Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer

Aman Anand, Martin Bues, William G. Rule, Sameer R. Keole, Chris J. Beltran, Jun Yin, Michael Haddock, Christopher Hallemeier, Robert C. Miller, Jonathan B. Ashman

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.

Original languageEnglish (US)
JournalRadiotherapy and Oncology
DOIs
StateAccepted/In press - Jan 29 2015

Keywords

  • Anal cancer
  • Bone marrow sparing
  • Spot scanning proton planning
  • Whole pelvis proton therapy

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Hematology

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