Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer

Aman Anand, Martin Bues, William G. Rule, Sameer R. Keole, Chris J. Beltran, Jun Yin, Michael Haddock, Christopher Hallemeier, Robert C. Miller, Jonathan B. Ashman

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.

Original languageEnglish (US)
JournalRadiotherapy and Oncology
DOIs
StateAccepted/In press - Jan 29 2015

Fingerprint

Proton Therapy
Anus Neoplasms
Radiotherapy
Anal Canal
Photons
Squamous Cell Carcinoma
Bone Marrow
Therapeutics

Keywords

  • Anal cancer
  • Bone marrow sparing
  • Spot scanning proton planning
  • Whole pelvis proton therapy

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Hematology

Cite this

Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer. / Anand, Aman; Bues, Martin; Rule, William G.; Keole, Sameer R.; Beltran, Chris J.; Yin, Jun; Haddock, Michael; Hallemeier, Christopher; Miller, Robert C.; Ashman, Jonathan B.

In: Radiotherapy and Oncology, 29.01.2015.

Research output: Contribution to journalArticle

Anand, Aman ; Bues, Martin ; Rule, William G. ; Keole, Sameer R. ; Beltran, Chris J. ; Yin, Jun ; Haddock, Michael ; Hallemeier, Christopher ; Miller, Robert C. ; Ashman, Jonathan B. / Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer. In: Radiotherapy and Oncology. 2015.
@article{821a5a804cea4f9297d4c7dcd4afad98,
title = "Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer",
abstract = "An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50{\%}, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.",
keywords = "Anal cancer, Bone marrow sparing, Spot scanning proton planning, Whole pelvis proton therapy",
author = "Aman Anand and Martin Bues and Rule, {William G.} and Keole, {Sameer R.} and Beltran, {Chris J.} and Jun Yin and Michael Haddock and Christopher Hallemeier and Miller, {Robert C.} and Ashman, {Jonathan B.}",
year = "2015",
month = "1",
day = "29",
doi = "10.1016/j.radonc.2015.10.027",
language = "English (US)",
journal = "Radiotherapy and Oncology",
issn = "0167-8140",
publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer

AU - Anand, Aman

AU - Bues, Martin

AU - Rule, William G.

AU - Keole, Sameer R.

AU - Beltran, Chris J.

AU - Yin, Jun

AU - Haddock, Michael

AU - Hallemeier, Christopher

AU - Miller, Robert C.

AU - Ashman, Jonathan B.

PY - 2015/1/29

Y1 - 2015/1/29

N2 - An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.

AB - An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.

KW - Anal cancer

KW - Bone marrow sparing

KW - Spot scanning proton planning

KW - Whole pelvis proton therapy

UR - http://www.scopus.com/inward/record.url?scp=84948798839&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84948798839&partnerID=8YFLogxK

U2 - 10.1016/j.radonc.2015.10.027

DO - 10.1016/j.radonc.2015.10.027

M3 - Article

C2 - 26597231

AN - SCOPUS:84948798839

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

SN - 0167-8140

ER -