphotericin, oral itraconazole and voriconazole, intravenous amphotericin, and periocular voriconazole and amphotericin. After 8 months of treatment, the patient's scleritis resolved, and he maintained good visual acuity. Conclusions: To our knowledge, this is the second report of histoplasma scleritis in the literature and the first report in an immunocompetent patient.

Original language	English (US)
Pages (from-to)	402-404
Number of pages	3
Journal	Cornea
Volume	35
Issue number	3
DOIs	https://doi.org/10.1097/ICO.0000000000000733
State	Published - Jan 1 2016

Keywords

Fungal
Histoplasmosis
Infection
Scleritis

ASJC Scopus subject areas

Ophthalmology

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10.1097/ICO.0000000000000733

Cite this

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title = "Scleritis Due to Histoplasmosis",

abstract = "Purpose: To describe the first-documented case of histoplasma scleritis in an immunocompetent patient. Methods: Medical and pathological records of the patient described were reviewed. Results: A 77-year-old immunocompetent man presented with necrotizing scleritis. Biopsy was consistent with histoplasma species, and culture results confirmed a causative agent of Histoplasma capsulatum. The patient required a long course of treatment, which included topical voriconazole and amphotericin, oral itraconazole and voriconazole, intravenous amphotericin, and periocular voriconazole and amphotericin. After 8 months of treatment, the patient's scleritis resolved, and he maintained good visual acuity. Conclusions: To our knowledge, this is the second report of histoplasma scleritis in the literature and the first report in an immunocompetent patient.",

keywords = "Fungal, Histoplasmosis, Infection, Scleritis",

author = "Dalvin, {Lauren A.} and Thom, {Steven B.} and Garc{\'i}a, {Joaqu{\'i}n J.} and Fadel, {Hind J.} and Baratz, {Keith H.}",

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language = "English (US)",

volume = "35",

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journal = "Cornea",

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TY - JOUR

T1 - Scleritis Due to Histoplasmosis

AU - Dalvin, Lauren A.

AU - Thom, Steven B.

AU - García, Joaquín J.

AU - Fadel, Hind J.

AU - Baratz, Keith H.

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Purpose: To describe the first-documented case of histoplasma scleritis in an immunocompetent patient. Methods: Medical and pathological records of the patient described were reviewed. Results: A 77-year-old immunocompetent man presented with necrotizing scleritis. Biopsy was consistent with histoplasma species, and culture results confirmed a causative agent of Histoplasma capsulatum. The patient required a long course of treatment, which included topical voriconazole and amphotericin, oral itraconazole and voriconazole, intravenous amphotericin, and periocular voriconazole and amphotericin. After 8 months of treatment, the patient's scleritis resolved, and he maintained good visual acuity. Conclusions: To our knowledge, this is the second report of histoplasma scleritis in the literature and the first report in an immunocompetent patient.

AB - Purpose: To describe the first-documented case of histoplasma scleritis in an immunocompetent patient. Methods: Medical and pathological records of the patient described were reviewed. Results: A 77-year-old immunocompetent man presented with necrotizing scleritis. Biopsy was consistent with histoplasma species, and culture results confirmed a causative agent of Histoplasma capsulatum. The patient required a long course of treatment, which included topical voriconazole and amphotericin, oral itraconazole and voriconazole, intravenous amphotericin, and periocular voriconazole and amphotericin. After 8 months of treatment, the patient's scleritis resolved, and he maintained good visual acuity. Conclusions: To our knowledge, this is the second report of histoplasma scleritis in the literature and the first report in an immunocompetent patient.

KW - Fungal

KW - Histoplasmosis

KW - Infection

KW - Scleritis

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Scleritis Due to Histoplasmosis

Abstract

Keywords

ASJC Scopus subject areas

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