TY - JOUR
T1 - Routine vs extended outpatient EEG for the detection of interictal epileptiform discharges
AU - Burkholder, David B.
AU - Britton, Jeffrey W.
AU - Rajasekaran, Vijayalakshmi
AU - Fabris, Rachel R.
AU - Cherian, Perumpillichira J.
AU - Kelly-Williams, Kristen M.
AU - So, Elson L.
AU - Nickels, Katherine C.
AU - Wong-Kisiel, Lily C.
AU - Lagerlund, Terrence D.
AU - Cascino, Gregory D.
AU - Worrell, Gregory A.
AU - Wirrell, Elaine C.
N1 - Publisher Copyright:
© 2016 American Academy of Neurology.
PY - 2016/4/19
Y1 - 2016/4/19
N2 - Objective: To compare the yield of epileptiform abnormalities on 30-minute recordings with those greater than 45 minutes. Methods: We performed a prospective observational cross-sectional study of all outpatient routine EEGs comparing the rate of interictal epileptiform discharges (IEDs) and clinical events during the initial 30 minutes (routine) with those occurring in the remaining 30-60 minutes (extended). A relative increase of 10% was considered clinically significant. Results: EEGs from 1,803 patients were included; overall EEG duration was 59.4 minutes (SD ±6.5). Of 426 patients with IEDs at any time during the EEG, 81 (19.1%, 95% confidence interval 15.6-23) occurred only after the initial 30 minutes. The rate of late IEDs was not associated with age, indication, IED type, or sleep deprivation. Longer recording times also increased event capture rate by approximately 30%. Conclusions: The yield of IED and event detection is increased in extended outpatient EEGs compared to 30-minute studies.
AB - Objective: To compare the yield of epileptiform abnormalities on 30-minute recordings with those greater than 45 minutes. Methods: We performed a prospective observational cross-sectional study of all outpatient routine EEGs comparing the rate of interictal epileptiform discharges (IEDs) and clinical events during the initial 30 minutes (routine) with those occurring in the remaining 30-60 minutes (extended). A relative increase of 10% was considered clinically significant. Results: EEGs from 1,803 patients were included; overall EEG duration was 59.4 minutes (SD ±6.5). Of 426 patients with IEDs at any time during the EEG, 81 (19.1%, 95% confidence interval 15.6-23) occurred only after the initial 30 minutes. The rate of late IEDs was not associated with age, indication, IED type, or sleep deprivation. Longer recording times also increased event capture rate by approximately 30%. Conclusions: The yield of IED and event detection is increased in extended outpatient EEGs compared to 30-minute studies.
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U2 - 10.1212/WNL.0000000000002592
DO - 10.1212/WNL.0000000000002592
M3 - Article
C2 - 26984946
AN - SCOPUS:84964350783
SN - 0028-3878
VL - 86
SP - 1524
EP - 1530
JO - Neurology
JF - Neurology
IS - 16
ER -