Rumination syndrome: When to suspect and how to treat

Research output: Contribution to journalReview article

Abstract

Purpose of reviewRumination syndrome is a gastrointestinal disorder characterized by effortless regurgitation of recently ingested food. The disorder is rare, but likely under-recognized and leads to impaired quality of life among those affected. This review discusses recent studies which examined the pathophysiology, diagnoses and therapy of rumination syndrome.Recent findingsThe pathogenesis of rumination syndrome remains incompletely understood. Therapeutic options, which appear effective, include behavioral therapy with diaphragmatic breathing and pharmacotherapy with baclofen. A randomized trial of behavioral therapy, biofeedback therapy led to a 74%+/- 6% reduction in rumination activity (from 29+/- 6 before to 7+/- 2 daily events after intervention) vs. 1%+/- 14% during sham (from 21+/- 2 before to 21+/- 4 daily events after intervention) (P=.001). A recent randomized trial of baclofen at a dose of 10mg three times daily led to symptomatic improvement in 63% of patients with rumination syndrome.SummaryThis review summarizes a clinical approach to diagnosing and treating rumination syndrome. Behavioral therapy consisting of diaphragmatic breathing, with or without biofeedback, remains the most effective treatment strategy for patients with rumination syndrome.

Original languageEnglish (US)
Pages (from-to)387-393
Number of pages7
JournalCurrent Opinion in Gastroenterology
Volume35
Issue number4
DOIs
StatePublished - Jul 1 2019

Keywords

  • biofeedback therapy
  • functional gastrointestinal disorder
  • rumination syndrome

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'Rumination syndrome: When to suspect and how to treat'. Together they form a unique fingerprint.

  • Cite this