Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer

Aman Anand; Martin Bues; William G. Rule; Sameer R. Keole; Chris J. Beltran; Jun Yin; Michael G. Haddock; Christopher L. Hallemeier; Robert C. Miller; Jonathan B. Ashman

doi:10.1016/j.radonc.2015.10.027

Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer

Aman Anand, Martin Bues, William G. Rule, Sameer R. Keole, Chris J. Beltran, Jun Yin, Michael G. Haddock, Christopher L. Hallemeier, Robert C. Miller, Jonathan B. Ashman

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.

Original language	English (US)
Pages (from-to)	505-508
Number of pages	4
Journal	Radiotherapy and Oncology
Volume	117
Issue number	3
DOIs	https://doi.org/10.1016/j.radonc.2015.10.027
State	Published - Dec 1 2015

Keywords

Anal cancer
Bone marrow sparing
Spot scanning proton planning
Whole pelvis proton therapy

ASJC Scopus subject areas

Hematology
Oncology
Radiology Nuclear Medicine and imaging

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10.1016/j.radonc.2015.10.027

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title = "Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer",

abstract = "An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.",

keywords = "Anal cancer, Bone marrow sparing, Spot scanning proton planning, Whole pelvis proton therapy",

author = "Aman Anand and Martin Bues and Rule, {William G.} and Keole, {Sameer R.} and Beltran, {Chris J.} and Jun Yin and Haddock, {Michael G.} and Hallemeier, {Christopher L.} and Miller, {Robert C.} and Ashman, {Jonathan B.}",

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year = "2015",

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doi = "10.1016/j.radonc.2015.10.027",

language = "English (US)",

volume = "117",

pages = "505--508",

journal = "Radiotherapy and Oncology",

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T1 - Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer

AU - Anand, Aman

AU - Bues, Martin

AU - Rule, William G.

AU - Keole, Sameer R.

AU - Beltran, Chris J.

AU - Yin, Jun

AU - Haddock, Michael G.

AU - Hallemeier, Christopher L.

AU - Miller, Robert C.

AU - Ashman, Jonathan B.

PY - 2015/12/1

Y1 - 2015/12/1

N2 - An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.

AB - An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.

KW - Anal cancer

KW - Bone marrow sparing

KW - Spot scanning proton planning

KW - Whole pelvis proton therapy

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AN - SCOPUS:84948798839

SN - 0167-8140

VL - 117

SP - 505

EP - 508

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

IS - 3

ER -

Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer

Abstract

Keywords

ASJC Scopus subject areas

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