Satisfaction after contralateral prophylactic mastectomy: The significance of mastectomy type, reconstructive complications, and body appearance

Marlene H. Frost, Jeffrey M. Slezak, Nho V. Tran, Constance I. Williams, Joanne L. Johnson, John E. Woods, Paul M. Petty, John H. Donohue, Clive S. Grant, Jeff A Sloan, Thomas A. Sellers, Lynn C. Hartmann

Research output: Contribution to journalArticle

141 Citations (Scopus)

Abstract

Purpose: Contralateral prophylactic mastectomy (CPM) is one option for reducing the risk of a second breast cancer in women with a personal and family history of breast cancer. Few data are available regarding satisfaction, psychological, and social function after CPM. The purpose of this research is to evaluate women's long-term satisfaction with CPM, factors influencing satisfaction, and psychological and social function after CPM. Patients and Methods: This was a descriptive study of all women with a family history of breast cancer, known to be alive, who elected CPM at Mayo Clinic (Rochester, MN) between 1960 and 1993 (n = 621). Ninety-four percent of the women (n = 583) completed a study-specific questionnaire. Results: A mean of 10.3 years after the procedure, the majority of women (83%) were satisfied with their CPM. A smaller number were neutral (8%) or dissatisfied (9%). Women who had a subcutaneous mastectomy had more problems with reconstruction, and fewer of these women were satisfied than women with simple mastectomy. Decreased satisfaction with CPM was associated with decreased satisfaction with appearance, complications with reconstruction, reconstruction after CPM, and increased level of stress in life. The majority of women experienced no change or favorable effects in self-esteem (83%), level of stress in life (83%), and emotional stability (88%). Satisfaction with body appearance, feelings of femininity, and sexual relationships were the most adversely affected with 33%, 26%, and 23% of the women responding negatively. Conclusion: Although most women are satisfied with CPM, each woman should weigh the benefits alongside the potential adverse effects.

Original languageEnglish (US)
Pages (from-to)7849-7856
Number of pages8
JournalJournal of Clinical Oncology
Volume23
Issue number31
DOIs
StatePublished - 2005

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Mastectomy
Breast Neoplasms
Psychological Stress
Prophylactic Mastectomy
Subcutaneous Mastectomy
Simple Mastectomy
Psychology
Femininity
Second Primary Neoplasms
Self Concept
Emotions

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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Satisfaction after contralateral prophylactic mastectomy : The significance of mastectomy type, reconstructive complications, and body appearance. / Frost, Marlene H.; Slezak, Jeffrey M.; Tran, Nho V.; Williams, Constance I.; Johnson, Joanne L.; Woods, John E.; Petty, Paul M.; Donohue, John H.; Grant, Clive S.; Sloan, Jeff A; Sellers, Thomas A.; Hartmann, Lynn C.

In: Journal of Clinical Oncology, Vol. 23, No. 31, 2005, p. 7849-7856.

Research output: Contribution to journalArticle

Frost, MH, Slezak, JM, Tran, NV, Williams, CI, Johnson, JL, Woods, JE, Petty, PM, Donohue, JH, Grant, CS, Sloan, JA, Sellers, TA & Hartmann, LC 2005, 'Satisfaction after contralateral prophylactic mastectomy: The significance of mastectomy type, reconstructive complications, and body appearance', Journal of Clinical Oncology, vol. 23, no. 31, pp. 7849-7856. https://doi.org/10.1200/JCO.2005.09.233
Frost, Marlene H. ; Slezak, Jeffrey M. ; Tran, Nho V. ; Williams, Constance I. ; Johnson, Joanne L. ; Woods, John E. ; Petty, Paul M. ; Donohue, John H. ; Grant, Clive S. ; Sloan, Jeff A ; Sellers, Thomas A. ; Hartmann, Lynn C. / Satisfaction after contralateral prophylactic mastectomy : The significance of mastectomy type, reconstructive complications, and body appearance. In: Journal of Clinical Oncology. 2005 ; Vol. 23, No. 31. pp. 7849-7856.
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abstract = "Purpose: Contralateral prophylactic mastectomy (CPM) is one option for reducing the risk of a second breast cancer in women with a personal and family history of breast cancer. Few data are available regarding satisfaction, psychological, and social function after CPM. The purpose of this research is to evaluate women's long-term satisfaction with CPM, factors influencing satisfaction, and psychological and social function after CPM. Patients and Methods: This was a descriptive study of all women with a family history of breast cancer, known to be alive, who elected CPM at Mayo Clinic (Rochester, MN) between 1960 and 1993 (n = 621). Ninety-four percent of the women (n = 583) completed a study-specific questionnaire. Results: A mean of 10.3 years after the procedure, the majority of women (83{\%}) were satisfied with their CPM. A smaller number were neutral (8{\%}) or dissatisfied (9{\%}). Women who had a subcutaneous mastectomy had more problems with reconstruction, and fewer of these women were satisfied than women with simple mastectomy. Decreased satisfaction with CPM was associated with decreased satisfaction with appearance, complications with reconstruction, reconstruction after CPM, and increased level of stress in life. The majority of women experienced no change or favorable effects in self-esteem (83{\%}), level of stress in life (83{\%}), and emotional stability (88{\%}). Satisfaction with body appearance, feelings of femininity, and sexual relationships were the most adversely affected with 33{\%}, 26{\%}, and 23{\%} of the women responding negatively. Conclusion: Although most women are satisfied with CPM, each woman should weigh the benefits alongside the potential adverse effects.",
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T1 - Satisfaction after contralateral prophylactic mastectomy

T2 - The significance of mastectomy type, reconstructive complications, and body appearance

AU - Frost, Marlene H.

AU - Slezak, Jeffrey M.

AU - Tran, Nho V.

AU - Williams, Constance I.

AU - Johnson, Joanne L.

AU - Woods, John E.

AU - Petty, Paul M.

AU - Donohue, John H.

AU - Grant, Clive S.

AU - Sloan, Jeff A

AU - Sellers, Thomas A.

AU - Hartmann, Lynn C.

PY - 2005

Y1 - 2005

N2 - Purpose: Contralateral prophylactic mastectomy (CPM) is one option for reducing the risk of a second breast cancer in women with a personal and family history of breast cancer. Few data are available regarding satisfaction, psychological, and social function after CPM. The purpose of this research is to evaluate women's long-term satisfaction with CPM, factors influencing satisfaction, and psychological and social function after CPM. Patients and Methods: This was a descriptive study of all women with a family history of breast cancer, known to be alive, who elected CPM at Mayo Clinic (Rochester, MN) between 1960 and 1993 (n = 621). Ninety-four percent of the women (n = 583) completed a study-specific questionnaire. Results: A mean of 10.3 years after the procedure, the majority of women (83%) were satisfied with their CPM. A smaller number were neutral (8%) or dissatisfied (9%). Women who had a subcutaneous mastectomy had more problems with reconstruction, and fewer of these women were satisfied than women with simple mastectomy. Decreased satisfaction with CPM was associated with decreased satisfaction with appearance, complications with reconstruction, reconstruction after CPM, and increased level of stress in life. The majority of women experienced no change or favorable effects in self-esteem (83%), level of stress in life (83%), and emotional stability (88%). Satisfaction with body appearance, feelings of femininity, and sexual relationships were the most adversely affected with 33%, 26%, and 23% of the women responding negatively. Conclusion: Although most women are satisfied with CPM, each woman should weigh the benefits alongside the potential adverse effects.

AB - Purpose: Contralateral prophylactic mastectomy (CPM) is one option for reducing the risk of a second breast cancer in women with a personal and family history of breast cancer. Few data are available regarding satisfaction, psychological, and social function after CPM. The purpose of this research is to evaluate women's long-term satisfaction with CPM, factors influencing satisfaction, and psychological and social function after CPM. Patients and Methods: This was a descriptive study of all women with a family history of breast cancer, known to be alive, who elected CPM at Mayo Clinic (Rochester, MN) between 1960 and 1993 (n = 621). Ninety-four percent of the women (n = 583) completed a study-specific questionnaire. Results: A mean of 10.3 years after the procedure, the majority of women (83%) were satisfied with their CPM. A smaller number were neutral (8%) or dissatisfied (9%). Women who had a subcutaneous mastectomy had more problems with reconstruction, and fewer of these women were satisfied than women with simple mastectomy. Decreased satisfaction with CPM was associated with decreased satisfaction with appearance, complications with reconstruction, reconstruction after CPM, and increased level of stress in life. The majority of women experienced no change or favorable effects in self-esteem (83%), level of stress in life (83%), and emotional stability (88%). Satisfaction with body appearance, feelings of femininity, and sexual relationships were the most adversely affected with 33%, 26%, and 23% of the women responding negatively. Conclusion: Although most women are satisfied with CPM, each woman should weigh the benefits alongside the potential adverse effects.

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