Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer

Aman Anand; Martin Bues; William G. Rule; Sameer R. Keole; Chris J. Beltran; Jun Yin; Michael Haddock; Christopher Hallemeier; Robert C. Miller; Jonathan B. Ashman

doi:10.1016/j.radonc.2015.10.027

Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer

Aman Anand, Martin Bues, William G. Rule, Sameer R. Keole, Chris J. Beltran, Jun Yin, Michael Haddock, Christopher Hallemeier, Robert C. Miller, Jonathan B. Ashman

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.

Original language	English (US)
Journal	Radiotherapy and Oncology
DOIs	https://doi.org/10.1016/j.radonc.2015.10.027
State	Accepted/In press - Jan 29 2015

Keywords

Anal cancer
Bone marrow sparing
Spot scanning proton planning
Whole pelvis proton therapy

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging
Hematology

Access to Document

10.1016/j.radonc.2015.10.027

Cite this

@article{821a5a804cea4f9297d4c7dcd4afad98,

title = "Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer",

abstract = "An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.",

keywords = "Anal cancer, Bone marrow sparing, Spot scanning proton planning, Whole pelvis proton therapy",

author = "Aman Anand and Martin Bues and Rule, {William G.} and Keole, {Sameer R.} and Beltran, {Chris J.} and Jun Yin and Michael Haddock and Christopher Hallemeier and Miller, {Robert C.} and Ashman, {Jonathan B.}",

year = "2015",

month = jan,

day = "29",

doi = "10.1016/j.radonc.2015.10.027",

language = "English (US)",

journal = "Radiotherapy and Oncology",

issn = "0167-8140",

publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer

AU - Anand, Aman

AU - Bues, Martin

AU - Rule, William G.

AU - Keole, Sameer R.

AU - Beltran, Chris J.

AU - Yin, Jun

AU - Haddock, Michael

AU - Hallemeier, Christopher

AU - Miller, Robert C.

AU - Ashman, Jonathan B.

PY - 2015/1/29

Y1 - 2015/1/29

N2 - An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.

AB - An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.

KW - Anal cancer

KW - Bone marrow sparing

KW - Spot scanning proton planning

KW - Whole pelvis proton therapy

UR - http://www.scopus.com/inward/record.url?scp=84948798839&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84948798839&partnerID=8YFLogxK

U2 - 10.1016/j.radonc.2015.10.027

DO - 10.1016/j.radonc.2015.10.027

M3 - Article

C2 - 26597231

AN - SCOPUS:84948798839

SN - 0167-8140

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

ER -

Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this