TY - JOUR
T1 - Safety of symptom-limited cardiopulmonary exercise testing in patients with aortic stenosis
AU - Dhoble, Abhijeet
AU - Sarano, Maurice E.
AU - Kopecky, Stephen L.
AU - Thomas, Randal J.
AU - Hayes, Courtney L.
AU - Allison, Thomas G.
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2012/7
Y1 - 2012/7
N2 - BACKGROUND: There are no published data on the safety of cardiopulmonary exercise testing in patients with aortic stenosis. METHODS: In this retrospective descriptive study, we examined 347 consecutive patients with aortic stenosis who underwent cardiopulmonary exercise testing at a tertiary referral center. We recorded major events including death, nonfatal major events (cardiac arrest, symptomatic or sustained ventricular or supraventricular tachycardia, myocardial infarction, and syncope), and minor events such as hypotension, nonsustained supraventricular and ventricular arrhythmias, positive electrocardiographic changes, and angina. RESULTS: Of 347 patients, 65 (19%) had mild, 145 (42%) had moderate, and 137 (40%) had severe aortic stenosis by echocardiographic criteria. No major events occurred during the tests. Minor events occurred in a total of 97 patients (28%), including 10 patients who developed supraventricular arrhythmias without hypotension; and one who had asymptomatic nonsustained ventricular tachycardia. CONCLUSION: Symptom-limited cardiopulmonary exercise testing in cardiology-referred patients with aortic stenosis with preserved systolic function appears to be associated with very low risk of major adverse cardiovascular events during testing.
AB - BACKGROUND: There are no published data on the safety of cardiopulmonary exercise testing in patients with aortic stenosis. METHODS: In this retrospective descriptive study, we examined 347 consecutive patients with aortic stenosis who underwent cardiopulmonary exercise testing at a tertiary referral center. We recorded major events including death, nonfatal major events (cardiac arrest, symptomatic or sustained ventricular or supraventricular tachycardia, myocardial infarction, and syncope), and minor events such as hypotension, nonsustained supraventricular and ventricular arrhythmias, positive electrocardiographic changes, and angina. RESULTS: Of 347 patients, 65 (19%) had mild, 145 (42%) had moderate, and 137 (40%) had severe aortic stenosis by echocardiographic criteria. No major events occurred during the tests. Minor events occurred in a total of 97 patients (28%), including 10 patients who developed supraventricular arrhythmias without hypotension; and one who had asymptomatic nonsustained ventricular tachycardia. CONCLUSION: Symptom-limited cardiopulmonary exercise testing in cardiology-referred patients with aortic stenosis with preserved systolic function appears to be associated with very low risk of major adverse cardiovascular events during testing.
KW - Aortic stenosis
KW - Cardiopulmonary testing
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U2 - 10.1016/j.amjmed.2012.01.012
DO - 10.1016/j.amjmed.2012.01.012
M3 - Article
C2 - 22560172
AN - SCOPUS:84862639150
SN - 0002-9343
VL - 125
SP - 704
EP - 708
JO - American Journal of Medicine
JF - American Journal of Medicine
IS - 7
ER -